8 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BMP4-2	Bone morphogenetic protein 4. (408 aa)
	ACVR1	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
	ENSPTRP00000064416	annotation not available (502 aa)
	MSX1	Homeobox protein MSX-1; Acts as a transcriptional repressor. May play a role in limb- pattern formation. Acts in cranofacial development and specifically in odontogenesis (By similarity). (303 aa)
	BMP2	Bone morphogenetic protein 2. (398 aa)
	BMPR1A	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	NOG	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACVR1	BMP2	ENSPTRP00000075770	ENSPTRP00000022701	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 2.	0.985
ACVR1	BMP4	ENSPTRP00000075770	ENSPTRP00000010780	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 4.	0.984
ACVR1	BMP4-2	ENSPTRP00000075770	ENSPTRP00000080656	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 4.	0.855
ACVR1	BMPR1A	ENSPTRP00000075770	ENSPTRP00000004727	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.983
ACVR1	ENSPTRP00000064416	ENSPTRP00000075770	ENSPTRP00000064416	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	annotation not available	0.840
ACVR1	NOG	ENSPTRP00000075770	ENSPTRP00000016018	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.663
BMP2	ACVR1	ENSPTRP00000022701	ENSPTRP00000075770	Bone morphogenetic protein 2.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.985
BMP2	BMP4	ENSPTRP00000022701	ENSPTRP00000010780	Bone morphogenetic protein 2.	Bone morphogenetic protein 4.	0.951
BMP2	BMP4-2	ENSPTRP00000022701	ENSPTRP00000080656	Bone morphogenetic protein 2.	Bone morphogenetic protein 4.	0.530
BMP2	BMPR1A	ENSPTRP00000022701	ENSPTRP00000004727	Bone morphogenetic protein 2.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.996
BMP2	ENSPTRP00000064416	ENSPTRP00000022701	ENSPTRP00000064416	Bone morphogenetic protein 2.	annotation not available	0.964
BMP2	MSX1	ENSPTRP00000022701	ENSPTRP00000055966	Bone morphogenetic protein 2.	Homeobox protein MSX-1; Acts as a transcriptional repressor. May play a role in limb- pattern formation. Acts in cranofacial development and specifically in odontogenesis (By similarity).	0.572
BMP2	NOG	ENSPTRP00000022701	ENSPTRP00000016018	Bone morphogenetic protein 2.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.998
BMP4	ACVR1	ENSPTRP00000010780	ENSPTRP00000075770	Bone morphogenetic protein 4.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.984
BMP4	BMP2	ENSPTRP00000010780	ENSPTRP00000022701	Bone morphogenetic protein 4.	Bone morphogenetic protein 2.	0.951
BMP4	BMPR1A	ENSPTRP00000010780	ENSPTRP00000004727	Bone morphogenetic protein 4.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.988
BMP4	ENSPTRP00000064416	ENSPTRP00000010780	ENSPTRP00000064416	Bone morphogenetic protein 4.	annotation not available	0.846
BMP4	MSX1	ENSPTRP00000010780	ENSPTRP00000055966	Bone morphogenetic protein 4.	Homeobox protein MSX-1; Acts as a transcriptional repressor. May play a role in limb- pattern formation. Acts in cranofacial development and specifically in odontogenesis (By similarity).	0.682
BMP4	NOG	ENSPTRP00000010780	ENSPTRP00000016018	Bone morphogenetic protein 4.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.998
BMP4-2	ACVR1	ENSPTRP00000080656	ENSPTRP00000075770	Bone morphogenetic protein 4.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.855