Your Input: | |
| | ONECUT1 | One cut domain family member. (465 aa) |
| | ITGB6 | ITGB6 isoform 3. (701 aa) |
| | PXN-2 | PXN isoform 9. (1081 aa) |
| | FLCN | T0180863 isoform 1. (579 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (581 aa) |
| | ENSPTRP00000075374 | annotation not available (236 aa) |
| | ACVR1 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa) |
| | SRC | Tyrosine-protein kinase. (542 aa) |
| | FYN | Tyrosine-protein kinase. (537 aa) |
| | PDGFD | Platelet derived growth factor D. (370 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | PTPRK | Protein tyrosine phosphatase receptor type K. (1472 aa) |
| | LEFTY1 | Left-right determination factor. (366 aa) |
| | SMAD5 | Mothers against decapentaplegic homolog. (465 aa) |
| | STK16 | STK16 isoform 5. (349 aa) |
| | FERMT2 | Fermitin family member 2. (706 aa) |
| | ONECUT2 | One cut domain family member. (504 aa) |
| | ENSPTRP00000081537 | annotation not available (449 aa) |
| | CITED2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa) |
| | ITGB8 | Integrin beta; Belongs to the integrin beta chain family. (780 aa) |
| | CDKN2B | Cyclin-dependent kinase inhibitor 2B (P15, inhibits CDK4). (138 aa) |
| | CRK | V-crk sarcoma virus CT10 oncogene homolog (Avian). (304 aa) |
| | PTK2 | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1113 aa) |
| | PDCD5 | Programmed cell death 5. (129 aa) |
| | SPI1 | Spi-1 proto-oncogene. (270 aa) |
| | ITGB8-2 | Integrin subunit beta 8. (780 aa) |
| | GCNT2 | Glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group). (402 aa) |
| | GDF9-2 | Growth differentiation factor 9. (455 aa) |
| | WFIKKN2 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (576 aa) |
| | ID1-2 | Inhibitor of DNA binding 1, HLH protein. (155 aa) |
| | ITGA8 | Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | NPNT | NPNT isoform 10. (611 aa) |
| | ENSPTRP00000089450 | annotation not available (303 aa) |
| | MEF2C | Myocyte enhancer factor 2C. (483 aa) |
| | YES1 | Tyrosine-protein kinase. (558 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (442 aa) |
| | PSG9 | Pregnancy-specific beta-1-glycoprotein 9 isoform X1. (426 aa) |
| | STAT3 | Signal transducer and activator of transcription. (790 aa) |
| | ENSPTRP00000091683 | annotation not available (342 aa) |
| | LOC459477 | T0188211 isoform 1. (343 aa) |
| | LPXN | Leupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (391 aa) |
| | OVOL2 | Ovo like zinc finger 2. (275 aa) |
| | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (508 aa) |
| | CHST11 | Carbohydrate sulfotransferase. (352 aa) |
| | ADAM9 | ADAM metallopeptidase domain 9. (819 aa) |
| | SIRT1-2 | Sirtuin 1. (751 aa) |
| | SKI | V-ski sarcoma viral oncogene homolog (Avian). (736 aa) |
| | ZFYVE9 | Zinc finger FYVE domain-containing protein. (1425 aa) |
| | DDR2 | Discoidin domain receptor tyrosine kinase 2. (855 aa) |
| | FMOD | FMOD isoform 1. (376 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | PARP1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa) |
| | BAMBI | BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa) |
| | SIRT1 | SIRT1 isoform 2. (751 aa) |
| | NODAL | NODAL isoform 2. (347 aa) |
| | ZMIZ1 | Zinc finger, MIZ-type containing 1. (1073 aa) |
| | BMPR1A | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa) |
| | ANKRD1 | Ankyrin repeat domain 1 (Cardiac muscle). (319 aa) |
| | FGFR2 | Fibroblast growth factor receptor. (841 aa) |
| | FSHB | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. (129 aa) |
| | LTBP3 | Latent transforming growth factor beta binding protein 3. (1297 aa) |
| | SOX5 | SRY (Sex determining region Y)-box 5. (765 aa) |
| | ACVRL1 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa) |
| | AMHR2 | Anti-Muellerian hormone type-2 receptor; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. (573 aa) |
| | APPL2 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (671 aa) |
| | PPM1A | Protein phosphatase, Mg2+/Mn2+ dependent 1A. (455 aa) |
| | FUT8 | Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. (575 aa) |
| | TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) |
| | CILP | Cartilage intermediate layer protein. (1184 aa) |
| | SMAD6 | Mothers against decapentaplegic homolog. (496 aa) |
| | PML | PML isoform 6. (836 aa) |
| | FURIN | Furin (Paired basic amino acid cleaving enzyme); Belongs to the peptidase S8 family. (794 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1364 aa) |
| | CDH5 | CDH5 isoform 1; Cadherins are calcium-dependent cell adhesion proteins. (784 aa) |
| | WWOX | WW domain containing oxidoreductase. (414 aa) |
| | ARRB2 | ARRB2 isoform 2. (430 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa) |
| | MAPK7 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (816 aa) |
| | NLK | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa) |
| | COL1A1 | Collagen type I alpha 1 chain. (1464 aa) |
| | MTMR4 | Myotubularin related protein 4. (1195 aa) |
| | SOX9 | Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa) |
| | TWSG1 | Twisted gastrulation BMP signaling modulator 1. (223 aa) |
| | SMAD7 | Mothers against decapentaplegic homolog. (491 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (552 aa) |
| | GDF15 | Growth differentiation factor 15. (308 aa) |
| | LTBP4 | Latent transforming growth factor beta binding protein 4. (1622 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | LOC737606 | T0172536 isoform 1. (398 aa) |
| | COL3A1 | Collagen type III alpha 1 chain. (1466 aa) |
| | MSTN | Growth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth; Belongs to the TGF-beta family. (376 aa) |
| | WNT10A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa) |
| | GDF5 | GDF5 isoform 1. (501 aa) |
| | CLEC3B | C-type lectin domain family 3, member B. (202 aa) |
| | APPL1 | Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1. (709 aa) |
| | CLDN1 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa) |
| | NRROS | Negative regulator of reactive oxygen species. (692 aa) |
| | PAK2 | Non-specific serine/threonine protein kinase. (476 aa) |
| | SMAD1 | Mothers against decapentaplegic homolog. (469 aa) |
| | HPGD | 15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa) |
| | GDF9 | Growth differentiation factor 9. (455 aa) |
| | NR3C1 | NR3C1 isoform 5. (778 aa) |
| | EDN1 | EDN1 isoform 1. (212 aa) |
| | ARG1 | Arginase. (322 aa) |
| | COL1A2 | Collagen type I alpha 2 chain. (1366 aa) |
| | CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa) |
| | WNT2 | Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa) |
| | HIPK2 | Homeodomain interacting protein kinase 2. (1198 aa) |
| | ZYX | ZYX isoform 1. (572 aa) |
| | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha. (386 aa) |
| | PENK | PENK isoform 3. (267 aa) |
| | FOXH1 | FOXH1 isoform 1. (365 aa) |
| | ENG | ENG isoform 1. (658 aa) |
| | CITED1 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (219 aa) |
| | USP9Y | USP9Y isoform 1; Belongs to the peptidase C19 family. (2523 aa) |
| | DLX1 | Distal-less homeobox 1. (255 aa) |
| | GDF10 | Bone morphogenetic protein 3; Belongs to the TGF-beta family. (477 aa) |
| | FN1 | FN1 isoform 1. (2477 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa) |
| | PDE3A | Phosphodiesterase. (1141 aa) |
| | SOX6 | SOX6 isoform 9. (828 aa) |
| | CRKL | V-crk sarcoma virus CT10 oncogene homolog (Avian)-like. (303 aa) |
| | HYAL2 | Hyaluronidase. (473 aa) |
| | PDE2A | Phosphodiesterase. (941 aa) |
| | HDAC2 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (581 aa) |
| | ITGB5 | Integrin beta; Belongs to the integrin beta chain family. (799 aa) |
| | FOXH1-2 | Forkhead box H1. (365 aa) |
| | SFRP1 | Secreted frizzled-related protein 1. (314 aa) |
| | CX3CR1 | C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (387 aa) |
| | SMAD9 | Mothers against decapentaplegic homolog. (467 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | COL4A2 | Collagen type IV alpha 2 chain. (1711 aa) |
| | ID1 | Inhibitor of DNA binding 1, dominant negative helix-loop-helix protein. (155 aa) |
| | EID2 | EP300 interacting inhibitor of differentiation 2. (236 aa) |
| | CAV2 | Caveolin-2; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (B [...] (162 aa) |
| | ZFP36L1 | ZFP36 ring finger protein like 1. (338 aa) |
| | ENSPTRP00000061448 | annotation not available (572 aa) |
| | CK820_G0012168 | ABL1 isoform 3. (1149 aa) |
| | EPB41L5 | Erythrocyte membrane protein band 4.1 like 5. (733 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (467 aa) |
| | ZEB1 | Zinc finger E-box binding homeobox 1. (1127 aa) |
| | ENSPTRP00000063212 | annotation not available (75 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) |
| | ENSPTRP00000064416 | annotation not available (502 aa) |
| | WNT7A | Protein Wnt-7a; Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta- catenin signaling pathway (By similarity). Plays an important role in embryonic development, including dorsal versus ventral patterning during limb development, skeleton development and urogenital tract development. Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation (By similarity). Required for normal, sexually dimorphic development of the Mullerian ducts, and for normal fertility in both sexes. Required for normal [...] (349 aa) |
| | TGFBR3L | TGFBR3L isoform 1. (313 aa) |
| | TGFBR3 | Transforming growth factor, beta receptor III. (861 aa) |
| | LTBP2 | Latent transforming growth factor beta binding protein 2. (1821 aa) |
| | ZFP36L2 | Zinc finger protein 36, C3H type-like 2. (492 aa) |
| | LOC452254 | LOW QUALITY PROTEIN: disintegrin and metalloproteinase domain-containing protein 1-like. (863 aa) |
| | FBN1 | FBN1 isoform 1. (2871 aa) |
| | LRRC32 | Leucine rich repeat containing 32. (662 aa) |
| | USP9X | Ubiquitin specific peptidase 9, X-linked; Belongs to the peptidase C19 family. (2591 aa) |
| | DUSP22 | Dual specificity phosphatase 22; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (205 aa) |
| | GLG1 | Golgi glycoprotein 1. (1203 aa) |
| | SKIL | SKI like proto-oncogene. (684 aa) |
| | PXN | PXN isoform 20. (1078 aa) |
| | DAB2 | Disabled homolog 2, mitogen-responsive phosphoprotein. (770 aa) |
| | TGFBRAP1 | Transforming growth factor, beta receptor associated protein 1. (860 aa) |
| | ABL1 | Tyrosine-protein kinase. (1149 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa) |
| | ENSPTRP00000073126 | annotation not available (296 aa) |
| | SCX | Scleraxis bHLH transcription factor. (201 aa) |
| | USP15 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa) |
