(26 nodes) Negative regulation of T cell apoptotic process network (Pan troglodytes)

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Your Input:
	KIFAP3	Kinesin-associated protein 3. (792 aa)
	GPAM	Glycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa)
	FADD	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	HIF1A	Hypoxia inducible factor 1 subunit alpha. (850 aa)
	ARG2	Arginase. (354 aa)
	PIP	Prolactin-inducible protein homolog; Belongs to the PIP family. (146 aa)
	IDO1	IDO1 isoform 2. (403 aa)
	DOCK8	DOCK8 isoform 2; Belongs to the DOCK family. (2057 aa)
	SLC46A2	Solute carrier family 46 member 2. (475 aa)
	TSC22D3	TSC22 domain family, member 3. (200 aa)
	JAK3	Tyrosine-protein kinase. (1124 aa)
	BCL3	BCL3 transcription coactivator. (454 aa)
	CD27	CD27 isoform 1. (260 aa)
	BCL11B	BAF chromatin remodeling complex subunit BCL11B. (894 aa)
	RAG1	V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (955 aa)
	ST3GAL1	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1; Responsible for the synthesis of the sequence NeuAc-alpha- 2,3-Gal-beta-1,3-GalNAc- found on sugar chains O-linked to Thr or Ser and also as a terminal sequence on certain gangliosides. SIAT4A and SIAT4B sialylate the same acceptor substrates but exhibit different Km values. (340 aa)
	ADA	Adenosine deaminase. (412 aa)
	IL7R	Interleukin 7 receptor. (459 aa)
	PRKCQ	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (845 aa)
	BMP4-2	Bone morphogenetic protein 4. (408 aa)
	RORC	RAR related orphan receptor C. (525 aa)
	CCL5	C-C motif chemokine. (91 aa)
	PTCRA	Pre T cell antigen receptor alpha. (295 aa)
	BCL2	BCL2 apoptosis regulator. (239 aa)
	EFNA1	EFNA1 isoform 2; Belongs to the ephrin family. (205 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADA	RAG1	ENSPTRP00000073897	ENSPTRP00000064414	Adenosine deaminase.	V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...]	0.470
ARG2	HIF1A	ENSPTRP00000010966	ENSPTRP00000010887	Arginase.	Hypoxia inducible factor 1 subunit alpha.	0.409
ARG2	IDO1	ENSPTRP00000010966	ENSPTRP00000034569	Arginase.	IDO1 isoform 2.	0.610
BCL2	BCL3	ENSPTRP00000090293	ENSPTRP00000048640	BCL2 apoptosis regulator.	BCL3 transcription coactivator.	0.493
BCL2	CD27	ENSPTRP00000090293	ENSPTRP00000050524	BCL2 apoptosis regulator.	CD27 isoform 1.	0.402
BCL2	FADD	ENSPTRP00000090293	ENSPTRP00000006883	BCL2 apoptosis regulator.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.609
BCL2	HIF1A	ENSPTRP00000090293	ENSPTRP00000010887	BCL2 apoptosis regulator.	Hypoxia inducible factor 1 subunit alpha.	0.803
BCL2	IL7R	ENSPTRP00000090293	ENSPTRP00000075860	BCL2 apoptosis regulator.	Interleukin 7 receptor.	0.582
BCL3	BCL2	ENSPTRP00000048640	ENSPTRP00000090293	BCL3 transcription coactivator.	BCL2 apoptosis regulator.	0.493
CCL5	CD27	ENSPTRP00000083031	ENSPTRP00000050524	C-C motif chemokine.	CD27 isoform 1.	0.407
CCL5	IDO1	ENSPTRP00000083031	ENSPTRP00000034569	C-C motif chemokine.	IDO1 isoform 2.	0.493
CCL5	IL7R	ENSPTRP00000083031	ENSPTRP00000075860	C-C motif chemokine.	Interleukin 7 receptor.	0.443
CD27	BCL2	ENSPTRP00000050524	ENSPTRP00000090293	CD27 isoform 1.	BCL2 apoptosis regulator.	0.402
CD27	CCL5	ENSPTRP00000050524	ENSPTRP00000083031	CD27 isoform 1.	C-C motif chemokine.	0.407
CD27	IDO1	ENSPTRP00000050524	ENSPTRP00000034569	CD27 isoform 1.	IDO1 isoform 2.	0.457
CD27	IL7R	ENSPTRP00000050524	ENSPTRP00000075860	CD27 isoform 1.	Interleukin 7 receptor.	0.692
FADD	BCL2	ENSPTRP00000006883	ENSPTRP00000090293	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	BCL2 apoptosis regulator.	0.609
HIF1A	ARG2	ENSPTRP00000010887	ENSPTRP00000010966	Hypoxia inducible factor 1 subunit alpha.	Arginase.	0.409
HIF1A	BCL2	ENSPTRP00000010887	ENSPTRP00000090293	Hypoxia inducible factor 1 subunit alpha.	BCL2 apoptosis regulator.	0.803
IDO1	ARG2	ENSPTRP00000034569	ENSPTRP00000010966	IDO1 isoform 2.	Arginase.	0.610