16 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SP1	Sp1 transcription factor. (786 aa)
	PRRX1	Paired related homeobox 1. (245 aa)
	EGR2	Early growth response 2. (476 aa)
	TCF12	Transcription factor 12. (706 aa)
	MEOX1	Homeobox protein MOX-1; Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints. Binds specifically to the promoter of target genes and regulates their expression. Activates expression of NKX3-2 in the sclerotome. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independen [...] (254 aa)
	DLX5	Distal-less homeobox 5. (289 aa)
	GATA3	GATA binding protein 3. (444 aa)
	PAX6	PAX6 isoform 13. (436 aa)
	HOXA3	HOXA3 isoform 3. (443 aa)
	OLIG2	OLIG2 isoform 1. (323 aa)
	HOXA3-2	Homeobox A3. (443 aa)
	HOXC4	HOXC4 isoform 1. (264 aa)
	POU3F3	POU domain protein. (476 aa)
	ENSPTRP00000079007	annotation not available (323 aa)
	ALX4	ALX homeobox 4. (411 aa)
	PAX3	PAX3 isoform 4. (505 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALX4	DLX5	ENSPTRP00000083300	ENSPTRP00000033230	ALX homeobox 4.	Distal-less homeobox 5.	0.401
DLX5	ALX4	ENSPTRP00000033230	ENSPTRP00000083300	Distal-less homeobox 5.	ALX homeobox 4.	0.401
EGR2	GATA3	ENSPTRP00000004374	ENSPTRP00000064658	Early growth response 2.	GATA binding protein 3.	0.534
EGR2	TCF12	ENSPTRP00000004374	ENSPTRP00000012156	Early growth response 2.	Transcription factor 12.	0.456
ENSPTRP00000079007	PAX6	ENSPTRP00000079007	ENSPTRP00000065705	annotation not available	PAX6 isoform 13.	0.578
GATA3	EGR2	ENSPTRP00000064658	ENSPTRP00000004374	GATA binding protein 3.	Early growth response 2.	0.534
GATA3	TCF12	ENSPTRP00000064658	ENSPTRP00000012156	GATA binding protein 3.	Transcription factor 12.	0.617
OLIG2	PAX6	ENSPTRP00000069533	ENSPTRP00000065705	OLIG2 isoform 1.	PAX6 isoform 13.	0.672
PAX6	ENSPTRP00000079007	ENSPTRP00000065705	ENSPTRP00000079007	PAX6 isoform 13.	annotation not available	0.578
PAX6	OLIG2	ENSPTRP00000065705	ENSPTRP00000069533	PAX6 isoform 13.	OLIG2 isoform 1.	0.672
TCF12	EGR2	ENSPTRP00000012156	ENSPTRP00000004374	Transcription factor 12.	Early growth response 2.	0.456
TCF12	GATA3	ENSPTRP00000012156	ENSPTRP00000064658	Transcription factor 12.	GATA binding protein 3.	0.617