STRINGSTRING
BASP1 BASP1 SMO-2 SMO-2 KLF15 KLF15 SALL1 SALL1 HES1 HES1 WNT4 WNT4 NPHS1 NPHS1 FOXC2 FOXC2 GDNF GDNF AMER1 AMER1 GLIS2 GLIS2 NOTCH1 NOTCH1 EXT1 EXT1 SMO SMO MAGI2 MAGI2 GLI3 GLI3 TCF21 TCF21 EDNRA EDNRA PROM1 PROM1 LAMB2 LAMB2 PDGFB PDGFB JAG1 JAG1 SIX2 SIX2 NPHS2 NPHS2 CD34 CD34 EDNRB EDNRB BMP4 BMP4 MYO1E MYO1E IQGAP1 IQGAP1 FOXJ1 FOXJ1 OSR1 OSR1 LOC107968591 LOC107968591 BMP4-2 BMP4-2 CD24 CD24 STAT1 STAT1 MTSS1 MTSS1 PAX8 PAX8 PTCH1 PTCH1 WT1 WT1 MEF2C MEF2C PAX2 PAX2 PTPRO PTPRO GPR4 GPR4 LGR4 LGR4 NOTCH2 NOTCH2 POU3F3 POU3F3 PODXL PODXL ASXL1 ASXL1 ENSPTRP00000069764 ENSPTRP00000069764
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BASP1Brain abundant, membrane attached signal protein 1. (226 aa)
SMO-2Smoothened, frizzled class receptor. (786 aa)
KLF15Kruppel-like factor 15. (416 aa)
SALL1SALL1 isoform 2. (1326 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
NPHS1NPHS1 isoform 1. (1241 aa)
FOXC2Forkhead box C2 (MFH-1, mesenchyme forkhead 1). (501 aa)
GDNFGlial cell derived neurotrophic factor. (228 aa)
AMER1APC membrane recruitment protein 1. (805 aa)
GLIS2GLIS family zinc finger 2. (524 aa)
NOTCH1NOTCH1 isoform 1. (2555 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
SMOSMO isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
MAGI2Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1283 aa)
GLI3Transcriptional repressor GLI3R; Has a dual function as a transcriptional activator and a repressor of the sonic hedgehog (Shh) pathway, and plays a role in limb development. The full-length GLI3 form (GLI3FL) after phosphorylation and nuclear translocation, acts as an activator (GLI3A) while GLI3R, its C-terminally truncated form, acts as a repressor. A proper balance between the GLI3 activator and the repressor GLI3R, rather than the repressor gradient itself or the activator/repressor ratio gradient, specifies limb digit number and identity. In concert with TRPS1, plays a role in re [...] (1580 aa)
TCF21Transcription factor 21. (179 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
PROM1PROM1 isoform 12. (865 aa)
LAMB2Laminin, beta 2 (Laminin S). (1798 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
SIX2SIX homeobox 2. (291 aa)
NPHS2NPHS2 stomatin family member, podocin. (383 aa)
CD34CD34 isoform 1. (328 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (532 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
MYO1EMYO1E isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1108 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1657 aa)
FOXJ1FOXJ1 isoform 1. (421 aa)
OSR1Odd-skipped related transcription factor 1. (266 aa)
LOC107968591CD24 isoform 1. (80 aa)
BMP4-2Bone morphogenetic protein 4. (408 aa)
CD24CD24 isoform 8. (129 aa)
STAT1Signal transducer and activator of transcription. (758 aa)
MTSS1MTSS I-BAR domain containing 1. (759 aa)
PAX8PAX8 isoform 1. (456 aa)
PTCH1PTCH1 isoform 8. (1428 aa)
WT1WT1 transcription factor. (514 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
PAX2PAX2 isoform 1. (417 aa)
PTPROProtein tyrosine phosphatase receptor type O. (1216 aa)
GPR4G protein-coupled receptor 4; Belongs to the G-protein coupled receptor 1 family. (362 aa)
LGR4LGR4 isoform 2. (951 aa)
NOTCH2NOTCH2 isoform 1. (2612 aa)
POU3F3POU domain protein. (476 aa)
PODXLPodocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family. (556 aa)
ASXL1ASXL transcriptional regulator 1. (1548 aa)
ENSPTRP00000069764annotation not available (1213 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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