STRINGSTRING
WNT5A WNT5A WNT8A WNT8A BMP4-2 BMP4-2 HEYL HEYL BMPR1A BMPR1A BMP4 BMP4 NOG NOG MKS1 MKS1 TGFB1 TGFB1 BMP2 BMP2 JAG1 JAG1 HEY2 HEY2 SNAI2 SNAI2 NOTCH1 NOTCH1 CTNNB1 CTNNB1 WNT3A WNT3A MSX1 MSX1 ENSPTRP00000064416 ENSPTRP00000064416 SNAI1 SNAI1 GALNT11 GALNT11 HEY1 HEY1 DLL4 DLL4 ACVR1 ACVR1 NOTCH2 NOTCH2 GALNT11-2 GALNT11-2 RBPJ RBPJ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (369 aa)
BMP4-2Bone morphogenetic protein 4. (408 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
MKS1MKS transition zone complex subunit 1. (559 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
BMP2Bone morphogenetic protein 2. (398 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif 2. (337 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
NOTCH1NOTCH1 isoform 1. (2555 aa)
CTNNB1Catenin (Cadherin-associated protein), beta 1, 88kDa. (781 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
MSX1Homeobox protein MSX-1; Acts as a transcriptional repressor. May play a role in limb- pattern formation. Acts in cranofacial development and specifically in odontogenesis (By similarity). (303 aa)
ENSPTRP00000064416annotation not available (502 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
GALNT11Polypeptide N-acetylgalactosaminyltransferase. (608 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (696 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
NOTCH2NOTCH2 isoform 1. (2612 aa)
GALNT11-2Polypeptide N-acetylgalactosaminyltransferase 11. (608 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (500 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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