31 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CABP4	Calcium binding protein 4. (275 aa)
	STAT3	Signal transducer and activator of transcription. (790 aa)
	ROM1-2	Retinal outer segment membrane protein 1. (351 aa)
	THRB	Thyroid hormone receptor beta. (476 aa)
	NTRK2	Tyrosine-protein kinase receptor. (838 aa)
	RPGRIP1	RPGR interacting protein 1. (1287 aa)
	TTC8	Tetratricopeptide repeat domain 8. (531 aa)
	ENSPTRP00000063978	annotation not available (224 aa)
	RORB	RAR related orphan receptor B. (482 aa)
	BBS4	Bardet-Biedl syndrome 4. (519 aa)
	TOPORS	Topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase. (1045 aa)
	USH1C	USH1C isoform 4. (899 aa)
	CRB2	CRB2 isoform 1. (1285 aa)
	NOTCH1	NOTCH1 isoform 1. (2555 aa)
	RP1	RP1 axonemal microtubule associated. (2156 aa)
	PDE6C	Phosphodiesterase. (858 aa)
	HCN1	HCN1 isoform 1. (886 aa)
	PROM1	PROM1 isoform 12. (865 aa)
	DSCAM	DS cell adhesion molecule. (2012 aa)
	BHLHE23	Basic helix-loop-helix family member e23. (241 aa)
	IHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
	SDK2	SDK2 isoform 1. (2172 aa)
	SOX9	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa)
	NAGLU	N-acetyl-alpha-glucosaminidase. (743 aa)
	RPGRIP1L	RPGRIP1L isoform 4. (1269 aa)
	SOX8	SOX8 isoform 1. (446 aa)
	NRL	Neural retina leucine zipper. (237 aa)
	THY1	Thy-1 cell surface antigen. (161 aa)
	ROM1	Retinal outer segment membrane protein 1. (351 aa)
	CNTF	Ciliary neurotrophic factor. (200 aa)
	GNAT2	G protein subunit alpha transducin 2. (354 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BBS4	RPGRIP1L	ENSPTRP00000057396	ENSPTRP00000013851	Bardet-Biedl syndrome 4.	RPGRIP1L isoform 4.	0.567
BBS4	TTC8	ENSPTRP00000057396	ENSPTRP00000066504	Bardet-Biedl syndrome 4.	Tetratricopeptide repeat domain 8.	0.998
CABP4	ROM1	ENSPTRP00000072433	ENSPTRP00000006484	Calcium binding protein 4.	Retinal outer segment membrane protein 1.	0.606
CABP4	ROM1-2	ENSPTRP00000072433	ENSPTRP00000085720	Calcium binding protein 4.	Retinal outer segment membrane protein 1.	0.606
CABP4	RPGRIP1	ENSPTRP00000072433	ENSPTRP00000073611	Calcium binding protein 4.	RPGR interacting protein 1.	0.494
CNTF	NTRK2	ENSPTRP00000006354	ENSPTRP00000077403	Ciliary neurotrophic factor.	Tyrosine-protein kinase receptor.	0.583
CNTF	STAT3	ENSPTRP00000006354	ENSPTRP00000091410	Ciliary neurotrophic factor.	Signal transducer and activator of transcription.	0.649
GNAT2	PDE6C	ENSPTRP00000001822	ENSPTRP00000029740	G protein subunit alpha transducin 2.	Phosphodiesterase.	0.947
GNAT2	ROM1	ENSPTRP00000001822	ENSPTRP00000006484	G protein subunit alpha transducin 2.	Retinal outer segment membrane protein 1.	0.594
GNAT2	ROM1-2	ENSPTRP00000001822	ENSPTRP00000085720	G protein subunit alpha transducin 2.	Retinal outer segment membrane protein 1.	0.594
IHH	SOX9	ENSPTRP00000022106	ENSPTRP00000016293	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	0.697
NOTCH1	PROM1	ENSPTRP00000036924	ENSPTRP00000027438	NOTCH1 isoform 1.	PROM1 isoform 12.	0.480
NOTCH1	SOX9	ENSPTRP00000036924	ENSPTRP00000016293	NOTCH1 isoform 1.	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	0.568
NOTCH1	STAT3	ENSPTRP00000036924	ENSPTRP00000091410	NOTCH1 isoform 1.	Signal transducer and activator of transcription.	0.556
NRL	ROM1	ENSPTRP00000010505	ENSPTRP00000006484	Neural retina leucine zipper.	Retinal outer segment membrane protein 1.	0.461
NRL	ROM1-2	ENSPTRP00000010505	ENSPTRP00000085720	Neural retina leucine zipper.	Retinal outer segment membrane protein 1.	0.461
NRL	RPGRIP1	ENSPTRP00000010505	ENSPTRP00000073611	Neural retina leucine zipper.	RPGR interacting protein 1.	0.559
NRL	TOPORS	ENSPTRP00000010505	ENSPTRP00000049387	Neural retina leucine zipper.	Topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase.	0.539
NTRK2	CNTF	ENSPTRP00000077403	ENSPTRP00000006354	Tyrosine-protein kinase receptor.	Ciliary neurotrophic factor.	0.583
PDE6C	GNAT2	ENSPTRP00000029740	ENSPTRP00000001822	Phosphodiesterase.	G protein subunit alpha transducin 2.	0.947