13 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	WNK4	WNK lysine deficient protein kinase 4. (1282 aa)
	PKD2	Polycystin 2, transient receptor potential cation channel. (968 aa)
	KLHL3	Kelch like family member 3. (608 aa)
	CALB1	CALB1 isoform 3. (261 aa)
	NOTCH1	NOTCH1 isoform 1. (2555 aa)
	CK820_G0056924	NPIPA2 isoform 1. (277 aa)
	POU3F3	POU domain protein. (476 aa)
	UMOD	UMOD isoform 1. (690 aa)
	TFAP2B	Transcription factor AP-2 beta. (467 aa)
	CK820_G0054628	PKD1 isoform 4. (3384 aa)
	PAX8	PAX8 isoform 1. (456 aa)
	PAX2	PAX2 isoform 1. (417 aa)
	JAG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CK820_G0054628	CK820_G0056924	ENSPTRP00000083743	ENSPTRP00000064672	PKD1 isoform 4.	NPIPA2 isoform 1.	0.444
CK820_G0054628	PKD2	ENSPTRP00000083743	ENSPTRP00000027941	PKD1 isoform 4.	Polycystin 2, transient receptor potential cation channel.	0.997
CK820_G0056924	CK820_G0054628	ENSPTRP00000064672	ENSPTRP00000083743	NPIPA2 isoform 1.	PKD1 isoform 4.	0.444
CK820_G0056924	PKD2	ENSPTRP00000064672	ENSPTRP00000027941	NPIPA2 isoform 1.	Polycystin 2, transient receptor potential cation channel.	0.962
JAG1	NOTCH1	ENSPTRP00000022729	ENSPTRP00000036924	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	NOTCH1 isoform 1.	0.999
KLHL3	WNK4	ENSPTRP00000029536	ENSPTRP00000015697	Kelch like family member 3.	WNK lysine deficient protein kinase 4.	0.939
NOTCH1	JAG1	ENSPTRP00000036924	ENSPTRP00000022729	NOTCH1 isoform 1.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.999
PKD2	CK820_G0054628	ENSPTRP00000027941	ENSPTRP00000083743	Polycystin 2, transient receptor potential cation channel.	PKD1 isoform 4.	0.997
PKD2	CK820_G0056924	ENSPTRP00000027941	ENSPTRP00000064672	Polycystin 2, transient receptor potential cation channel.	NPIPA2 isoform 1.	0.962
WNK4	KLHL3	ENSPTRP00000015697	ENSPTRP00000029536	WNK lysine deficient protein kinase 4.	Kelch like family member 3.	0.939