STRINGSTRING
RIPOR2 RIPOR2 SKI SKI MTOR MTOR TMOD4 TMOD4 LMNA LMNA CASQ1 CASQ1 CSRP1 CSRP1 LMOD1 LMOD1 ACTA1 ACTA1 SMYD3 SMYD3 NEBL NEBL MYOZ1 MYOZ1 BMPR1A BMPR1A ANKRD1 ANKRD1 MYOF MYOF NRAP NRAP ADM ADM MYOD1 MYOD1 CSRP3 CSRP3 EFEMP2 EFEMP2 WNT10B WNT10B STAC3 STAC3 ATP2A2 ATP2A2 CFL2 CFL2 ASB2 ASB2 TMOD3 TMOD3 MYLK3 MYLK3 CHRNB1 CHRNB1 MAP2K4 MAP2K4 TCAP TCAP RAMP2 RAMP2 AFG3L2 AFG3L2 ALPK2 ALPK2 TMEM182 TMEM182 BIN1 BIN1 TTN TTN MYL9 MYL9 CXADR CXADR CAV3 CAV3 LMOD3 LMOD3 WDR1 WDR1 SGCB SGCB MYOZ2 MYOZ2 EDNRA EDNRA SORBS2 SORBS2 ISL1 ISL1 PTCD2 PTCD2 LOX LOX MEGF10 MEGF10 NKX2-5 NKX2-5 SRF SRF TBX18 TBX18 BVES BVES ATG5 ATG5 HEY2 HEY2 SMO SMO MYOM2 MYOM2 SGCZ SGCZ NKX2-6 NKX2-6 PLEC PLEC MYORG MYORG PGM5 PGM5 ENG ENG NOTCH1 NOTCH1 TMOD1 TMOD1 LRRC10 LRRC10 TPM1 TPM1 KRT19 KRT19 AKAP13 AKAP13 CK820_G0014110 CK820_G0014110 SIX4 SIX4 MYOG MYOG KLHL40 KLHL40 PRKAR1A PRKAR1A ANK2 ANK2 MYPN MYPN NFATC2 NFATC2 FLNC FLNC LMOD2 LMOD2 DNER DNER CDK1 CDK1 PROX1 PROX1 CNTNAP1 CNTNAP1 DYSF DYSF LOC453361 LOC453361 CACNB4 CACNB4 MAML1 MAML1 COMP COMP OBSL1 OBSL1 BIN3 BIN3 SYNPO2L SYNPO2L SGCD SGCD CAV2 CAV2 KDM1A KDM1A ALPK3 ALPK3 TNNT1 TNNT1 CXADR-2 CXADR-2 MYH11 MYH11 HES1 HES1 SLC8A1 SLC8A1 ENSPTRP00000064416 ENSPTRP00000064416 PPP3CB PPP3CB C10H10orf113 C10H10orf113 ENSPTRP00000065655 ENSPTRP00000065655 SDC1 SDC1 KEL KEL ENSPTRP00000066578 ENSPTRP00000066578 CSRP2 CSRP2 SMO-2 SMO-2 PPP3CA PPP3CA ENSPTRP00000067778 ENSPTRP00000067778 IGF1 IGF1 OBSCN OBSCN MYO18B MYO18B LRRC10B LRRC10B TBX5 TBX5 DMD DMD ITGB1 ITGB1 SIX1 SIX1 MEF2A MEF2A ENSPTRP00000070878 ENSPTRP00000070878 ACTL10-2 ACTL10-2 TNNT2 TNNT2 ENSPTRP00000071419 ENSPTRP00000071419 WFIKKN1 WFIKKN1 MYH3 MYH3 ENSPTRP00000072925 ENSPTRP00000072925 NEB NEB FER1L5 FER1L5 R3HDM1 R3HDM1 TNNT3 TNNT3 CACNA1S CACNA1S GATA4 GATA4 PDLIM5 PDLIM5 BMP10 BMP10 CFLAR CFLAR MYL2 MYL2 ACTN2 ACTN2 FHOD3 FHOD3 PDGFRB PDGFRB ACTG1 ACTG1 ACTN4 ACTN4 ZMPSTE24 ZMPSTE24 MYH7 MYH7 FLII FLII P2RX2 P2RX2 LDB3 LDB3 HOMER1 HOMER1 ADRA1A ADRA1A DMD-2 DMD-2 TBX3 TBX3 HNRNPU HNRNPU WFIKKN2 WFIKKN2 SPG11 SPG11 ACTN3 ACTN3 FHL2 FHL2 SELENON SELENON RCAN1 RCAN1 MYH6 MYH6 NFATC4 NFATC4 ACTN1 ACTN1 ACTL10 ACTL10 BCL2 BCL2 CK820_G0030361 CK820_G0030361 TMOD2 TMOD2 KLHL41 KLHL41 SHOX2 SHOX2 ADPRHL1 ADPRHL1 RYR1 RYR1 ENSPTRP00000093210 ENSPTRP00000093210 UCHL1 UCHL1 R3HDM2 R3HDM2 ENSPTRP00000093588 ENSPTRP00000093588 SYPL2 SYPL2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RIPOR2RHO family interacting cell polarization regulator 2. (1068 aa)
SKIV-ski sarcoma viral oncogene homolog (Avian). (736 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
TMOD4TMOD4 isoform 2. (345 aa)
LMNALMNA isoform 8; Belongs to the intermediate filament family. (664 aa)
CASQ1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (396 aa)
CSRP1Cysteine and glycine-rich protein 1. (193 aa)
LMOD1LMOD1 isoform 2. (600 aa)
ACTA1Actin alpha 1, skeletal muscle. (377 aa)
SMYD3SET and MYND domain containing 3. (428 aa)
NEBLNEBL isoform 5. (1014 aa)
MYOZ1MYOZ1 isoform 1. (299 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
ANKRD1Ankyrin repeat domain 1 (Cardiac muscle). (319 aa)
MYOFMYOF isoform 3. (2061 aa)
NRAPNRAP isoform 1. (1730 aa)
ADMAdrenomedullin. (185 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (320 aa)
CSRP3Cysteine and glycine rich protein 3. (194 aa)
EFEMP2EGF containing fibulin-like extracellular matrix protein 2. (443 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
STAC3SH3 and cysteine rich domain 3. (364 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
CFL2Cofilin 2 (Muscle); Belongs to the actin-binding proteins ADF family. (166 aa)
ASB2Ankyrin repeat and SOCS box containing 2. (635 aa)
TMOD3Tropomodulin 3 (Ubiquitous). (352 aa)
MYLK3MYLK3 isoform 1. (819 aa)
CHRNB1Cholinergic receptor, nicotinic, beta 1 (Muscle). (501 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (410 aa)
TCAPTCAP isoform 1. (167 aa)
RAMP2Receptor (G protein-coupled) activity modifying protein 2. (175 aa)
AFG3L2AFG3 like matrix AAA peptidase subunit 2. (797 aa)
ALPK2ALPK2 isoform 1. (2171 aa)
TMEM182Transmembrane protein 182. (229 aa)
BIN1Bridging integrator 1. (597 aa)
TTNTTN isoform 3. (32000 aa)
MYL9Myosin, light chain 9, regulatory. (172 aa)
CXADRCXADR Ig-like cell adhesion molecule. (365 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
LMOD3LMOD3 isoform 1. (560 aa)
WDR1WD repeat domain 1. (606 aa)
SGCBSarcoglycan beta. (320 aa)
MYOZ2MYOZ2 isoform 1. (264 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
SORBS2Sorbin and SH3 domain containing 2. (1202 aa)
ISL1ISL LIM homeobox 1. (349 aa)
PTCD2Pentatricopeptide repeat domain 2. (388 aa)
LOXLOX isoform 1. (417 aa)
MEGF10MEGF10 isoform 2. (1140 aa)
NKX2-5NKX2-5 isoform 1. (325 aa)
SRFSerum response factor (C-fos serum response element-binding transcription factor). (508 aa)
TBX18T-box transcription factor 18. (607 aa)
BVESBlood vessel epicardial substance. (360 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif 2. (337 aa)
SMOSMO isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
MYOM2MYOM2 isoform 2. (1428 aa)
SGCZSarcoglycan zeta. (312 aa)
NKX2-6NKX2-6 isoform 1. (301 aa)
PLECPLEC isoform 2. (4684 aa)
MYORGMyogenesis regulating glycosidase (putative); Belongs to the glycosyl hydrolase 31 family. (714 aa)
PGM5Uncharacterized protein; Belongs to the phosphohexose mutase family. (567 aa)
ENGENG isoform 1. (658 aa)
NOTCH1NOTCH1 isoform 1. (2555 aa)
TMOD1TMOD1 isoform 1. (359 aa)
LRRC10Leucine rich repeat containing 10. (277 aa)
TPM1TPM1 isoform 3; Belongs to the tropomyosin family. (326 aa)
KRT19KRT19 isoform 1; Belongs to the intermediate filament family. (400 aa)
AKAP13A-kinase anchoring protein 13. (2813 aa)
CK820_G0014110KEL isoform 1. (732 aa)
SIX4SIX homeobox 4. (781 aa)
MYOGMYOG isoform 1. (249 aa)
KLHL40Kelch like family member 40. (621 aa)
PRKAR1AProtein kinase, cAMP-dependent, regulatory, type I, alpha (Tissue specific extinguisher 1). (381 aa)
ANK2ANK2 isoform 1. (3957 aa)
MYPNMYPN isoform 1. (1320 aa)
NFATC2NFATC2 isoform 4. (938 aa)
FLNCFilamin C, gamma. (2725 aa)
LMOD2LMOD2 isoform 1. (548 aa)
DNERDelta/notch-like EGF repeat containing. (739 aa)
CDK1Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
PROX1Prospero homeobox 1. (737 aa)
CNTNAP1Contactin associated protein 1. (1384 aa)
DYSFDYSF isoform 8. (2119 aa)
LOC453361CAPN3 isoform 4; Belongs to the peptidase C2 family. (821 aa)
CACNB4Calcium voltage-gated channel auxiliary subunit beta 4. (520 aa)
MAML1MAML1 isoform 1. (1016 aa)
COMPCartilage oligomeric matrix protein. (757 aa)
OBSL1OBSL1 isoform 6. (1895 aa)
BIN3Bridging integrator 3. (253 aa)
SYNPO2LSYNPO2L isoform 2. (978 aa)
SGCDSarcoglycan, delta (35kDa dystrophin-associated glycoprotein). (290 aa)
CAV2Caveolin-2; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (B [...] (162 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa)
ALPK3ALPK3 isoform 1. (1901 aa)
TNNT1Troponin T1, slow skeletal type. (278 aa)
CXADR-2CXADR Ig-like cell adhesion molecule. (188 aa)
MYH11MYH11 isoform 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2009 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
ENSPTRP00000064416annotation not available (502 aa)
PPP3CBSerine/threonine-protein phosphatase. (526 aa)
C10H10orf113C10orf113 isoform 2. (79 aa)
ENSPTRP00000065655annotation not available (349 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (310 aa)
KELKell metallo-endopeptidase. (732 aa)
ENSPTRP00000066578annotation not available (310 aa)
CSRP2Cysteine and glycine rich protein 2. (243 aa)
SMO-2Smoothened, frizzled class receptor. (786 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
ENSPTRP00000067778annotation not available (85 aa)
IGF1Insulin-like growth factor 1 (Somatomedin C). (196 aa)
OBSCNObscurin, cytoskeletal calmodulin and titin-interacting RhoGEF. (8919 aa)
MYO18BMYO18B isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2550 aa)
LRRC10BLeucine rich repeat containing 10B. (292 aa)
TBX5T-box transcription factor 5. (518 aa)
DMDDMD isoform 3. (3685 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
SIX1SIX homeobox 1. (284 aa)
MEF2AMyocyte enhancer factor 2A. (507 aa)
ENSPTRP00000070878annotation not available (324 aa)
ACTL10-2Chromosome 20 open reading frame 134; Belongs to the actin family. (245 aa)
TNNT2Troponin T type 2 (Cardiac). (298 aa)
ENSPTRP00000071419annotation not available (371 aa)
WFIKKN1WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1. (548 aa)
MYH3Myosin, heavy chain 3, skeletal muscle, embryonic; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1940 aa)
ENSPTRP00000072925annotation not available (372 aa)
NEBNEB isoform 5. (8417 aa)
FER1L5FER1L5 isoform 5. (1974 aa)
R3HDM1R3H domain containing 1. (1102 aa)
TNNT3Troponin T3, fast skeletal type. (269 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
GATA4GATA binding protein 4. (443 aa)
PDLIM5PDLIM5 isoform 14. (625 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
CFLARCASP8 and FADD-like apoptosis regulator; Belongs to the peptidase C14A family. (480 aa)
MYL2Myosin, light chain 2, regulatory, cardiac, slow. (166 aa)
ACTN2ACTN2 isoform 2. (894 aa)
FHOD3Formin homology 2 domain containing 3. (1622 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
ACTG1ACTG1 isoform 13. (375 aa)
ACTN4Actinin, alpha 4. (931 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (480 aa)
MYH7Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1935 aa)
FLIIFLII actin remodeling protein. (1273 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (497 aa)
LDB3LIM domain binding 3. (732 aa)
HOMER1HOMER1 isoform 1. (344 aa)
ADRA1AAdrenoceptor alpha 1A. (495 aa)
DMD-2Dystrophin. (643 aa)
TBX3T-box transcription factor 3. (743 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U (Scaffold attachment factor A). (825 aa)
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (576 aa)
SPG11SPG11 isoform 4. (2443 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (944 aa)
FHL2FHL2 isoform 4. (389 aa)
SELENONT0161445 isoform 2. (581 aa)
RCAN1RCAN1 isoform 6. (276 aa)
MYH6MYH6 isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2050 aa)
NFATC4Nuclear factor of activated T cells 4. (933 aa)
ACTN1Actinin, alpha 1. (870 aa)
ACTL10Actin like 10. (245 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
CK820_G0030361RYR1 isoform 5. (4901 aa)
TMOD2Tropomodulin 2 (Neuronal). (351 aa)
KLHL41Kelch repeat and BTB domain-containing protein 5/10. (606 aa)
SHOX2SHOX2 isoform 2. (343 aa)
ADPRHL1ADPRHL1 isoform 2. (1673 aa)
RYR1RYR1 isoform 3. (5037 aa)
ENSPTRP00000093210annotation not available (261 aa)
UCHL1Ubiquitin carboxyl-terminal hydrolase. (260 aa)
R3HDM2R3HDM2 isoform 5. (1035 aa)
ENSPTRP00000093588annotation not available (361 aa)
SYPL2Synaptophysin like 2. (272 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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