94 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PRKAA1	Non-specific serine/threonine protein kinase. (574 aa)
	SYT1	Synaptotagmin 1. (422 aa)
	CLIC4	Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (253 aa)
	HPCA	HPCA isoform 3. (193 aa)
	HSPA5	Heat shock 70kDa protein 5 (Glucose-regulated protein, 78kDa); Belongs to the heat shock protein 70 family. (654 aa)
	PRKAA2	Non-specific serine/threonine protein kinase. (552 aa)
	SLC25A24	Solute carrier family 25 (Mitochondrial carrier phosphate carrier), member 24; Belongs to the mitochondrial carrier (TC 2.A.29) family. (477 aa)
	MCOLN1	MCOLN1 isoform 1. (601 aa)
	ITPKC	Kinase; Belongs to the inositol phosphokinase (IPK) family. (683 aa)
	SYT3	Synaptotagmin 3. (590 aa)
	SYT5	Synaptotagmin 5. (386 aa)
	HPCAL1	Hippocalcin-like protein 1. (193 aa)
	KCNB1	Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa)
	CPNE9	Copine family member 9. (553 aa)
	ADD1	ADD1 isoform 5. (768 aa)
	PKD2	Polycystin 2, transient receptor potential cation channel. (968 aa)
	CRHBP	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)
	ADGRV1	ADGRV1 isoform 1; Belongs to the G-protein coupled receptor 2 family. (6306 aa)
	EDN1	EDN1 isoform 1. (212 aa)
	GPLD1	GPLD1 isoform 2. (840 aa)
	CPNE5	CPNE5 isoform 2. (593 aa)
	GUCA1A	GUCA1A isoform 1. (207 aa)
	ADCY1	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1119 aa)
	CPNE3	CPNE3 isoform 1. (537 aa)
	DMTN	Dematin actin binding protein. (405 aa)
	CPNE4	CPNE4 isoform 3. (575 aa)
	ITPKA	Kinase; Belongs to the inositol phosphokinase (IPK) family. (461 aa)
	IQGAP1	IQ motif containing GTPase activating protein 1. (1657 aa)
	CHP2	Calcineurin like EF-hand protein 2. (196 aa)
	LGMN	LGMN isoform 1. (433 aa)
	CPNE6	CPNE6 isoform 2. (565 aa)
	ALOX5AP	Arachidonate 5-lipoxygenase activating protein. (218 aa)
	RASAL1	RAS protein activator like 1. (806 aa)
	CPNE8	CPNE8 isoform 2. (564 aa)
	SYT12	Synaptotagmin 12. (420 aa)
	RASGRP2	RAS guanyl releasing protein 2. (609 aa)
	SYT13	SYT13 isoform 1. (426 aa)
	JUNB	JunB proto-oncogene, AP-1 transcription factor subunit. (347 aa)
	SYT10	Synaptotagmin 10. (523 aa)
	ASPH	ASPH isoform 1. (762 aa)
	SLC25A23	Solute carrier family 25 (Mitochondrial carrier phosphate carrier), member 23; Belongs to the mitochondrial carrier (TC 2.A.29) family. (468 aa)
	ACER1	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (264 aa)
	SYT4	Synaptotagmin 4. (425 aa)
	ALOX15	Arachidonate 15-lipoxygenase. (662 aa)
	DPEP1	Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (392 aa)
	LOC453361	CAPN3 isoform 4; Belongs to the peptidase C2 family. (821 aa)
	NLGN1	NLGN1 isoform 1. (823 aa)
	SYT11	Synaptotagmin 11. (431 aa)
	ADCY1-2	Adenylate cyclase 1. (1119 aa)
	TRPM2	TRPM2 isoform 4. (1393 aa)
	SCN5A	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2016 aa)
	SYT15	SYT15 isoform 1. (479 aa)
	MEF2A	Myocyte enhancer factor 2A. (507 aa)
	SYT7	Synaptotagmin 7. (686 aa)
	NRXN1	NRXN1 isoform 9. (1547 aa)
	ENSPTRP00000073361	annotation not available (388 aa)
	SYT8	Synaptotagmin 8. (401 aa)
	RASA4	Ras-GAP domain-containing protein. (757 aa)
	CPNE7	CPNE7 isoform 2. (526 aa)
	ENSPTRP00000076491	annotation not available (91 aa)
	PLCG2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
	CK820_G0051619	CPNE7 isoform 9. (170 aa)
	ECT2	Epithelial cell transforming sequence 2 oncogene. (958 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
	JUND	JUND isoform 1. (346 aa)
	FOS	Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
	AKR1C3	Aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II). (323 aa)
	BRAF	BRAF isoform 1; Belongs to the protein kinase superfamily. (767 aa)
	ENSPTRP00000081042	annotation not available (262 aa)
	CARF	Amyotrophic lateral sclerosis 2 (Juvenile) chromosome region, candidate 8. (725 aa)
	LOC751039	Uncharacterized protein. (613 aa)
	ENSPTRP00000082912	annotation not available (153 aa)
	FOSB	FosB proto-oncogene, AP-1 transcription factor subunit. (338 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
	CPNE2	CPNE2 isoform 1. (548 aa)
	SYT6	Synaptotagmin 6. (548 aa)
	CAMK2D	Calcium/calmodulin dependent protein kinase II delta. (446 aa)
	BRAF-2	BRAF isoform 2. (766 aa)
	SYT9	Synaptotagmin IX. (491 aa)
	SMPD1	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (504 aa)
	PPIF	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (207 aa)
	ITPKB	Kinase; Belongs to the inositol phosphokinase (IPK) family. (946 aa)
	SYT2	Synaptotagmin 2. (419 aa)
	ENSPTRP00000090382	annotation not available (493 aa)
	EEF2K	Eukaryotic elongation factor 2 kinase. (725 aa)
	NEUROD2	Neurogenic differentiation factor. (382 aa)
	MEF2C	Myocyte enhancer factor 2C. (483 aa)
	CK820_G0030361	RYR1 isoform 5. (4901 aa)
	INHBB	Inhibin subunit beta B. (407 aa)
	RYR3	Ryanodine receptor 3. (4873 aa)
	SYT17	Synaptotagmin 17. (481 aa)
	RYR1	RYR1 isoform 3. (5037 aa)
	NCSTN	NCSTN isoform 1. (721 aa)
	ENDOG	Endonuclease. (297 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACER1	SMPD1	ENSPTRP00000017621	ENSPTRP00000005756	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.	0.932
ADCY1	ADCY8	ENSPTRP00000032741	ENSPTRP00000077396	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.944
ADCY1-2	ADCY8	ENSPTRP00000065256	ENSPTRP00000077396	Adenylate cyclase 1.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.467
ADCY8	ADCY1	ENSPTRP00000077396	ENSPTRP00000032741	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.944
ADCY8	ADCY1-2	ENSPTRP00000077396	ENSPTRP00000065256	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 1.	0.467
ADCY8	CAMK2D	ENSPTRP00000077396	ENSPTRP00000088560	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calcium/calmodulin dependent protein kinase II delta.	0.411
ADD1	DMTN	ENSPTRP00000027304	ENSPTRP00000040561	ADD1 isoform 5.	Dematin actin binding protein.	0.895
ALOX15	ALOX5AP	ENSPTRP00000014679	ENSPTRP00000009797	Arachidonate 15-lipoxygenase.	Arachidonate 5-lipoxygenase activating protein.	0.585
ALOX5AP	ALOX15	ENSPTRP00000009797	ENSPTRP00000014679	Arachidonate 5-lipoxygenase activating protein.	Arachidonate 15-lipoxygenase.	0.585
ASPH	CK820_G0030361	ENSPTRP00000053155	ENSPTRP00000090805	ASPH isoform 1.	RYR1 isoform 5.	0.670
ASPH	EEF2K	ENSPTRP00000053155	ENSPTRP00000089441	ASPH isoform 1.	Eukaryotic elongation factor 2 kinase.	0.429
ASPH	RYR1	ENSPTRP00000053155	ENSPTRP00000092559	ASPH isoform 1.	RYR1 isoform 3.	0.931
ASPH	RYR3	ENSPTRP00000053155	ENSPTRP00000090974	ASPH isoform 1.	Ryanodine receptor 3.	0.911
BRAF	HSPA5	ENSPTRP00000079485	ENSPTRP00000000984	BRAF isoform 1; Belongs to the protein kinase superfamily.	Heat shock 70kDa protein 5 (Glucose-regulated protein, 78kDa); Belongs to the heat shock protein 70 family.	0.488
BRAF	IQGAP1	ENSPTRP00000079485	ENSPTRP00000012743	BRAF isoform 1; Belongs to the protein kinase superfamily.	IQ motif containing GTPase activating protein 1.	0.830
BRAF-2	HSPA5	ENSPTRP00000089230	ENSPTRP00000000984	BRAF isoform 2.	Heat shock 70kDa protein 5 (Glucose-regulated protein, 78kDa); Belongs to the heat shock protein 70 family.	0.488
BRAF-2	IQGAP1	ENSPTRP00000089230	ENSPTRP00000012743	BRAF isoform 2.	IQ motif containing GTPase activating protein 1.	0.830
CAMK2D	ADCY8	ENSPTRP00000088560	ENSPTRP00000077396	Calcium/calmodulin dependent protein kinase II delta.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.411
CAMK2D	HPCA	ENSPTRP00000088560	ENSPTRP00000000863	Calcium/calmodulin dependent protein kinase II delta.	HPCA isoform 3.	0.438
CAMK2D	HPCAL1	ENSPTRP00000088560	ENSPTRP00000020029	Calcium/calmodulin dependent protein kinase II delta.	Hippocalcin-like protein 1.	0.438