STRINGSTRING
TGFB3 TGFB3 JAK2 JAK2 BMP4-2 BMP4-2 PPARG PPARG TGFBR1 TGFBR1 DAB2 DAB2 NUP93 NUP93 ENSPTRP00000064416 ENSPTRP00000064416 BMPR2 BMPR2 RBPMS RBPMS KIAA0319 KIAA0319 BMP6 BMP6 BMP2 BMP2 TGFB1 TGFB1 SMAD4 SMAD4 BMP4 BMP4 BMPR1A BMPR1A NODAL NODAL PARP1 PARP1 SH2B1 SH2B1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
JAK2Tyrosine-protein kinase. (1143 aa)
BMP4-2Bone morphogenetic protein 4. (408 aa)
PPARGPeroxisome proliferator-activated receptor gamma isoform X2. (505 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
DAB2Disabled homolog 2, mitogen-responsive phosphoprotein. (770 aa)
NUP93Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (880 aa)
ENSPTRP00000064416annotation not available (502 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (891 aa)
RBPMSRNA binding protein, mRNA processing factor. (219 aa)
KIAA0319KIAA0319 isoform 5. (1072 aa)
BMP6Bone morphogenetic protein 6. (512 aa)
BMP2Bone morphogenetic protein 2. (398 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
NODALNODAL isoform 2. (347 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
SH2B1SH2B adaptor protein 1. (756 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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