17 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SMO-2	Smoothened, frizzled class receptor. (786 aa)
	IFT172	Intraflagellar transport 172 homolog. (1767 aa)
	HSPB11	Heat shock protein family B (small) member 11. (214 aa)
	NOTCH2	NOTCH2 isoform 1. (2612 aa)
	CITED2	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
	PITX2	Homeobox protein. (324 aa)
	DLL1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
	MNS1	Meiosis-specific nuclear structural protein 1. (495 aa)
	ARL13B	ADP ribosylation factor like GTPase 13B. (428 aa)
	SMO	SMO isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
	NOTCH1	NOTCH1 isoform 1. (2555 aa)
	SETDB2	SET domain bifurcated histone lysine methyltransferase 2. (719 aa)
	AHI1	Abelson helper integration site 1. (1196 aa)
	EPB41L5	Erythrocyte membrane protein band 4.1 like 5. (733 aa)
	PKD1L1	PKD1L1 isoform 1. (2857 aa)
	ZIC3	Zic family member 3. (466 aa)
	PKD1L1-2	Polycystin 1 like 1, transient receptor potential channel interacting. (2857 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHI1	ARL13B	ENSPTRP00000031804	ENSPTRP00000026120	Abelson helper integration site 1.	ADP ribosylation factor like GTPase 13B.	0.674
ARL13B	AHI1	ENSPTRP00000026120	ENSPTRP00000031804	ADP ribosylation factor like GTPase 13B.	Abelson helper integration site 1.	0.674
ARL13B	IFT172	ENSPTRP00000026120	ENSPTRP00000071079	ADP ribosylation factor like GTPase 13B.	Intraflagellar transport 172 homolog.	0.461
ARL13B	SMO	ENSPTRP00000026120	ENSPTRP00000033707	ADP ribosylation factor like GTPase 13B.	SMO isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family.	0.467
ARL13B	SMO-2	ENSPTRP00000026120	ENSPTRP00000067533	ADP ribosylation factor like GTPase 13B.	Smoothened, frizzled class receptor.	0.467
DLL1	NOTCH1	ENSPTRP00000032142	ENSPTRP00000036924	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	NOTCH1 isoform 1.	0.998
DLL1	NOTCH2	ENSPTRP00000032142	ENSPTRP00000075807	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	NOTCH2 isoform 1.	0.994
HSPB11	IFT172	ENSPTRP00000074844	ENSPTRP00000071079	Heat shock protein family B (small) member 11.	Intraflagellar transport 172 homolog.	0.986
IFT172	ARL13B	ENSPTRP00000071079	ENSPTRP00000026120	Intraflagellar transport 172 homolog.	ADP ribosylation factor like GTPase 13B.	0.461
IFT172	HSPB11	ENSPTRP00000071079	ENSPTRP00000074844	Intraflagellar transport 172 homolog.	Heat shock protein family B (small) member 11.	0.986
IFT172	SMO	ENSPTRP00000071079	ENSPTRP00000033707	Intraflagellar transport 172 homolog.	SMO isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family.	0.408
IFT172	SMO-2	ENSPTRP00000071079	ENSPTRP00000067533	Intraflagellar transport 172 homolog.	Smoothened, frizzled class receptor.	0.408
NOTCH1	DLL1	ENSPTRP00000036924	ENSPTRP00000032142	NOTCH1 isoform 1.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.998
NOTCH1	NOTCH2	ENSPTRP00000036924	ENSPTRP00000075807	NOTCH1 isoform 1.	NOTCH2 isoform 1.	0.945
NOTCH2	DLL1	ENSPTRP00000075807	ENSPTRP00000032142	NOTCH2 isoform 1.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.994
NOTCH2	NOTCH1	ENSPTRP00000075807	ENSPTRP00000036924	NOTCH2 isoform 1.	NOTCH1 isoform 1.	0.945
PITX2	ZIC3	ENSPTRP00000028118	ENSPTRP00000066439	Homeobox protein.	Zic family member 3.	0.533
SMO	ARL13B	ENSPTRP00000033707	ENSPTRP00000026120	SMO isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family.	ADP ribosylation factor like GTPase 13B.	0.467
SMO	IFT172	ENSPTRP00000033707	ENSPTRP00000071079	SMO isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family.	Intraflagellar transport 172 homolog.	0.408
SMO-2	ARL13B	ENSPTRP00000067533	ENSPTRP00000026120	Smoothened, frizzled class receptor.	ADP ribosylation factor like GTPase 13B.	0.467