STRINGSTRING
SMAD5 SMAD5 SKI SKI DHRS3 DHRS3 WASF2 WASF2 ENSPTRP00000000715 ENSPTRP00000000715 MATN1 MATN1 ECM1 ECM1 THBS3 THBS3 BGLAP BGLAP DDR2 DDR2 MYOC MYOC PAPPA2 PAPPA2 PTPRC PTPRC FGFR2 FGFR2 LTBP3 LTBP3 FGF4 FGF4 INPPL1 INPPL1 SERPINH1 SERPINH1 ZBTB16 ZBTB16 WNT1 WNT1 NAB2 NAB2 EPYC EPYC SH2B3 SH2B3 TNFSF11 TNFSF11 MMP14 MMP14 BMP4 BMP4 TGFB3 TGFB3 TRIP11 TRIP11 PPIB PPIB ADAMTS7 ADAMTS7 XYLT1 XYLT1 SMPD3 SMPD3 ZFPM1 ZFPM1 RPL13 RPL13 SPNS2 SPNS2 TP53 TP53 TMEM107 TMEM107 CTC1 CTC1 MED1 MED1 HOXB4 HOXB4 PHOSPHO1 PHOSPHO1 COL1A1 COL1A1 CHAD CHAD AXIN2 AXIN2 SOX9 SOX9 ACP5 ACP5 TGFB1 TGFB1 MEGF8 MEGF8 INSIG2 INSIG2 COL3A1 COL3A1 NAB1 NAB1 IHH IHH NPPC NPPC BMP2 BMP2 PAX1 PAX1 TGM2 TGM2 CBS CBS LRP5L LRP5L EP300 EP300 LTF LTF PLXNB1 PLXNB1 RHOA RHOA IFT80 IFT80 NSD2 NSD2 KIT KIT BMPR1B BMPR1B PITX2 PITX2 SMAD1 SMAD1 SRD5A1 SRD5A1 NEUROG1 NEUROG1 CDX1 CDX1 BMP6 BMP6 MAPK14 MAPK14 SRF SRF PEX7 PEX7 TBXT TBXT SNX10 SNX10 HOXA11 HOXA11 SFRP4 SFRP4 GLI3 GLI3 SBDS SBDS DLX5 DLX5 LRRC17 LRRC17 INSIG1 INSIG1 STC1 STC1 EXT1 EXT1 CCN4 CCN4 CER1 CER1 CK820_G0008402 CK820_G0008402 NPR2 NPR2 OGN OGN COL27A1 COL27A1 ENG ENG MIGA2 MIGA2 PHEX PHEX ATP6AP1 ATP6AP1 AKAP13 AKAP13 COL2A1 COL2A1 BGN BGN COL13A1 COL13A1 CCDC154 CCDC154 FLI1 FLI1 ABI1 ABI1 AMER1 AMER1 ATG9B ATG9B TSKU TSKU TWIST1 TWIST1 IFITM5 IFITM5 BMPR2 BMPR2 SP5 SP5 SEMA4D SEMA4D BNC2 BNC2 FREM1 FREM1 RIPPLY2 RIPPLY2 PTPN6 PTPN6 NOTUM NOTUM RARA RARA GP1BA GP1BA EVC EVC MSX1 MSX1 PHOSPHO2 PHOSPHO2 GP1BB GP1BB COMP COMP P3H1 P3H1 LEPR LEPR GNAS GNAS GP9 GP9 TTC9 TTC9 HAS2 HAS2 ADAMTS12 ADAMTS12 PTPN11 PTPN11 MPIG6B MPIG6B MAP2K6 MAP2K6 ENSPTRP00000062265 ENSPTRP00000062265 SH3PXD2B SH3PXD2B THPO THPO LOC104003639 LOC104003639 FLNA FLNA ATF2 ATF2 FOXN3 FOXN3 ENSPTRP00000063945 ENSPTRP00000063945 FOXC1 FOXC1 RUNX2 RUNX2 ENSPTRP00000066121 ENSPTRP00000066121 CK820_G0008402-2 CK820_G0008402-2 MEIS1 MEIS1 TMEM107-2 TMEM107-2 LOC736481 LOC736481 ENSPTRP00000067174 ENSPTRP00000067174 TULP3 TULP3 PAPSS2 PAPSS2 IGF1 IGF1 LRP5 LRP5 GLG1 GLG1 ENSPTRP00000070794 ENSPTRP00000070794 GP5 GP5 ASXL1 ASXL1 IFT172 IFT172 IMPAD1 IMPAD1 PIP4K2A PIP4K2A EBP EBP TMEM119 TMEM119 LEP LEP PTPN11-2 PTPN11-2 SCX SCX SULF1 SULF1 ENSPTRP00000073786 ENSPTRP00000073786 TIFAB TIFAB MEF2D MEF2D RAB23 RAB23 GHR GHR ALPL ALPL ITGB6 ITGB6 MAPK11 MAPK11 ENSPTRP00000074763 ENSPTRP00000074763 FOXP1 FOXP1 TGFBR2 TGFBR2 MMP16 MMP16 DCANP1 DCANP1 ENSPTRP00000075468 ENSPTRP00000075468 FGF8 FGF8 MMP13 MMP13 SRC SRC ENSPTRP00000077211 ENSPTRP00000077211 ENSPTRP00000077262 ENSPTRP00000077262 PAFAH1B1 PAFAH1B1 LOC107971060 LOC107971060 ACCS ACCS BBX BBX DYM DYM ZMPSTE24 ZMPSTE24 ENSPTRP00000080470 ENSPTRP00000080470 CYP26B1 CYP26B1 BMP4-2 BMP4-2 ANXA6 ANXA6 CITED2 CITED2 SULF2 SULF2 ENSPTRP00000081784 ENSPTRP00000081784 ZNF385A ZNF385A RARB RARB ENSPTRP00000083030 ENSPTRP00000083030 RARG RARG SCUBE2 SCUBE2 PLS3 PLS3 ANXA2 ANXA2 ENSPTRP00000084922 ENSPTRP00000084922 SRD5A2 SRD5A2 LOC744101 LOC744101 TRPV4 TRPV4 RANBP3L RANBP3L GPR68 GPR68 ACTN3 ACTN3 VPS33B VPS33B TFAP2A TFAP2A MBTPS2 MBTPS2 TMEM38B TMEM38B DCHS1 DCHS1 FGFR3 FGFR3 SLC38A10 SLC38A10 TRIM45 TRIM45 ENSPTRP00000090344 ENSPTRP00000090344 MEF2C MEF2C PDGFC PDGFC CK820_G0030361 CK820_G0030361 FGF18 FGF18 LRRK1 LRRK1 SHOX2 SHOX2 ENSPTRP00000092364 ENSPTRP00000092364 ATG9A ATG9A RYR1 RYR1 ENSPTRP00000092702 ENSPTRP00000092702 MCPH1 MCPH1 OSR2 OSR2 OSTN OSTN SLC10A7 SLC10A7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMAD5Mothers against decapentaplegic homolog. (465 aa)
SKIV-ski sarcoma viral oncogene homolog (Avian). (736 aa)
DHRS3Dehydrogenase/reductase (SDR family) member 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
WASF2WAS protein family, member 2. (498 aa)
ENSPTRP00000000715Wiskott-Aldrich syndrome protein family member 2-like. (492 aa)
MATN1MATN1 isoform 1. (496 aa)
ECM1Extracellular matrix protein 1. (540 aa)
THBS3Thrombospondin 3. (956 aa)
BGLAPOsteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. (100 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (855 aa)
MYOCMYOC isoform 1. (504 aa)
PAPPA2PAPPA2 isoform 1. (1791 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1306 aa)
FGFR2Fibroblast growth factor receptor. (841 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1297 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
INPPL1Inositol polyphosphate phosphatase-like 1. (1258 aa)
SERPINH1Serpin peptidase inhibitor, clade H (Heat shock protein 47), member 1, (Collagen binding protein 1); Belongs to the serpin family. (418 aa)
ZBTB16Zinc finger and BTB domain containing 16. (673 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
NAB2NGFI-A binding protein 2 (EGR1 binding protein 2). (525 aa)
EPYCEPYC isoform 1. (322 aa)
SH2B3SH2B adaptor protein 3. (575 aa)
TNFSF11Tumor necrosis factor ligand superfamily member. (317 aa)
MMP14Matrix metallopeptidase 14. (582 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
TRIP11TRIP11 isoform 1. (1979 aa)
PPIBPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
ADAMTS7ADAMTS7 isoform 1. (932 aa)
XYLT1Xylosyltransferase 1; Catalyzes the first step in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans, such as DCN. Transfers D- xylose from UDP-D-xylose to specific serine residues of the core protein. Required for normal maturation of chondrocytes during bone development, normal onset of ossification and normal embryonic and postnatal skeleton development, especially of the long bones. (958 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (655 aa)
ZFPM1ZFPM1 isoform 1. (974 aa)
RPL1360S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family. (211 aa)
SPNS2Sphingolipid transporter 2. (548 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
TMEM107Transmembrane protein 107. (146 aa)
CTC1CTS telomere maintenance complex component 1. (1159 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1581 aa)
HOXB4HOXB4 isoform 1. (251 aa)
PHOSPHO1Phosphoethanolamine/phosphocholine phosphatase. (267 aa)
COL1A1Collagen type I alpha 1 chain. (1464 aa)
CHADCHAD isoform 1. (359 aa)
AXIN2AXIN2 isoform 1. (843 aa)
SOX9Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa)
ACP5Tartrate-resistant acid phosphatase type 5. (325 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
MEGF8Multiple EGF like domains 8. (2842 aa)
INSIG2Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
NAB1NGFI-A binding protein 1 (EGR1 binding protein 1). (487 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
NPPCNatriuretic peptide C. (126 aa)
BMP2Bone morphogenetic protein 2. (398 aa)
PAX1PAX1 isoform 1. (457 aa)
TGM2Transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase). (687 aa)
CBSCystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (551 aa)
LRP5LLDL receptor related protein 5 like. (252 aa)
EP300E1A binding protein p300. (2175 aa)
LTFLactotransferrin; Belongs to the transferrin family. (711 aa)
PLXNB1PLXNB1 isoform 1. (2135 aa)
RHOARas homolog family member A. (193 aa)
IFT80Intraflagellar transport protein 80 homolog. (763 aa)
NSD2Nuclear receptor binding SET domain protein 2. (1365 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
PITX2Homeobox protein. (324 aa)
SMAD1Mothers against decapentaplegic homolog. (469 aa)
SRD5A13-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (259 aa)
NEUROG1NEUROG1 isoform 1. (237 aa)
CDX1CDX1 isoform 1. (265 aa)
BMP6Bone morphogenetic protein 6. (512 aa)
MAPK14Mitogen-activated protein kinase 14; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are a [...] (360 aa)
SRFSerum response factor (C-fos serum response element-binding transcription factor). (508 aa)
PEX7Peroxisomal biogenesis factor 7. (323 aa)
TBXTT-box transcription factor T. (435 aa)
SNX10Sorting nexin 10. (201 aa)
HOXA11HOXA11 isoform 2. (313 aa)
SFRP4SFRP4 isoform 1. (368 aa)
GLI3Transcriptional repressor GLI3R; Has a dual function as a transcriptional activator and a repressor of the sonic hedgehog (Shh) pathway, and plays a role in limb development. The full-length GLI3 form (GLI3FL) after phosphorylation and nuclear translocation, acts as an activator (GLI3A) while GLI3R, its C-terminally truncated form, acts as a repressor. A proper balance between the GLI3 activator and the repressor GLI3R, rather than the repressor gradient itself or the activator/repressor ratio gradient, specifies limb digit number and identity. In concert with TRPS1, plays a role in re [...] (1580 aa)
SBDSShwachman-Bodian-Diamond syndrome. (250 aa)
DLX5Distal-less homeobox 5. (289 aa)
LRRC17Leucine rich repeat containing 17. (441 aa)
INSIG1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (277 aa)
STC1Stanniocalcin 1. (247 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
CCN4WISP1 isoform 1. (367 aa)
CER1CER1 isoform 1. (267 aa)
CK820_G0008402Annexin. (233 aa)
NPR2Guanylate cyclase. (1047 aa)
OGNOGN isoform 2. (298 aa)
COL27A1COL27A1 isoform 1. (1860 aa)
ENGENG isoform 1. (658 aa)
MIGA2Family with sequence similarity 73, member B. (593 aa)
PHEXPhosphate regulating endopeptidase homolog X-linked. (749 aa)
ATP6AP1ATPase H+ transporting accessory protein 1. (470 aa)
AKAP13A-kinase anchoring protein 13. (2813 aa)
COL2A1Collagen type II alpha 1 chain. (1487 aa)
BGNBiglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (376 aa)
COL13A1Collagen type XIII alpha 1 chain. (717 aa)
CCDC154Coiled-coil domain containing 154. (522 aa)
FLI1Fli-1 proto-oncogene, ETS transcription factor. (452 aa)
ABI1Abl interactor 1. (508 aa)
AMER1APC membrane recruitment protein 1. (805 aa)
ATG9BAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (921 aa)
TSKUTsukushi, small leucine rich proteoglycan. (353 aa)
TWIST1TWIST1 isoform 2. (163 aa)
IFITM5Interferon induced transmembrane protein 5. (132 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (891 aa)
SP5Sp5 transcription factor. (398 aa)
SEMA4DSEMA4D isoform 13; Belongs to the semaphorin family. (862 aa)
BNC2BNC2 isoform 3. (1099 aa)
FREM1FREM1 isoform 1. (2179 aa)
RIPPLY2Ripply transcriptional repressor 2. (128 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
NOTUMNotum, palmitoleoyl-protein carboxylesterase. (496 aa)
RARARARA isoform 4. (624 aa)
GP1BAGP1BA isoform 1. (653 aa)
EVCEVC isoform 1. (991 aa)
MSX1Homeobox protein MSX-1; Acts as a transcriptional repressor. May play a role in limb- pattern formation. Acts in cranofacial development and specifically in odontogenesis (By similarity). (303 aa)
PHOSPHO2Phosphatase, orphan 2. (241 aa)
GP1BBGlycoprotein Ib (Platelet), beta polypeptide. (206 aa)
COMPCartilage oligomeric matrix protein. (757 aa)
P3H1P3H1 isoform 6. (797 aa)
LEPRLeptin receptor. (1165 aa)
GNASGNAS isoform 19. (1042 aa)
GP9Glycoprotein IX platelet. (177 aa)
TTC9Tetratricopeptide repeat domain 9. (222 aa)
HAS2Hyaluronan synthase 2. (554 aa)
ADAMTS12ADAM metallopeptidase with thrombospondin type 1 motif 12. (1509 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
MPIG6BMPIG6B isoform 11. (242 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (339 aa)
ENSPTRP00000062265annotation not available (82 aa)
SH3PXD2BSH3 and PX domains 2B. (911 aa)
THPOTHPO isoform 1. (353 aa)
LOC104003639Guanine nucleotide-binding protein G(s) subunit alpha. (245 aa)
FLNAFLNA isoform 8. (2711 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
FOXN3FOXN3 isoform 2. (490 aa)
ENSPTRP00000063945annotation not available (476 aa)
FOXC1FOXC1 isoform 1. (550 aa)
RUNX2Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (569 aa)
ENSPTRP00000066121annotation not available (305 aa)
CK820_G0008402-2Annexin. (325 aa)
MEIS1MEIS1 isoform 7. (465 aa)
TMEM107-2Transmembrane protein 107. (140 aa)
LOC736481Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (400 aa)
ENSPTRP00000067174annotation not available (502 aa)
TULP3TULP3 isoform 3; Belongs to the TUB family. (501 aa)
PAPSS2PAPSS2 isoform 2. (619 aa)
IGF1Insulin-like growth factor 1 (Somatomedin C). (196 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1606 aa)
GLG1Golgi glycoprotein 1. (1203 aa)
ENSPTRP00000070794annotation not available (426 aa)
GP5GP5 isoform 1. (560 aa)
ASXL1ASXL transcriptional regulator 1. (1548 aa)
IFT172Intraflagellar transport 172 homolog. (1767 aa)
IMPAD1Inositol monophosphatase domain containing 1. (388 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase, type II, alpha. (406 aa)
EBPEmopamil binding protein (Sterol isomerase). (230 aa)
TMEM119Transmembrane protein 119. (283 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (167 aa)
PTPN11-2Protein tyrosine phosphatase non-receptor type 11. (579 aa)
SCXScleraxis bHLH transcription factor. (201 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (901 aa)
ENSPTRP00000073786annotation not available (205 aa)
TIFABTIFAB isoform 1. (161 aa)
MEF2DMyocyte enhancer factor 2D. (521 aa)
RAB23RAB23, member RAS oncogene family. (237 aa)
GHRGrowth hormone receptor. (645 aa)
ALPLAlkaline phosphatase. (524 aa)
ITGB6ITGB6 isoform 3. (701 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
ENSPTRP00000074763annotation not available (520 aa)
FOXP1FOXP1 isoform 2. (693 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (581 aa)
MMP16Matrix metallopeptidase 16 (Membrane-inserted). (609 aa)
DCANP1LOW QUALITY PROTEIN: dendritic cell nuclear protein 1. (237 aa)
ENSPTRP00000075468annotation not available (220 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
MMP13Matrix metallopeptidase 13. (498 aa)
SRCTyrosine-protein kinase. (542 aa)
ENSPTRP00000077211annotation not available (269 aa)
ENSPTRP00000077262annotation not available (314 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (413 aa)
LOC107971060SRD5A1 isoform 2. (141 aa)
ACCSExostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (891 aa)
BBXBBX isoform 7. (941 aa)
DYMDYM isoform 2. (669 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (480 aa)
ENSPTRP00000080470annotation not available (87 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
BMP4-2Bone morphogenetic protein 4. (408 aa)
ANXA6Annexin. (788 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
SULF2Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (870 aa)
ENSPTRP00000081784annotation not available (218 aa)
ZNF385AZinc finger protein 385A. (414 aa)
RARBRetinoic acid receptor, beta. (448 aa)
ENSPTRP00000083030annotation not available (225 aa)
RARGRetinoic acid receptor, gamma. (456 aa)
SCUBE2SCUBE2 isoform 2. (996 aa)
PLS3PLS3 isoform 3. (639 aa)
ANXA2Annexin. (357 aa)
ENSPTRP00000084922annotation not available (593 aa)
SRD5A23-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (254 aa)
LOC74410160S ribosomal protein L13 pseudogene. (202 aa)
TRPV4Transient receptor potential cation channel, subfamily V, member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa)
RANBP3LRAN binding protein 3 like. (490 aa)
GPR68GPR68 isoform 1; Belongs to the G-protein coupled receptor 1 family. (375 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (944 aa)
VPS33BVPS33B late endosome and lysosome associated; Belongs to the STXBP/unc-18/SEC1 family. (617 aa)
TFAP2ATranscription factor AP-2 alpha. (439 aa)
MBTPS2Membrane-bound transcription factor peptidase, site 2. (527 aa)
TMEM38BTransmembrane protein 38B. (297 aa)
DCHS1DCHS1 isoform 1. (3298 aa)
FGFR3Fibroblast growth factor receptor. (808 aa)
SLC38A10Solute carrier family 38, member 10. (1120 aa)
TRIM45Tripartite motif containing 45. (580 aa)
ENSPTRP00000090344annotation not available (218 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
PDGFCPlatelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa)
CK820_G0030361RYR1 isoform 5. (4901 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
LRRK1Leucine-rich repeat kinase 1. (2015 aa)
SHOX2SHOX2 isoform 2. (343 aa)
ENSPTRP00000092364annotation not available (574 aa)
ATG9AAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (869 aa)
RYR1RYR1 isoform 3. (5037 aa)
ENSPTRP00000092702annotation not available (482 aa)
MCPH1Microcephalin; Implicated in chromosome condensation and DNA damage induced cellular responses. May play a role in neurogenesis and regulation of the size of the cerebral cortex (By similarity). (851 aa)
OSR2Protein odd-skipped-related 2 isoform X4. (433 aa)
OSTNOSTN isoform 2. (133 aa)
SLC10A7Sodium/bile acid cotransporter; Does not show transport activity towards bile acids or steroid sulfates; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. (358 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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