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WDPCP WDPCP HES5 HES5 REST REST GRXCR1 GRXCR1 TMC1 TMC1 CTHRC1 CTHRC1 LRRC1 LRRC1 ADGRV1 ADGRV1 SEC24B SEC24B PLS1 PLS1 SOD1 SOD1 USH1G USH1G SLC9A3R1 SLC9A3R1 MKS1 MKS1 FZD2 FZD2 NAGLU NAGLU STRC STRC TRIP11 TRIP11 ALG10 ALG10 PDZD7 PDZD7 ENSPTRP00000085692 ENSPTRP00000085692 ATP8B3 ATP8B3 SDC4 SDC4 HES5-2 HES5-2 PCDH15 PCDH15 PAFAH1B1 PAFAH1B1 CECR2 CECR2 IFT20 IFT20 MYO7A MYO7A LRTOMT LRTOMT SLC4A7 SLC4A7 CLRN1 CLRN1 ATP8B1 ATP8B1 WHRN WHRN TTC8 TTC8 LHFPL5 LHFPL5 LOC742658 LOC742658 HES1 HES1 CLRN2 CLRN2 CDH23 CDH23 SCRIB SCRIB TRIOBP TRIOBP TPRN TPRN SLITRK6 SLITRK6 IFT27 IFT27 PJVK PJVK USH1C USH1C GABRB2 GABRB2 SCRIB-2 SCRIB-2 TSHR TSHR PTPRQ PTPRQ GABRA5 GABRA5 KCNQ1 KCNQ1 TSKU TSKU GRXCR2 GRXCR2 IFT88 IFT88
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WDPCPWDPCP isoform 2. (746 aa)
HES5Hes family bHLH transcription factor 5. (165 aa)
RESTRE1 silencing transcription factor. (1097 aa)
GRXCR1Glutaredoxin and cysteine rich domain containing 1. (290 aa)
TMC1Transmembrane channel-like protein. (760 aa)
CTHRC1Collagen triple helix repeat containing 1. (243 aa)
LRRC1Leucine rich repeat containing 1. (524 aa)
ADGRV1ADGRV1 isoform 1; Belongs to the G-protein coupled receptor 2 family. (6306 aa)
SEC24BSEC24B isoform 1. (1286 aa)
PLS1Plastin 1 (I isoform). (629 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
USH1GUSH1 protein network component sans. (461 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (358 aa)
MKS1MKS transition zone complex subunit 1. (559 aa)
FZD2FZD2 isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (548 aa)
NAGLUN-acetyl-alpha-glucosaminidase. (743 aa)
STRCLOW QUALITY PROTEIN: stereocilin. (1772 aa)
TRIP11TRIP11 isoform 1. (1979 aa)
ALG10Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase. (473 aa)
PDZD7PDZD7 isoform 1. (1035 aa)
ENSPTRP00000085692annotation not available (679 aa)
ATP8B3Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1301 aa)
SDC4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (198 aa)
HES5-2Hes family bHLH transcription factor 5. (165 aa)
PCDH15Protocadherin related 15. (1954 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (413 aa)
CECR2CECR2 isoform 2. (1485 aa)
IFT20IFT20 isoform 5. (164 aa)
MYO7AMYO7A isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2222 aa)
LRTOMTTransmembrane O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones (By similarity). Required for auditory function (By similarity). Component of the cochlear hair cell's mechanotransduction (MET) machinery. Involved in the assembly of the asymmetric tip-link MET complex. Required for transportation of TMC1 and TMC2 proteins into the mechanically sensitive stereocilia of the hair cells. The function in MET is independent of the enzymatic activity (By similarity). (291 aa)
SLC4A7Anion exchange protein. (1259 aa)
CLRN1T0022075 isoform 1. (245 aa)
ATP8B1Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1251 aa)
WHRNWHRN isoform 2. (907 aa)
TTC8Tetratricopeptide repeat domain 8. (531 aa)
LHFPL5LHFPL tetraspan subfamily member 5. (219 aa)
LOC742658Stereocilin-like. (1726 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
CLRN2CLRN2 isoform 1. (232 aa)
CDH23CDH23 isoform 1. (3359 aa)
SCRIBSCRIB isoform 8. (959 aa)
TRIOBPTRIOBP isoform 1. (2139 aa)
TPRNTPRN isoform 2. (634 aa)
SLITRK6SLITRK6 isoform 1. (841 aa)
IFT27Intraflagellar transport 27 homolog. (186 aa)
PJVKDFNB59 isoform 1. (352 aa)
USH1CUSH1C isoform 4. (899 aa)
GABRB2Gamma-aminobutyric acid type A receptor beta2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (512 aa)
SCRIB-2Scribbled homolog. (1662 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
PTPRQPTPRQ isoform 2. (2158 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (676 aa)
TSKUTsukushi, small leucine rich proteoglycan. (353 aa)
GRXCR2GRXCR2 isoform 1. (248 aa)
IFT88Intraflagellar transport 88. (833 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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