12 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PODXL	Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family. (556 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	NPHS2	NPHS2 stomatin family member, podocin. (383 aa)
	JAG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
	IQGAP1	IQ motif containing GTPase activating protein 1. (1657 aa)
	MYO1E	MYO1E isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1108 aa)
	LAMB2	Laminin, beta 2 (Laminin S). (1798 aa)
	MAGI2	Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1283 aa)
	NPHS1	NPHS1 isoform 1. (1241 aa)
	ASXL1	ASXL transcriptional regulator 1. (1548 aa)
	NOTCH2	NOTCH2 isoform 1. (2612 aa)
	BMP4-2	Bone morphogenetic protein 4. (408 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IQGAP1	NPHS1	ENSPTRP00000012743	ENSPTRP00000061965	IQ motif containing GTPase activating protein 1.	NPHS1 isoform 1.	0.822
IQGAP1	NPHS2	ENSPTRP00000012743	ENSPTRP00000002886	IQ motif containing GTPase activating protein 1.	NPHS2 stomatin family member, podocin.	0.463
JAG1	NOTCH2	ENSPTRP00000022729	ENSPTRP00000075807	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	NOTCH2 isoform 1.	0.994
MAGI2	NPHS1	ENSPTRP00000033085	ENSPTRP00000061965	Membrane associated guanylate kinase, WW and PDZ domain containing 2.	NPHS1 isoform 1.	0.531
MYO1E	NPHS2	ENSPTRP00000012180	ENSPTRP00000002886	MYO1E isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	NPHS2 stomatin family member, podocin.	0.462
NOTCH2	JAG1	ENSPTRP00000075807	ENSPTRP00000022729	NOTCH2 isoform 1.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.994
NPHS1	IQGAP1	ENSPTRP00000061965	ENSPTRP00000012743	NPHS1 isoform 1.	IQ motif containing GTPase activating protein 1.	0.822
NPHS1	MAGI2	ENSPTRP00000061965	ENSPTRP00000033085	NPHS1 isoform 1.	Membrane associated guanylate kinase, WW and PDZ domain containing 2.	0.531
NPHS1	NPHS2	ENSPTRP00000061965	ENSPTRP00000002886	NPHS1 isoform 1.	NPHS2 stomatin family member, podocin.	0.961
NPHS1	PODXL	ENSPTRP00000061965	ENSPTRP00000073254	NPHS1 isoform 1.	Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family.	0.696
NPHS2	IQGAP1	ENSPTRP00000002886	ENSPTRP00000012743	NPHS2 stomatin family member, podocin.	IQ motif containing GTPase activating protein 1.	0.463
NPHS2	MYO1E	ENSPTRP00000002886	ENSPTRP00000012180	NPHS2 stomatin family member, podocin.	MYO1E isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.462
NPHS2	NPHS1	ENSPTRP00000002886	ENSPTRP00000061965	NPHS2 stomatin family member, podocin.	NPHS1 isoform 1.	0.961
NPHS2	PODXL	ENSPTRP00000002886	ENSPTRP00000073254	NPHS2 stomatin family member, podocin.	Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family.	0.721
PODXL	NPHS1	ENSPTRP00000073254	ENSPTRP00000061965	Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family.	NPHS1 isoform 1.	0.696
PODXL	NPHS2	ENSPTRP00000073254	ENSPTRP00000002886	Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family.	NPHS2 stomatin family member, podocin.	0.721