9 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	JAG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
	CDC42	Cell division cycle 42 (GTP binding protein, 25kDa). (191 aa)
	HES1	Hes family bHLH transcription factor 1. (280 aa)
	HAND2	Heart and neural crest derivatives expressed 2. (217 aa)
	TWIST1	TWIST1 isoform 2. (163 aa)
	EDN1	EDN1 isoform 1. (212 aa)
	EDNRA	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
	PITX2	Homeobox protein. (324 aa)
	FOLR1	Folate receptor alpha. (257 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	EDN1	ENSPTRP00000077648	ENSPTRP00000030273	Cell division cycle 42 (GTP binding protein, 25kDa).	EDN1 isoform 1.	0.435
EDN1	CDC42	ENSPTRP00000030273	ENSPTRP00000077648	EDN1 isoform 1.	Cell division cycle 42 (GTP binding protein, 25kDa).	0.435
EDN1	EDNRA	ENSPTRP00000030273	ENSPTRP00000028311	EDN1 isoform 1.	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	0.999
EDNRA	EDN1	ENSPTRP00000028311	ENSPTRP00000030273	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	EDN1 isoform 1.	0.999
EDNRA	HAND2	ENSPTRP00000028311	ENSPTRP00000050916	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Heart and neural crest derivatives expressed 2.	0.461
EDNRA	PITX2	ENSPTRP00000028311	ENSPTRP00000028118	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Homeobox protein.	0.492
HAND2	EDNRA	ENSPTRP00000050916	ENSPTRP00000028311	Heart and neural crest derivatives expressed 2.	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	0.461
HAND2	PITX2	ENSPTRP00000050916	ENSPTRP00000028118	Heart and neural crest derivatives expressed 2.	Homeobox protein.	0.471
HES1	JAG1	ENSPTRP00000064171	ENSPTRP00000022729	Hes family bHLH transcription factor 1.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.532
JAG1	HES1	ENSPTRP00000022729	ENSPTRP00000064171	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Hes family bHLH transcription factor 1.	0.532
JAG1	TWIST1	ENSPTRP00000022729	ENSPTRP00000048124	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	TWIST1 isoform 2.	0.549
PITX2	EDNRA	ENSPTRP00000028118	ENSPTRP00000028311	Homeobox protein.	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	0.492
PITX2	HAND2	ENSPTRP00000028118	ENSPTRP00000050916	Homeobox protein.	Heart and neural crest derivatives expressed 2.	0.471
TWIST1	JAG1	ENSPTRP00000048124	ENSPTRP00000022729	TWIST1 isoform 2.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.549