STRINGSTRING
HRC HRC FKBP1B FKBP1B PKD2 PKD2 CLIC2 CLIC2 JPH1 JPH1 ASPH ASPH JPH3 JPH3 TRDN TRDN JPH4 JPH4 JPH2 JPH2 GSTO1 GSTO1 ENSPTRP00000063671 ENSPTRP00000063671 CLIC2-2 CLIC2-2 PDE4D PDE4D DMD DMD PLN PLN SRI SRI SRI-2 SRI-2 ENSPTRP00000082718 ENSPTRP00000082718 CALM1 CALM1 DMD-2 DMD-2 ENSPTRP00000085680 ENSPTRP00000085680 SELENON SELENON CAMK2D CAMK2D ENSPTRP00000090392 ENSPTRP00000090392 NOS1 NOS1 CK820_G0029100 CK820_G0029100 CALM3 CALM3 PRKACA PRKACA JSRP1 JSRP1 AKAP6 AKAP6 CASQ2 CASQ2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HRCHRC isoform 2. (693 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (968 aa)
CLIC2Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (247 aa)
JPH1Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (661 aa)
ASPHASPH isoform 1. (762 aa)
JPH3Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (748 aa)
TRDNTRDN isoform 1. (730 aa)
JPH4Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (628 aa)
JPH2Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (696 aa)
GSTO1Glutathione S-transferase omega 1. (241 aa)
ENSPTRP00000063671annotation not available (122 aa)
CLIC2-2Chloride intracellular channel 2. (247 aa)
PDE4DPhosphodiesterase. (809 aa)
DMDDMD isoform 3. (3685 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
SRISRI isoform 1. (205 aa)
SRI-2SRI isoform 5. (237 aa)
ENSPTRP00000082718annotation not available (235 aa)
CALM1CALM1 isoform 3; Belongs to the calmodulin family. (150 aa)
DMD-2Dystrophin. (643 aa)
ENSPTRP00000085680annotation not available (88 aa)
SELENONT0161445 isoform 2. (581 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (446 aa)
ENSPTRP00000090392annotation not available (93 aa)
NOS1Nitric oxide synthase 1. (1468 aa)
CK820_G0029100SRI isoform 2. (98 aa)
CALM3Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family. (149 aa)
PRKACAPRKACA isoform 7; Belongs to the protein kinase superfamily. (289 aa)
JSRP1Junctional sarcoplasmic reticulum protein 1. (331 aa)
AKAP6A-kinase anchoring protein 6. (2319 aa)
CASQ2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (399 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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