13 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	WNT11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
	BCCIP	BRCA2 and CDKN1A interacting protein. (322 aa)
	BMP2	Bone morphogenetic protein 2. (398 aa)
	JAG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
	NKX2-2	NKX2-2 isoform 1. (273 aa)
	OTP	Orthopedia homeobox. (325 aa)
	NOTCH1	NOTCH1 isoform 1. (2555 aa)
	GATA2	GATA binding protein 2. (480 aa)
	WNT4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
	LHX3	LHX3 isoform 2. (402 aa)
	HES1	Hes family bHLH transcription factor 1. (280 aa)
	FGF8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
	ASCL1	Achaete-scute family bHLH transcription factor 1. (232 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASCL1	GATA2	ENSPTRP00000077846	ENSPTRP00000054198	Achaete-scute family bHLH transcription factor 1.	GATA binding protein 2.	0.436
ASCL1	HES1	ENSPTRP00000077846	ENSPTRP00000064171	Achaete-scute family bHLH transcription factor 1.	Hes family bHLH transcription factor 1.	0.522
ASCL1	LHX3	ENSPTRP00000077846	ENSPTRP00000063429	Achaete-scute family bHLH transcription factor 1.	LHX3 isoform 2.	0.400
ASCL1	NKX2-2	ENSPTRP00000077846	ENSPTRP00000022825	Achaete-scute family bHLH transcription factor 1.	NKX2-2 isoform 1.	0.685
BMP2	FGF8	ENSPTRP00000022701	ENSPTRP00000075677	Bone morphogenetic protein 2.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.662
BMP2	WNT4	ENSPTRP00000022701	ENSPTRP00000063328	Bone morphogenetic protein 2.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.426
FGF8	BMP2	ENSPTRP00000075677	ENSPTRP00000022701	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Bone morphogenetic protein 2.	0.662
GATA2	ASCL1	ENSPTRP00000054198	ENSPTRP00000077846	GATA binding protein 2.	Achaete-scute family bHLH transcription factor 1.	0.436
GATA2	LHX3	ENSPTRP00000054198	ENSPTRP00000063429	GATA binding protein 2.	LHX3 isoform 2.	0.485
HES1	ASCL1	ENSPTRP00000064171	ENSPTRP00000077846	Hes family bHLH transcription factor 1.	Achaete-scute family bHLH transcription factor 1.	0.522
HES1	JAG1	ENSPTRP00000064171	ENSPTRP00000022729	Hes family bHLH transcription factor 1.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.532
HES1	NOTCH1	ENSPTRP00000064171	ENSPTRP00000036924	Hes family bHLH transcription factor 1.	NOTCH1 isoform 1.	0.642
JAG1	HES1	ENSPTRP00000022729	ENSPTRP00000064171	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Hes family bHLH transcription factor 1.	0.532
JAG1	NOTCH1	ENSPTRP00000022729	ENSPTRP00000036924	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	NOTCH1 isoform 1.	0.999
LHX3	ASCL1	ENSPTRP00000063429	ENSPTRP00000077846	LHX3 isoform 2.	Achaete-scute family bHLH transcription factor 1.	0.400
LHX3	GATA2	ENSPTRP00000063429	ENSPTRP00000054198	LHX3 isoform 2.	GATA binding protein 2.	0.485
NKX2-2	ASCL1	ENSPTRP00000022825	ENSPTRP00000077846	NKX2-2 isoform 1.	Achaete-scute family bHLH transcription factor 1.	0.685
NOTCH1	HES1	ENSPTRP00000036924	ENSPTRP00000064171	NOTCH1 isoform 1.	Hes family bHLH transcription factor 1.	0.642
NOTCH1	JAG1	ENSPTRP00000036924	ENSPTRP00000022729	NOTCH1 isoform 1.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.999
WNT11	WNT4	ENSPTRP00000007028	ENSPTRP00000063328	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.544