27 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CDC73	Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog. (531 aa)
	PAX2	PAX2 isoform 1. (417 aa)
	EYA2	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (538 aa)
	PAF1	Paf1, RNA polymerase II associated factor, homolog. (533 aa)
	NODAL	NODAL isoform 2. (347 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	RTF1	Rtf1, Paf1/RNA polymerase II complex component, homolog. (710 aa)
	LEO1	Leo1, Paf1/RNA polymerase II complex component, homolog. (666 aa)
	TBX6	T-box transcription factor 6. (443 aa)
	GATA6	GATA binding protein 6. (594 aa)
	SIX2	SIX homeobox 2. (291 aa)
	EOMES	EOMES isoform 2. (704 aa)
	SMAD1	Mothers against decapentaplegic homolog. (469 aa)
	SFRP2	Secreted frizzled-related protein 2. (295 aa)
	HOXA11	HOXA11 isoform 2. (313 aa)
	SOX17	SOX17 isoform 1. (416 aa)
	EYA1	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
	KLF4	Kruppel-like factor 4 (Gut). (479 aa)
	CTR9	Ctr9, Paf1/RNA polymerase II complex component, homolog. (1173 aa)
	ETS2	Protein C-ets-2; Transcription factor; Belongs to the ETS family. (469 aa)
	CTNNB1	Catenin (Cadherin-associated protein), beta 1, 88kDa. (781 aa)
	SOX2	SRY-box transcription factor 2. (319 aa)
	WNT3A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	FOXC2	Forkhead box C2 (MFH-1, mesenchyme forkhead 1). (501 aa)
	ETV2	ETV2 isoform 5. (370 aa)
	ENSPTRP00000077262	annotation not available (314 aa)
	BMP4-2	Bone morphogenetic protein 4. (408 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	CTNNB1	ENSPTRP00000010780	ENSPTRP00000044466	Bone morphogenetic protein 4.	Catenin (Cadherin-associated protein), beta 1, 88kDa.	0.551
BMP4	EYA1	ENSPTRP00000010780	ENSPTRP00000034805	Bone morphogenetic protein 4.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.411
BMP4	GATA6	ENSPTRP00000010780	ENSPTRP00000016858	Bone morphogenetic protein 4.	GATA binding protein 6.	0.546
BMP4	KLF4	ENSPTRP00000010780	ENSPTRP00000036269	Bone morphogenetic protein 4.	Kruppel-like factor 4 (Gut).	0.478
BMP4	SMAD1	ENSPTRP00000010780	ENSPTRP00000028297	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog.	0.576
BMP4	SOX17	ENSPTRP00000010780	ENSPTRP00000034688	Bone morphogenetic protein 4.	SOX17 isoform 1.	0.523
BMP4	SOX2	ENSPTRP00000010780	ENSPTRP00000046752	Bone morphogenetic protein 4.	SRY-box transcription factor 2.	0.566
BMP4	TBX6	ENSPTRP00000010780	ENSPTRP00000013650	Bone morphogenetic protein 4.	T-box transcription factor 6.	0.476
BMP4	WNT3A	ENSPTRP00000010780	ENSPTRP00000051074	Bone morphogenetic protein 4.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.708
BMP4-2	CTNNB1	ENSPTRP00000080656	ENSPTRP00000044466	Bone morphogenetic protein 4.	Catenin (Cadherin-associated protein), beta 1, 88kDa.	0.551
BMP4-2	EYA1	ENSPTRP00000080656	ENSPTRP00000034805	Bone morphogenetic protein 4.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.411
BMP4-2	GATA6	ENSPTRP00000080656	ENSPTRP00000016858	Bone morphogenetic protein 4.	GATA binding protein 6.	0.546
BMP4-2	KLF4	ENSPTRP00000080656	ENSPTRP00000036269	Bone morphogenetic protein 4.	Kruppel-like factor 4 (Gut).	0.478
BMP4-2	SMAD1	ENSPTRP00000080656	ENSPTRP00000028297	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog.	0.576
BMP4-2	SOX17	ENSPTRP00000080656	ENSPTRP00000034688	Bone morphogenetic protein 4.	SOX17 isoform 1.	0.523
BMP4-2	SOX2	ENSPTRP00000080656	ENSPTRP00000046752	Bone morphogenetic protein 4.	SRY-box transcription factor 2.	0.566
BMP4-2	TBX6	ENSPTRP00000080656	ENSPTRP00000013650	Bone morphogenetic protein 4.	T-box transcription factor 6.	0.476
BMP4-2	WNT3A	ENSPTRP00000080656	ENSPTRP00000051074	Bone morphogenetic protein 4.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.708
CDC73	CTNNB1	ENSPTRP00000090347	ENSPTRP00000044466	Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog.	Catenin (Cadherin-associated protein), beta 1, 88kDa.	0.907
CDC73	CTR9	ENSPTRP00000090347	ENSPTRP00000041382	Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog.	Ctr9, Paf1/RNA polymerase II complex component, homolog.	0.999