18 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PDGFRB	Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
	BVES	Blood vessel epicardial substance. (360 aa)
	EDN1	EDN1 isoform 1. (212 aa)
	EDNRA	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
	PITX2	Homeobox protein. (324 aa)
	FLRT3	Fibronectin leucine rich transmembrane protein 3. (649 aa)
	NDRG4	NDRG family member 4. (226 aa)
	MESP1	Mesoderm posterior bHLH transcription factor 1. (268 aa)
	FOLR1	Folate receptor alpha. (257 aa)
	CDC42	Cell division cycle 42 (GTP binding protein, 25kDa). (191 aa)
	SNAI2	Snail family transcriptional repressor 2. (268 aa)
	DCHS1	DCHS1 isoform 1. (3298 aa)
	TBX5	T-box transcription factor 5. (518 aa)
	S1PR2	Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family. (353 aa)
	HAND2	Heart and neural crest derivatives expressed 2. (217 aa)
	TWIST1	TWIST1 isoform 2. (163 aa)
	NOTCH1	NOTCH1 isoform 1. (2555 aa)
	ENG	ENG isoform 1. (658 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BVES	NDRG4	ENSPTRP00000031520	ENSPTRP00000013967	Blood vessel epicardial substance.	NDRG family member 4.	0.459
CDC42	EDN1	ENSPTRP00000077648	ENSPTRP00000030273	Cell division cycle 42 (GTP binding protein, 25kDa).	EDN1 isoform 1.	0.435
CDC42	PDGFRB	ENSPTRP00000077648	ENSPTRP00000080188	Cell division cycle 42 (GTP binding protein, 25kDa).	Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells.	0.430
EDN1	CDC42	ENSPTRP00000030273	ENSPTRP00000077648	EDN1 isoform 1.	Cell division cycle 42 (GTP binding protein, 25kDa).	0.435
EDN1	EDNRA	ENSPTRP00000030273	ENSPTRP00000028311	EDN1 isoform 1.	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	0.999
EDN1	ENG	ENSPTRP00000030273	ENSPTRP00000036576	EDN1 isoform 1.	ENG isoform 1.	0.562
EDN1	PDGFRB	ENSPTRP00000030273	ENSPTRP00000080188	EDN1 isoform 1.	Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells.	0.414
EDNRA	EDN1	ENSPTRP00000028311	ENSPTRP00000030273	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	EDN1 isoform 1.	0.999
EDNRA	HAND2	ENSPTRP00000028311	ENSPTRP00000050916	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Heart and neural crest derivatives expressed 2.	0.461
EDNRA	PDGFRB	ENSPTRP00000028311	ENSPTRP00000080188	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells.	0.432
EDNRA	PITX2	ENSPTRP00000028311	ENSPTRP00000028118	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Homeobox protein.	0.492
ENG	EDN1	ENSPTRP00000036576	ENSPTRP00000030273	ENG isoform 1.	EDN1 isoform 1.	0.562
ENG	PDGFRB	ENSPTRP00000036576	ENSPTRP00000080188	ENG isoform 1.	Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells.	0.516
FLRT3	PITX2	ENSPTRP00000022750	ENSPTRP00000028118	Fibronectin leucine rich transmembrane protein 3.	Homeobox protein.	0.453
HAND2	EDNRA	ENSPTRP00000050916	ENSPTRP00000028311	Heart and neural crest derivatives expressed 2.	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	0.461
HAND2	MESP1	ENSPTRP00000050916	ENSPTRP00000012723	Heart and neural crest derivatives expressed 2.	Mesoderm posterior bHLH transcription factor 1.	0.565
HAND2	PITX2	ENSPTRP00000050916	ENSPTRP00000028118	Heart and neural crest derivatives expressed 2.	Homeobox protein.	0.471
HAND2	TBX5	ENSPTRP00000050916	ENSPTRP00000069028	Heart and neural crest derivatives expressed 2.	T-box transcription factor 5.	0.782
MESP1	HAND2	ENSPTRP00000012723	ENSPTRP00000050916	Mesoderm posterior bHLH transcription factor 1.	Heart and neural crest derivatives expressed 2.	0.565
MESP1	TBX5	ENSPTRP00000012723	ENSPTRP00000069028	Mesoderm posterior bHLH transcription factor 1.	T-box transcription factor 5.	0.525