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TBX18 TBX18 NKX2-5 NKX2-5 ISL1 ISL1 SORBS2 SORBS2 ENSPTRP00000072925 ENSPTRP00000072925 NEB NEB GATA4 GATA4 PDLIM5 PDLIM5 BMP10 BMP10 MYL2 MYL2 ACTN2 ACTN2 FHOD3 FHOD3 PDGFRB PDGFRB ZMPSTE24 ZMPSTE24 PDCD4 PDCD4 SPRY1 SPRY1 ADRA1A ADRA1A TBX3 TBX3 HNRNPU HNRNPU FHL2 FHL2 MYH6 MYH6 SHOX2 SHOX2 ADPRHL1 ADPRHL1 MTOR MTOR LMNA LMNA NEBL NEBL BMPR1A BMPR1A NRAP NRAP ENSPTRP00000093588 ENSPTRP00000093588 ENSPTRP00000071419 ENSPTRP00000071419 CSRP3 CSRP3 ASB2 ASB2 MYLK3 MYLK3 MAP2K4 MAP2K4 TCAP TCAP ALPK2 ALPK2 TTN TTN JAG1 JAG1 CXADR CXADR CAV3 CAV3 SGCB SGCB MEF2A MEF2A TBX5 TBX5 LRRC10B LRRC10B MYO18B MYO18B ENSPTRP00000066578 ENSPTRP00000066578 TGFBR3 TGFBR3 ENSPTRP00000065655 ENSPTRP00000065655 C10H10orf113 C10H10orf113 ENSPTRP00000064416 ENSPTRP00000064416 SLC8A1 SLC8A1 MYH11 MYH11 CXADR-2 CXADR-2 ALPK3 ALPK3 SGCD SGCD OBSL1 OBSL1 MAML1 MAML1 PROX1 PROX1 CDK1 CDK1 AKAP13 AKAP13 LRRC10 LRRC10 NOTCH1 NOTCH1 PLEC PLEC NKX2-6 NKX2-6 HEY2 HEY2 ATG5 ATG5 BVES BVES SRF SRF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TBX18T-box transcription factor 18. (607 aa)
NKX2-5NKX2-5 isoform 1. (325 aa)
ISL1ISL LIM homeobox 1. (349 aa)
SORBS2Sorbin and SH3 domain containing 2. (1202 aa)
ENSPTRP00000072925annotation not available (372 aa)
NEBNEB isoform 5. (8417 aa)
GATA4GATA binding protein 4. (443 aa)
PDLIM5PDLIM5 isoform 14. (625 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
MYL2Myosin, light chain 2, regulatory, cardiac, slow. (166 aa)
ACTN2ACTN2 isoform 2. (894 aa)
FHOD3Formin homology 2 domain containing 3. (1622 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (480 aa)
PDCD4Programmed cell death 4 (Neoplastic transformation inhibitor). (469 aa)
SPRY1Sprouty homolog 1, antagonist of FGF signaling. (319 aa)
ADRA1AAdrenoceptor alpha 1A. (495 aa)
TBX3T-box transcription factor 3. (743 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U (Scaffold attachment factor A). (825 aa)
FHL2FHL2 isoform 4. (389 aa)
MYH6MYH6 isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2050 aa)
SHOX2SHOX2 isoform 2. (343 aa)
ADPRHL1ADPRHL1 isoform 2. (1673 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
LMNALMNA isoform 8; Belongs to the intermediate filament family. (664 aa)
NEBLNEBL isoform 5. (1014 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
NRAPNRAP isoform 1. (1730 aa)
ENSPTRP00000093588annotation not available (361 aa)
ENSPTRP00000071419annotation not available (371 aa)
CSRP3Cysteine and glycine rich protein 3. (194 aa)
ASB2Ankyrin repeat and SOCS box containing 2. (635 aa)
MYLK3MYLK3 isoform 1. (819 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (410 aa)
TCAPTCAP isoform 1. (167 aa)
ALPK2ALPK2 isoform 1. (2171 aa)
TTNTTN isoform 3. (32000 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
CXADRCXADR Ig-like cell adhesion molecule. (365 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
SGCBSarcoglycan beta. (320 aa)
MEF2AMyocyte enhancer factor 2A. (507 aa)
TBX5T-box transcription factor 5. (518 aa)
LRRC10BLeucine rich repeat containing 10B. (292 aa)
MYO18BMYO18B isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2550 aa)
ENSPTRP00000066578annotation not available (310 aa)
TGFBR3Transforming growth factor, beta receptor III. (861 aa)
ENSPTRP00000065655annotation not available (349 aa)
C10H10orf113C10orf113 isoform 2. (79 aa)
ENSPTRP00000064416annotation not available (502 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
MYH11MYH11 isoform 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2009 aa)
CXADR-2CXADR Ig-like cell adhesion molecule. (188 aa)
ALPK3ALPK3 isoform 1. (1901 aa)
SGCDSarcoglycan, delta (35kDa dystrophin-associated glycoprotein). (290 aa)
OBSL1OBSL1 isoform 6. (1895 aa)
MAML1MAML1 isoform 1. (1016 aa)
PROX1Prospero homeobox 1. (737 aa)
CDK1Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
AKAP13A-kinase anchoring protein 13. (2813 aa)
LRRC10Leucine rich repeat containing 10. (277 aa)
NOTCH1NOTCH1 isoform 1. (2555 aa)
PLECPLEC isoform 2. (4684 aa)
NKX2-6NKX2-6 isoform 1. (301 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif 2. (337 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
BVESBlood vessel epicardial substance. (360 aa)
SRFSerum response factor (C-fos serum response element-binding transcription factor). (508 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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