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FGFR2 | Fibroblast growth factor receptor. (841 aa) | ||||
BMP4 | Bone morphogenetic protein 4. (408 aa) | ||||
TBX2 | T-box transcription factor 2. (712 aa) | ||||
GLI3 | Transcriptional repressor GLI3R; Has a dual function as a transcriptional activator and a repressor of the sonic hedgehog (Shh) pathway, and plays a role in limb development. The full-length GLI3 form (GLI3FL) after phosphorylation and nuclear translocation, acts as an activator (GLI3A) while GLI3R, its C-terminally truncated form, acts as a repressor. A proper balance between the GLI3 activator and the repressor GLI3R, rather than the repressor gradient itself or the activator/repressor ratio gradient, specifies limb digit number and identity. In concert with TRPS1, plays a role in re [...] (1580 aa) | ||||
NRG3 | NRG3 isoform 3. (721 aa) | ||||
FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) | ||||
TBX3 | T-box transcription factor 3. (743 aa) | ||||
BMP4-2 | Bone morphogenetic protein 4. (408 aa) |