node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AR | CTNNB1 | ENSPTRP00000076864 | ENSPTRP00000044466 | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | Catenin (Cadherin-associated protein), beta 1, 88kDa. | 0.960 |
AR | NKX3-1 | ENSPTRP00000076864 | ENSPTRP00000081164 | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | NKX3-1 isoform 1. | 0.726 |
AR | WDR77 | ENSPTRP00000076864 | ENSPTRP00000001898 | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | Methylosome protein 50. | 0.450 |
CDKN1B | CTNNB1 | ENSPTRP00000008044 | ENSPTRP00000044466 | Cyclin-dependent kinase inhibitor 1B (P27, Kip1). | Catenin (Cadherin-associated protein), beta 1, 88kDa. | 0.461 |
CTNNB1 | AR | ENSPTRP00000044466 | ENSPTRP00000076864 | Catenin (Cadherin-associated protein), beta 1, 88kDa. | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | 0.960 |
CTNNB1 | CDKN1B | ENSPTRP00000044466 | ENSPTRP00000008044 | Catenin (Cadherin-associated protein), beta 1, 88kDa. | Cyclin-dependent kinase inhibitor 1B (P27, Kip1). | 0.461 |
CTNNB1 | NOTCH1 | ENSPTRP00000044466 | ENSPTRP00000036924 | Catenin (Cadherin-associated protein), beta 1, 88kDa. | NOTCH1 isoform 1. | 0.784 |
CTNNB1 | SHH | ENSPTRP00000044466 | ENSPTRP00000075730 | Catenin (Cadherin-associated protein), beta 1, 88kDa. | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. | 0.720 |
CTNNB1 | STK11 | ENSPTRP00000044466 | ENSPTRP00000017320 | Catenin (Cadherin-associated protein), beta 1, 88kDa. | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. | 0.474 |
NKX3-1 | AR | ENSPTRP00000081164 | ENSPTRP00000076864 | NKX3-1 isoform 1. | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | 0.726 |
NOTCH1 | CTNNB1 | ENSPTRP00000036924 | ENSPTRP00000044466 | NOTCH1 isoform 1. | Catenin (Cadherin-associated protein), beta 1, 88kDa. | 0.784 |
NOTCH1 | SHH | ENSPTRP00000036924 | ENSPTRP00000075730 | NOTCH1 isoform 1. | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. | 0.482 |
NOTCH1 | STK11 | ENSPTRP00000036924 | ENSPTRP00000017320 | NOTCH1 isoform 1. | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. | 0.452 |
SHH | CTNNB1 | ENSPTRP00000075730 | ENSPTRP00000044466 | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. | Catenin (Cadherin-associated protein), beta 1, 88kDa. | 0.720 |
SHH | NOTCH1 | ENSPTRP00000075730 | ENSPTRP00000036924 | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. | NOTCH1 isoform 1. | 0.482 |
STK11 | CTNNB1 | ENSPTRP00000017320 | ENSPTRP00000044466 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. | Catenin (Cadherin-associated protein), beta 1, 88kDa. | 0.474 |
STK11 | NOTCH1 | ENSPTRP00000017320 | ENSPTRP00000036924 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. | NOTCH1 isoform 1. | 0.452 |
WDR77 | AR | ENSPTRP00000001898 | ENSPTRP00000076864 | Methylosome protein 50. | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | 0.450 |