20 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CALM1	CALM1 isoform 3; Belongs to the calmodulin family. (150 aa)
	CASQ2	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (399 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	CALM3	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family. (149 aa)
	FKBP1B	Peptidylprolyl isomerase. (108 aa)
	CK820_G0037244	NTSR1 isoform 1; Belongs to the G-protein coupled receptor 1 family. (350 aa)
	PKD2	Polycystin 2, transient receptor potential cation channel. (968 aa)
	CLIC2	Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (247 aa)
	TRDN	TRDN isoform 1. (730 aa)
	GSTO1	Glutathione S-transferase omega 1. (241 aa)
	ENSPTRP00000063671	annotation not available (122 aa)
	RYR2	RYR2 isoform 1. (4941 aa)
	CLIC2-2	Chloride intracellular channel 2. (247 aa)
	SRI	SRI isoform 1. (205 aa)
	SRI-2	SRI isoform 5. (237 aa)
	ENSPTRP00000082718	annotation not available (235 aa)
	ENSPTRP00000085680	annotation not available (88 aa)
	MTLN	LINC00116 isoform 1. (139 aa)
	ENSPTRP00000090392	annotation not available (93 aa)
	CK820_G0029100	SRI isoform 2. (98 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CALM1	CALM3	ENSPTRP00000082789	ENSPTRP00000019197	CALM1 isoform 3; Belongs to the calmodulin family.	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	0.772
CALM1	CASQ2	ENSPTRP00000082789	ENSPTRP00000001966	CALM1 isoform 3; Belongs to the calmodulin family.	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	0.507
CALM1	FKBP1B	ENSPTRP00000082789	ENSPTRP00000020110	CALM1 isoform 3; Belongs to the calmodulin family.	Peptidylprolyl isomerase.	0.569
CALM1	RYR2	ENSPTRP00000082789	ENSPTRP00000064508	CALM1 isoform 3; Belongs to the calmodulin family.	RYR2 isoform 1.	0.562
CALM1	TRDN	ENSPTRP00000082789	ENSPTRP00000058505	CALM1 isoform 3; Belongs to the calmodulin family.	TRDN isoform 1.	0.464
CALM3	CALM1	ENSPTRP00000019197	ENSPTRP00000082789	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	CALM1 isoform 3; Belongs to the calmodulin family.	0.772
CALM3	CASQ2	ENSPTRP00000019197	ENSPTRP00000001966	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	0.511
CALM3	ENSPTRP00000090392	ENSPTRP00000019197	ENSPTRP00000090392	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	annotation not available	0.773
CALM3	FKBP1B	ENSPTRP00000019197	ENSPTRP00000020110	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	Peptidylprolyl isomerase.	0.898
CALM3	RYR2	ENSPTRP00000019197	ENSPTRP00000064508	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	RYR2 isoform 1.	0.994
CALM3	SRI	ENSPTRP00000019197	ENSPTRP00000080641	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	SRI isoform 1.	0.522
CALM3	SRI-2	ENSPTRP00000019197	ENSPTRP00000081612	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	SRI isoform 5.	0.522
CALM3	TRDN	ENSPTRP00000019197	ENSPTRP00000058505	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	TRDN isoform 1.	0.703
CASQ2	CALM1	ENSPTRP00000001966	ENSPTRP00000082789	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	CALM1 isoform 3; Belongs to the calmodulin family.	0.507
CASQ2	CALM3	ENSPTRP00000001966	ENSPTRP00000019197	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	0.511
CASQ2	ENSPTRP00000090392	ENSPTRP00000001966	ENSPTRP00000090392	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	annotation not available	0.507
CASQ2	FKBP1B	ENSPTRP00000001966	ENSPTRP00000020110	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Peptidylprolyl isomerase.	0.683
CASQ2	RYR2	ENSPTRP00000001966	ENSPTRP00000064508	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	RYR2 isoform 1.	0.991
CASQ2	SRI	ENSPTRP00000001966	ENSPTRP00000080641	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	SRI isoform 1.	0.595
CASQ2	SRI-2	ENSPTRP00000001966	ENSPTRP00000081612	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	SRI isoform 5.	0.595