STRINGSTRING
EDN1 EDN1 QRFP QRFP PYY PYY UCN3 UCN3 POMC POMC MRAP MRAP SPX SPX GNAS GNAS APELA APELA LOC104003639 LOC104003639 SHANK1 SHANK1 ENSPTRP00000067301 ENSPTRP00000067301 EDN3 EDN3 PRLH PRLH CCKBR CCKBR NMU NMU TAC1 TAC1 ENSPTRP00000087048 ENSPTRP00000087048 PMCHL1 PMCHL1 ENSPTRP00000092281 ENSPTRP00000092281 TAC3 TAC3 GNAO1 GNAO1 NPPA NPPA EDN2 EDN2 KISS1 KISS1 GAL GAL NTS NTS PMCH PMCH NMB NMB AGRP AGRP HCRT HCRT PPY PPY TAC4 TAC4 ADCYAP1 ADCYAP1 UCN UCN ASIP ASIP GHRH GHRH MRAP2 MRAP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EDN1EDN1 isoform 1. (212 aa)
QRFPQRFP isoform 1. (136 aa)
PYYPYY isoform 1. (95 aa)
UCN3UCN3 isoform 1. (161 aa)
POMCProopiomelanocortin. (268 aa)
MRAPMelanocortin-2 receptor accessory protein; Modulator of melanocortin receptors (MC1R, MC2R, MC3R, MC4R and MC5R). Acts by increasing ligand-sensitivity of melanocortin receptors and enhancing generation of cAMP by the receptors. Required both for MC2R trafficking to the cell surface of adrenal cells and for signaling in response to corticotropin (ACTH). May be involved in the intracellular trafficking pathways in adipocyte cells (By similarity). Belongs to the MRAP family. (172 aa)
SPXChromosome 12 open reading frame 39. (116 aa)
GNASGNAS isoform 19. (1042 aa)
APELAApelin receptor early endogenous ligand. (54 aa)
LOC104003639Guanine nucleotide-binding protein G(s) subunit alpha. (245 aa)
SHANK1SHANK1 isoform 3. (2161 aa)
ENSPTRP00000067301annotation not available (92 aa)
EDN3EDN3 isoform 1. (238 aa)
PRLHProlactin releasing hormone. (87 aa)
CCKBRCholecystokinin B receptor; Belongs to the G-protein coupled receptor 1 family. (514 aa)
NMUNMU isoform 2. (174 aa)
TAC1TAC1 isoform 1. (134 aa)
ENSPTRP00000087048annotation not available (82 aa)
PMCHL1Pro-MCH variant; Belongs to the melanin-concentrating hormone family. (82 aa)
ENSPTRP00000092281annotation not available (136 aa)
TAC3TAC3 isoform 1. (121 aa)
GNAO1G protein subunit alpha o1. (354 aa)
NPPANatriuretic peptide A. (153 aa)
EDN2EDN2 isoform 1. (178 aa)
KISS1KISS1 isoform 2. (138 aa)
GALGalanin and GMAP prepropeptide. (123 aa)
NTSNTS isoform 1. (170 aa)
PMCHPro-MCH. (165 aa)
NMBNMB isoform 1. (154 aa)
AGRPAgouti related neuropeptide. (132 aa)
HCRTOrexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family. (130 aa)
PPYPancreatic polypeptide. (95 aa)
TAC4TAC4 isoform 4. (113 aa)
ADCYAP1Adenylate cyclase activating polypeptide 1. (176 aa)
UCNUCN isoform 1. (124 aa)
ASIPAgouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity). (132 aa)
GHRHGrowth hormone releasing hormone. (108 aa)
MRAP2Melanocortin 2 receptor accessory protein 2. (205 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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