STRINGSTRING
FOXC1 FOXC1 ENSPTRP00000092784 ENSPTRP00000092784 NRG1 NRG1 MYH6 MYH6 COL11A1 COL11A1 MYH7 MYH7 MYL2 MYL2 RBPJ RBPJ BMP10 BMP10 MYL10-2 MYL10-2 ZFPM2 ZFPM2 TGFBR1 TGFBR1 MED1 MED1 NOG NOG SMAD7 SMAD7 SMAD4 SMAD4 TGFB1 TGFB1 LRP2 LRP2 MYL3 MYL3 TNNC1 TNNC1 HEG1 HEG1 EDNRA EDNRA ISL1 ISL1 PTCD2 PTCD2 HAND1 HAND1 NKX2-5 NKX2-5 DSP DSP HEY2 HEY2 MYL10 MYL10 CHD7 CHD7 FOXH1 FOXH1 ENG ENG NOTCH1 NOTCH1 TPM1 TPM1 TNNI3 TNNI3 PROX1 PROX1 FOXH1-2 FOXH1-2 FOXC2 FOXC2 ENSPTRP00000064416 ENSPTRP00000064416 RYR2 RYR2 PKP2 PKP2 MYBPC3 MYBPC3 FGFR2 FGFR2 BMPR1A BMPR1A TGFB2 TGFB2 TNNI1 TNNI1 POU4F1 POU4F1 TNNT2 TNNT2 DLL4 DLL4 TGFBR3 TGFBR3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FOXC1FOXC1 isoform 1. (550 aa)
ENSPTRP00000092784annotation not available (75 aa)
NRG1NRG1 isoform 3. (713 aa)
MYH6MYH6 isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2050 aa)
COL11A1Collagen type XI alpha 1 chain. (1818 aa)
MYH7Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1935 aa)
MYL2Myosin, light chain 2, regulatory, cardiac, slow. (166 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (500 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
MYL10-2MYL10 isoform 1. (226 aa)
ZFPM2ZFPM2 isoform 3. (1151 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1581 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
SMAD7Mothers against decapentaplegic homolog. (491 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
LRP2LRP2 isoform 1. (4655 aa)
MYL3Myosin, light chain 3, alkali ventricular, skeletal, slow. (224 aa)
TNNC1Troponin C1, slow skeletal and cardiac type. (161 aa)
HEG1HEG1 isoform 1. (1381 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
ISL1ISL LIM homeobox 1. (349 aa)
PTCD2Pentatricopeptide repeat domain 2. (388 aa)
HAND1Heart and neural crest derivatives expressed 1. (215 aa)
NKX2-5NKX2-5 isoform 1. (325 aa)
DSPDSP isoform 1. (2871 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif 2. (337 aa)
MYL10ADCY7 isoform 13. (226 aa)
CHD7CHD7 isoform 1. (2997 aa)
FOXH1FOXH1 isoform 1. (365 aa)
ENGENG isoform 1. (658 aa)
NOTCH1NOTCH1 isoform 1. (2555 aa)
TPM1TPM1 isoform 3; Belongs to the tropomyosin family. (326 aa)
TNNI3TNNI3 isoform 2. (169 aa)
PROX1Prospero homeobox 1. (737 aa)
FOXH1-2Forkhead box H1. (365 aa)
FOXC2Forkhead box C2 (MFH-1, mesenchyme forkhead 1). (501 aa)
ENSPTRP00000064416annotation not available (502 aa)
RYR2RYR2 isoform 1. (4941 aa)
PKP2PKP2 isoform 1. (837 aa)
MYBPC3Myosin binding protein C, cardiac. (1274 aa)
FGFR2Fibroblast growth factor receptor. (841 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
TNNI1Troponin I type 1 (Skeletal, slow). (187 aa)
POU4F1POU domain protein. (350 aa)
TNNT2Troponin T type 2 (Cardiac). (298 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (696 aa)
TGFBR3Transforming growth factor, beta receptor III. (861 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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