STRINGSTRING
CACNA1C CACNA1C JPH4 JPH4 CACNB3 CACNB3 TRPV5 TRPV5 ADRA1A ADRA1A ENSPTRP00000078515 ENSPTRP00000078515 CACNA2D1 CACNA2D1 TRPM1 TRPM1 RYR2 RYR2 SLC8A1 SLC8A1 JPH2 JPH2 BCL2 BCL2 JPH3 JPH3 JPH1 JPH1 BAK1 BAK1 TRPV5-2 TRPV5-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa)
JPH4Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (628 aa)
CACNB3Calcium channel, voltage-dependent, beta 3 subunit. (487 aa)
TRPV5Transient receptor potential cation channel subfamily V member 5. (732 aa)
ADRA1AAdrenoceptor alpha 1A. (495 aa)
ENSPTRP00000078515annotation not available (198 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1103 aa)
TRPM1Transient receptor potential cation channel subfamily M member 1. (1642 aa)
RYR2RYR2 isoform 1. (4941 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
JPH2Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (696 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
JPH3Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (748 aa)
JPH1Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (661 aa)
BAK1BCL2-antagonist/killer 1. (211 aa)
TRPV5-2Transient receptor potential cation channel subfamily V member 5; Belongs to the transient receptor (TC 1.A.4) family. (732 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.