13 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
	FGFR2	Fibroblast growth factor receptor. (841 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	BMP4-2	Bone morphogenetic protein 4. (408 aa)
	HOXB13	HOXB13 isoform 1. (284 aa)
	HOXD13	HOXD13 isoform 1. (344 aa)
	ESR1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
	HOXA13-2	HOXA13 isoform 1. (388 aa)
	FRS2	Fibroblast growth factor receptor substrate 2. (521 aa)
	FEM1B	FEM1B isoform 1. (627 aa)
	NKX3-1	NKX3-1 isoform 1. (234 aa)
	SFRP1	Secreted frizzled-related protein 1. (314 aa)
	HOXA13	Homeobox A13. (388 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	FGFR2	ENSPTRP00000010780	ENSPTRP00000005308	Bone morphogenetic protein 4.	Fibroblast growth factor receptor.	0.492
BMP4	SHH	ENSPTRP00000010780	ENSPTRP00000075730	Bone morphogenetic protein 4.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.720
BMP4-2	FGFR2	ENSPTRP00000080656	ENSPTRP00000005308	Bone morphogenetic protein 4.	Fibroblast growth factor receptor.	0.492
BMP4-2	SHH	ENSPTRP00000080656	ENSPTRP00000075730	Bone morphogenetic protein 4.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.720
ESR1	FGFR2	ENSPTRP00000031932	ENSPTRP00000005308	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Fibroblast growth factor receptor.	0.581
ESR1	SHH	ENSPTRP00000031932	ENSPTRP00000075730	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.489
FGFR2	BMP4	ENSPTRP00000005308	ENSPTRP00000010780	Fibroblast growth factor receptor.	Bone morphogenetic protein 4.	0.492
FGFR2	BMP4-2	ENSPTRP00000005308	ENSPTRP00000080656	Fibroblast growth factor receptor.	Bone morphogenetic protein 4.	0.492
FGFR2	ESR1	ENSPTRP00000005308	ENSPTRP00000031932	Fibroblast growth factor receptor.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.581
FGFR2	FRS2	ENSPTRP00000005308	ENSPTRP00000090329	Fibroblast growth factor receptor.	Fibroblast growth factor receptor substrate 2.	0.929
FGFR2	SHH	ENSPTRP00000005308	ENSPTRP00000075730	Fibroblast growth factor receptor.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.545
FRS2	FGFR2	ENSPTRP00000090329	ENSPTRP00000005308	Fibroblast growth factor receptor substrate 2.	Fibroblast growth factor receptor.	0.929
HOXD13	SHH	ENSPTRP00000021643	ENSPTRP00000075730	HOXD13 isoform 1.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.718
SFRP1	SHH	ENSPTRP00000053182	ENSPTRP00000075730	Secreted frizzled-related protein 1.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.485
SHH	BMP4	ENSPTRP00000075730	ENSPTRP00000010780	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Bone morphogenetic protein 4.	0.720
SHH	BMP4-2	ENSPTRP00000075730	ENSPTRP00000080656	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Bone morphogenetic protein 4.	0.720
SHH	ESR1	ENSPTRP00000075730	ENSPTRP00000031932	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.489
SHH	FGFR2	ENSPTRP00000075730	ENSPTRP00000005308	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Fibroblast growth factor receptor.	0.545
SHH	HOXD13	ENSPTRP00000075730	ENSPTRP00000021643	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	HOXD13 isoform 1.	0.718
SHH	SFRP1	ENSPTRP00000075730	ENSPTRP00000053182	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Secreted frizzled-related protein 1.	0.485