STRINGSTRING
JAK3 JAK3 KIFAP3 KIFAP3 BCL11B BCL11B RAG1 RAG1 ADA ADA BMP4-2 BMP4-2 RORC RORC PTCRA PTCRA EFNA1 EFNA1 HIF1A HIF1A BMP4 BMP4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
JAK3Tyrosine-protein kinase. (1124 aa)
KIFAP3Kinesin-associated protein 3. (792 aa)
BCL11BBAF chromatin remodeling complex subunit BCL11B. (894 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (955 aa)
ADAAdenosine deaminase. (412 aa)
BMP4-2Bone morphogenetic protein 4. (408 aa)
RORCRAR related orphan receptor C. (525 aa)
PTCRAPre T cell antigen receptor alpha. (295 aa)
EFNA1EFNA1 isoform 2; Belongs to the ephrin family. (205 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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