STRINGSTRING
ERRFI1 ERRFI1 SLC25A33 SLC25A33 WDTC1 WDTC1 PCSK9 PCSK9 JAK1 JAK1 RPE65 RPE65 HMGCS2 HMGCS2 ENSPTRP00000002048 ENSPTRP00000002048 RAB13 RAB13 USF1 USF1 DDR2 DDR2 SLC30A10 SLC30A10 PARP1 PARP1 ANKRD30A ANKRD30A EIF4EBP2 EIF4EBP2 GOT1 GOT1 PIK3C2A PIK3C2A CSRP3 CSRP3 MEN1 MEN1 UCP2 UCP2 IL18 IL18 WNT1 WNT1 SP1 SP1 STAT6 STAT6 SOCS2 SOCS2 PLA2G1B PLA2G1B KL KL FOXO1 FOXO1 RB1 RB1 TBC1D4 TBC1D4 IRS2 IRS2 PCK2 PCK2 SRSF5 SRSF5 CK820_G0057069 CK820_G0057069 CYFIP1 CYFIP1 CSK CSK IGF1R IGF1R ENSPTRP00000013791 ENSPTRP00000013791 APRT APRT SLC2A4 SLC2A4 NDEL1 NDEL1 GLP2R GLP2R CDC6 CDC6 STAT5A STAT5A HDAC5 HDAC5 PDK2 PDK2 RPS6KB1 RPS6KB1 BRIP1 BRIP1 GH1 GH1 GRB2 GRB2 LPIN2 LPIN2 RAB12 RAB12 RAB8A RAB8A PIK3R2 PIK3R2 TGFB1 TGFB1 GSK3A GSK3A CEACAM1 CEACAM1 FGF21 FGF21 CYP1B1 CYP1B1 LHCGR LHCGR INSIG2 INSIG2 LOC735535 LOC735535 GRB14 GRB14 IRS1 IRS1 CAPN10 CAPN10 TRIB3 TRIB3 PLCB1 PLCB1 PCK1 PCK1 UMODL1 UMODL1 KAT2B KAT2B SMARCC1 SMARCC1 SLC26A6 SLC26A6 PRKCD PRKCD APPL1 APPL1 GHSR GHSR ADIPOQ ADIPOQ OTOP1 OTOP1 GNRHR GNRHR NKX6-1 NKX6-1 NFKB1 NFKB1 CCNA2 CCNA2 GAB1 GAB1 POU4F2 POU4F2 EDNRA EDNRA SRD5A1 SRD5A1 MAP1B MAP1B CRHBP CRHBP FER FER APC APC AP3S1 AP3S1 SPINK1 SPINK1 EDN1 EDN1 GPLD1 GPLD1 GLP1R GLP1R GCLC GCLC PHIP PHIP ARG1 ARG1 MAS1 MAS1 HDAC9 HDAC9 IGFBP1 IGFBP1 POR-2 POR-2 YWHAG YWHAG PDK4 PDK4 CAV1 CAV1 RARRES2 RARRES2 INSIG1 INSIG1 PLAT PLAT CYP11B1 CYP11B1 DNAI1 DNAI1 FBP1 FBP1 RABGAP1 RABGAP1 SLC2A8 SLC2A8 ASS1 ASS1 SYAP1 SYAP1 CPEB2 CPEB2 INPP5K INPP5K GPT GPT NR4A1 NR4A1 CDK4 CDK4 SLC29A2 SLC29A2 JAK3 JAK3 NCOA5 NCOA5 FN1 FN1 POTEA POTEA GCK GCK PTPN1 PTPN1 PRKDC PRKDC LYN LYN GPR173 GPR173 SLC22A12 SLC22A12 SLC27A1 SLC27A1 TYK2 TYK2 ENPP1 ENPP1 PNPLA3 PNPLA3 IDE IDE SHC1 SHC1 RAB15 RAB15 STXBP4 STXBP4 FOXC2 FOXC2 RAP1GDS1 RAP1GDS1 GH1-2 GH1-2 RELA RELA PKLR PKLR PTPRA PTPRA TRARG1 TRARG1 GCGR GCGR GRB10 GRB10 FOXO4 FOXO4 CAV2 CAV2 SELENOS SELENOS PDE3B PDE3B ZFP36L1 ZFP36L1 ENSPTRP00000061612 ENSPTRP00000061612 ENSPTRP00000062007 ENSPTRP00000062007 ENSPTRP00000062039 ENSPTRP00000062039 INSR INSR AGTR1 AGTR1 LOC104002294 LOC104002294 GHRHR GHRHR PIK3R3 PIK3R3 SLC39A14 SLC39A14 ENSPTRP00000064446 ENSPTRP00000064446 NFE2L2 NFE2L2 BAIAP2 BAIAP2 CK820_G0011608 CK820_G0011608 XBP1 XBP1 AHCYL1 AHCYL1 PRKCI PRKCI SLC9A1 SLC9A1 FBN1 FBN1 POR-3 POR-3 ITGB3 ITGB3 DENND4C DENND4C LOC461877 LOC461877 LOC100609621 LOC100609621 ENSPTRP00000071015 ENSPTRP00000071015 NDEL1-2 NDEL1-2 CK820_G0032307 CK820_G0032307 PXN PXN INSRR INSRR MGARP MGARP LEP LEP PTPN2 PTPN2 AGTR2 AGTR2 SH2B2 SH2B2 ENSPTRP00000073414 ENSPTRP00000073414 GHRHR-2 GHRHR-2 LPIN1 LPIN1 ENSPTRP00000073578 ENSPTRP00000073578 ENSPTRP00000074085 ENSPTRP00000074085 ENSPTRP00000074154 ENSPTRP00000074154 GHR GHR PXN-2 PXN-2 SREBF1 SREBF1 PPARG PPARG SRC SRC PIK3R1 PIK3R1 ADCY8 ADCY8 SOGA1 SOGA1 RANGAP1 RANGAP1 LOC107971060 LOC107971060 ENSPTRP00000078445 ENSPTRP00000078445 FOS FOS CFLAR CFLAR CK820_G0040570 CK820_G0040570 IGF2 IGF2 ENSPTRP00000079016 ENSPTRP00000079016 LOC750927 LOC750927 LPIN3 LPIN3 MYO5A MYO5A BCAR1 BCAR1 IRS4 IRS4 RHOQ RHOQ ACTN2 ACTN2 CAMK2A CAMK2A ENSPTRP00000080400 ENSPTRP00000080400 CA2 CA2 ENSPTRP00000081061 ENSPTRP00000081061 CPEB1 CPEB1 GSK3B GSK3B JAK2 JAK2 ENSPTRP00000082322 ENSPTRP00000082322 AKT1 AKT1 BCAR3 BCAR3 CRK CRK ENSPTRP00000083456 ENSPTRP00000083456 PTK2 PTK2 NR4A3 NR4A3 SLC27A4 SLC27A4 PIK3CA PIK3CA ENSPTRP00000084830 ENSPTRP00000084830 PNPLA3-2 PNPLA3-2 ZNF106 ZNF106 ENSPTRP00000085929 ENSPTRP00000085929 ENSPTRP00000086173 ENSPTRP00000086173 ZDHHC7 ZDHHC7 RARRES2-2 RARRES2-2 CPS1 CPS1 SORBS1 SORBS1 HSF1 HSF1 MAX MAX ENSPTRP00000087943 ENSPTRP00000087943 RAB31 RAB31 NR4A2 NR4A2 CRHR2 CRHR2 CK820_G0040570-2 CK820_G0040570-2 STAT5B STAT5B ENSPTRP00000089297 ENSPTRP00000089297 EEF2K EEF2K AGTRAP AGTRAP AKT2 AKT2 PKM PKM LOC459393 LOC459393 RAB10 RAB10 PDPK1 PDPK1 CYP11A1 CYP11A1 INHBB INHBB STAT1 STAT1 TSHR TSHR ENSPTRP00000091157 ENSPTRP00000091157 STAT3 STAT3 CYBA CYBA ENSPTRP00000091906 ENSPTRP00000091906 CYSLTR2 CYSLTR2 EPRS1 EPRS1 C2CD5 C2CD5 ADCY6 ADCY6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ERRFI1ERBB receptor feedback inhibitor 1. (462 aa)
SLC25A33Solute carrier family 25, member 33; Belongs to the mitochondrial carrier (TC 2.A.29) family. (321 aa)
WDTC1WDTC1 isoform 4. (564 aa)
PCSK9Proprotein convertase subtilisin/kexin type 9; Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2 (LRP8/APOER2), and promotes their degradation in intracellular acidic compartments. Acts via a non-proteolytic mechanism to enhance the degradation of the hepatic LDLR through a clathrin LDLRAP1/ARH-mediated pathway. May prevent the recycling of LDLR from endosomes to [...] (813 aa)
JAK1Tyrosine-protein kinase. (1154 aa)
RPE65Retinoid isomerohydrolase RPE65. (533 aa)
HMGCS23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
ENSPTRP00000002048LOW QUALITY PROTEIN: putative gonadotropin-releasing hormone II receptor. (91 aa)
RAB13RAB13, member RAS oncogene family. (203 aa)
USF1Upstream transcription factor 1. (310 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (855 aa)
SLC30A10Solute carrier family 30 member 10. (485 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
ANKRD30AANKRD30A isoform 2. (1470 aa)
EIF4EBP2Eukaryotic translation initiation factor 4E binding protein 2. (120 aa)
GOT1Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] (413 aa)
PIK3C2APhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1686 aa)
CSRP3Cysteine and glycine rich protein 3. (194 aa)
MEN1MEN1 isoform 14. (615 aa)
UCP2Uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (309 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
SP1Sp1 transcription factor. (786 aa)
STAT6Signal transducer and activator of transcription. (847 aa)
SOCS2Suppressor of cytokine signaling 2. (198 aa)
PLA2G1BPhospholipase A(2). (148 aa)
KLKL isoform 1. (1012 aa)
FOXO1FOXO1 isoform 1. (655 aa)
RB1RB transcriptional corepressor 1. (928 aa)
TBC1D4TBC1D4 isoform 2. (1298 aa)
IRS2IRS2 isoform 1. (1340 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (640 aa)
SRSF5Serine and arginine rich splicing factor 5. (272 aa)
CK820_G0057069POTEH isoform 1. (522 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
CSKTyrosine-protein kinase. (450 aa)
IGF1RTyrosine-protein kinase receptor. (1364 aa)
ENSPTRP00000013791Coiled-coil domain-containing protein 144A-like isoform X2. (314 aa)
APRTAdenine phosphoribosyltransferase. (180 aa)
SLC2A4SLC2A4 isoform 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (466 aa)
NDEL1NudE nuclear distribution gene E homolog-like 1. (345 aa)
GLP2RGLP2R isoform 2; Belongs to the G-protein coupled receptor 2 family. (553 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (560 aa)
STAT5ASignal transducer and activator of transcription. (783 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1115 aa)
PDK2Protein-serine/threonine kinase. (407 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
BRIP1BRCA1 interacting protein C-terminal helicase 1. (1249 aa)
GH1Growth hormone variant; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. (271 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
LPIN2LPIN2 isoform 2. (896 aa)
RAB12RAB12, member RAS oncogene family. (244 aa)
RAB8ARAB8A, member RAS oncogene family. (207 aa)
PIK3R2Phosphoinositide-3-kinase, regulatory subunit 2 (Beta). (728 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
GSK3AGlycogen synthase kinase 3 alpha. (483 aa)
CEACAM1CEACAM1 isoform 3. (518 aa)
FGF21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
CYP1B1Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (543 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (699 aa)
INSIG2Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa)
LOC735535POTE ankyrin domain family member F. (611 aa)
GRB14Growth factor receptor-bound protein 14. (540 aa)
IRS1Insulin receptor substrate 1. (1241 aa)
CAPN10CAPN10 isoform 1; Belongs to the peptidase C2 family. (672 aa)
TRIB3TRIB3 isoform 4. (386 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
UMODL1UMODL1 isoform 3. (1445 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (832 aa)
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1. (1105 aa)
SLC26A6Solute carrier family 26, member 6. (761 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
APPL1Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1. (709 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (244 aa)
OTOP1OTOP1 isoform 1. (612 aa)
GNRHRGonadotropin releasing hormone receptor; Belongs to the G-protein coupled receptor 1 family. (328 aa)
NKX6-1NKX6-1 isoform 2. (367 aa)
NFKB1Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1. (969 aa)
CCNA2CCNA2 isoform 1; Belongs to the cyclin family. (432 aa)
GAB1GRB2-associated-binding protein 1. (724 aa)
POU4F2POU domain protein. (406 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
SRD5A13-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (259 aa)
MAP1BMicrotubule associated protein 1B. (2468 aa)
CRHBPCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
APCAdenomatous polyposis coli protein isoform X10. (2844 aa)
AP3S1Adaptor-related protein complex 3, sigma 1 subunit. (193 aa)
SPINK1Serine peptidase inhibitor, Kazal type 1. (79 aa)
EDN1EDN1 isoform 1. (212 aa)
GPLD1GPLD1 isoform 2. (840 aa)
GLP1RGlucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (463 aa)
GCLCGlutamate-cysteine ligase, catalytic subunit. (637 aa)
PHIPPHIP isoform 1. (1823 aa)
ARG1Arginase. (322 aa)
MAS1MAS1 isoform 1; Belongs to the G-protein coupled receptor 1 family. (325 aa)
HDAC9Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1066 aa)
IGFBP1IGFBP1 isoform 1. (281 aa)
POR-2NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (680 aa)
YWHAGTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide; Belongs to the 14-3-3 family. (247 aa)
PDK4Protein-serine/threonine kinase. (411 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
RARRES2Retinoic acid receptor responder (Tazarotene induced) 2. (163 aa)
INSIG1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (277 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (649 aa)
CYP11B1CYP11B1 isoform 5; Belongs to the cytochrome P450 family. (577 aa)
DNAI1Dynein axonemal intermediate chain 1. (703 aa)
FBP1Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (338 aa)
RABGAP1Rab GTPase-activating protein 1 isoform X1. (1085 aa)
SLC2A8Solute carrier family 2 member 8; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (477 aa)
ASS1Argininosuccinate synthetase 1. (412 aa)
SYAP1Synapse associated protein 1. (268 aa)
CPEB2Cytoplasmic polyadenylation element binding protein 2. (1036 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (448 aa)
GPTGlutamic--pyruvic transaminase. (496 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (652 aa)
CDK4Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
SLC29A2Solute carrier family 29 (Nucleoside transporters), member 2. (456 aa)
JAK3Tyrosine-protein kinase. (1124 aa)
NCOA5Nuclear receptor coactivator 5. (579 aa)
FN1FN1 isoform 1. (2477 aa)
POTEAPOTEA isoform 1. (539 aa)
GCKPhosphotransferase. (466 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (435 aa)
PRKDCProtein kinase, DNA-activated, catalytic polypeptide; Belongs to the PI3/PI4-kinase family. (4128 aa)
LYNTyrosine-protein kinase. (512 aa)
GPR173G protein-coupled receptor 173. (373 aa)
SLC22A12Solute carrier family 22 member 12. (553 aa)
SLC27A1Solute carrier family 27 (Fatty acid transporter), member 1. (646 aa)
TYK2Tyrosine-protein kinase. (1184 aa)
ENPP1ENPP1 isoform 1. (925 aa)
PNPLA3Patatin like phospholipase domain containing 3. (481 aa)
IDEInsulin-degrading enzyme; Belongs to the peptidase M16 family. (1019 aa)
SHC1SHC (Src homology 2 domain containing) transforming protein 1. (584 aa)
RAB15RAB15, member RAS onocogene family. (208 aa)
STXBP4Syntaxin binding protein 4. (553 aa)
FOXC2Forkhead box C2 (MFH-1, mesenchyme forkhead 1). (501 aa)
RAP1GDS1RAP1GDS1 isoform 18. (608 aa)
GH1-2Chorionic somatomammotropin A2. (222 aa)
RELAV-rel reticuloendotheliosis viral oncogene homolog A (Avian). (551 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (574 aa)
PTPRAReceptor-type tyrosine-protein phosphatase alpha. (802 aa)
TRARG1Trafficking regulator of GLUT4 (SLC2A4) 1. (177 aa)
GCGRGlucagon receptor; Belongs to the G-protein coupled receptor 2 family. (480 aa)
GRB10Growth factor receptor-bound protein 10. (594 aa)
FOXO4Forkhead box O4. (505 aa)
CAV2Caveolin-2; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (B [...] (162 aa)
SELENOSSELENOS isoform 5. (218 aa)
PDE3BPhosphodiesterase. (1113 aa)
ZFP36L1ZFP36 ring finger protein like 1. (338 aa)
ENSPTRP00000061612annotation not available (208 aa)
ENSPTRP00000062007SH2B adapter protein 2-like. (570 aa)
ENSPTRP00000062039annotation not available (397 aa)
INSRTyrosine-protein kinase receptor. (1408 aa)
AGTR1Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system (By similarity); Belongs to the G-protein coupled receptor 1 family. (394 aa)
LOC104002294LOW QUALITY PROTEIN: pyruvate kinase PKM-like. (501 aa)
GHRHRGrowth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (423 aa)
PIK3R3Phosphoinositide-3-kinase, regulatory subunit 3 (Gamma). (478 aa)
SLC39A14SLC39A14 isoform 1. (490 aa)
ENSPTRP00000064446annotation not available (116 aa)
NFE2L2Nuclear factor (Erythroid-derived 2)-like 2. (605 aa)
BAIAP2BAI1 associated protein 2. (553 aa)
CK820_G0011608CSH2 isoform 1. (199 aa)
XBP1XBP1 isoform 4. (381 aa)
AHCYL1Adenosylhomocysteinase. (499 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
FBN1FBN1 isoform 1. (2871 aa)
POR-3Cytochrome p450 oxidoreductase. (660 aa)
ITGB3Integrin beta-3 isoform X2. (837 aa)
DENND4CDENN domain containing 4C. (1958 aa)
LOC461877Argininosuccinate synthase pseudogene. (389 aa)
LOC100609621Argininosuccinate synthase pseudogene. (245 aa)
ENSPTRP00000071015annotation not available (408 aa)
NDEL1-2NudE nuclear distribution gene E homolog-like 1. (351 aa)
CK820_G0032307C15orf38-AP3S2 isoform 3. (154 aa)
PXNPXN isoform 20. (1078 aa)
INSRRTyrosine-protein kinase receptor. (1297 aa)
MGARPMitochondria localized glutamic acid rich protein. (240 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (167 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (421 aa)
AGTR2Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (363 aa)
SH2B2Uncharacterized protein. (677 aa)
ENSPTRP00000073414annotation not available (393 aa)
GHRHR-2Growth hormone-releasing hormone receptor isoform X1. (447 aa)
LPIN1LPIN1 isoform 7. (975 aa)
ENSPTRP00000073578annotation not available (588 aa)
ENSPTRP00000074085annotation not available (188 aa)
ENSPTRP00000074154annotation not available (111 aa)
GHRGrowth hormone receptor. (645 aa)
PXN-2PXN isoform 9. (1081 aa)
SREBF1SREBF1 isoform 6. (1177 aa)
PPARGPeroxisome proliferator-activated receptor gamma isoform X2. (505 aa)
SRCTyrosine-protein kinase. (542 aa)
PIK3R1Phosphoinositide-3-kinase, regulatory subunit 1 (Alpha). (724 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
SOGA1Suppressor of glucose, autophagy associated 1. (1657 aa)
RANGAP1RANGAP1 isoform 1. (610 aa)
LOC107971060SRD5A1 isoform 2. (141 aa)
ENSPTRP00000078445annotation not available (175 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
CFLARCASP8 and FADD-like apoptosis regulator; Belongs to the peptidase C14A family. (480 aa)
CK820_G0040570PRKCZ isoform 2. (457 aa)
IGF2Insulin like growth factor 2. (236 aa)
ENSPTRP00000079016annotation not available (160 aa)
LOC750927CCDC144A isoform 2. (1267 aa)
LPIN3LPIN3 isoform 2. (856 aa)
MYO5AMYO5A isoform 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1877 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (916 aa)
IRS4Insulin receptor substrate 4. (1257 aa)
RHOQRas homolog gene family, member Q. (205 aa)
ACTN2ACTN2 isoform 2. (894 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
ENSPTRP00000080400Ankyrin repeat domain-containing protein 36C-like. (82 aa)
CA2Carbonic anhydrase II; Belongs to the alpha-carbonic anhydrase family. (262 aa)
ENSPTRP00000081061annotation not available (107 aa)
CPEB1CPEB1 isoform 5. (626 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (481 aa)
JAK2Tyrosine-protein kinase. (1143 aa)
ENSPTRP00000082322annotation not available (82 aa)
AKT1AKT1 isoform 3; Belongs to the protein kinase superfamily. (480 aa)
BCAR3Breast cancer anti-estrogen resistance 3. (825 aa)
CRKV-crk sarcoma virus CT10 oncogene homolog (Avian). (304 aa)
ENSPTRP00000083456annotation not available (649 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1113 aa)
NR4A3Nuclear receptor subfamily 4 group A member 3. (637 aa)
SLC27A4Solute carrier family 27 (Fatty acid transporter), member 4. (646 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1034 aa)
ENSPTRP00000084830annotation not available (340 aa)
PNPLA3-2Patatin like phospholipase domain containing 3. (481 aa)
ZNF106Zinc finger protein 106 homolog. (1883 aa)
ENSPTRP00000085929annotation not available (241 aa)
ENSPTRP00000086173annotation not available (566 aa)
ZDHHC7Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (345 aa)
RARRES2-2Retinoic acid receptor responder 2. (163 aa)
CPS1Carbamoyl-phosphate synthase 1, mitochondrial. (1507 aa)
SORBS1Sorbin and SH3 domain containing 1. (1294 aa)
HSF1Heat shock transcription factor 1. (529 aa)
MAXMYC associated factor X. (162 aa)
ENSPTRP00000087943annotation not available (82 aa)
RAB31RAB31, member RAS oncogene family. (195 aa)
NR4A2Nuclear receptor subfamily 4, group A, member 2. (598 aa)
CRHR2Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. (438 aa)
CK820_G0040570-2PRKCZ isoform 4. (95 aa)
STAT5BSignal transducer and activator of transcription. (772 aa)
ENSPTRP00000089297annotation not available (265 aa)
EEF2KEukaryotic elongation factor 2 kinase. (725 aa)
AGTRAPAngiotensin II receptor-associated protein. (168 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (556 aa)
LOC459393Otopetrin-1-like. (563 aa)
RAB10RAB10, member RAS oncogene family. (200 aa)
PDPK13-phosphoinositide dependent protein kinase-1. (542 aa)
CYP11A1Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (521 aa)
INHBBInhibin subunit beta B. (407 aa)
STAT1Signal transducer and activator of transcription. (758 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
ENSPTRP00000091157annotation not available (617 aa)
STAT3Signal transducer and activator of transcription. (790 aa)
CYBACytochrome b-245 alpha chain. (210 aa)
ENSPTRP00000091906annotation not available (127 aa)
CYSLTR2Cysteinyl leukotriene receptor 2. (346 aa)
EPRS1EPRS isoform 1. (1515 aa)
C2CD5C2CD5 isoform 5. (1084 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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