STRINGSTRING
HEY1 HEY1 CK820_G0042363 CK820_G0042363 RFLNA RFLNA ENPP1 ENPP1 BCOR BCOR NOTCH1 NOTCH1 ASPN ASPN PTK2B PTK2B NOS3 NOS3 HEY2 HEY2 STATH STATH AHSG AHSG TRPM4 TRPM4 TGFB1 TGFB1 SOX9 SOX9 RFLNB RFLNB HIF1A HIF1A FGF23 FGF23 LTBP3 LTBP3 PTH PTH SRGN SRGN ECM1 ECM1 GATA1 GATA1 LOC745935 LOC745935 BCOR-2 BCOR-2 CCR1 CCR1 ROCK2 ROCK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
CK820_G0042363TRPM4 isoform 1. (1251 aa)
RFLNARFLNA isoform 1. (216 aa)
ENPP1ENPP1 isoform 1. (925 aa)
BCORBCL6 corepressor. (1755 aa)
NOTCH1NOTCH1 isoform 1. (2555 aa)
ASPNAsporin. (378 aa)
PTK2BPTK2B protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1203 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif 2. (337 aa)
STATHSTATH isoform 1. (62 aa)
AHSGAlpha-2-HS-glycoprotein chain A; Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions (By similarity); Belongs to the fetuin family. (368 aa)
TRPM4Transient receptor potential cation channel, subfamily M, member 4. (1306 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
SOX9Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa)
RFLNBRFLNB isoform 1. (144 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1297 aa)
PTHParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa)
SRGNSRGN isoform 1. (162 aa)
ECM1Extracellular matrix protein 1. (540 aa)
GATA1GATA binding protein 1. (413 aa)
LOC745935C-C motif chemokine. (87 aa)
BCOR-2BCL6 corepressor. (1755 aa)
CCR1C-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (355 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (18%) [HD]