15 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FMN1	FMN1 isoform 1. (1425 aa)
	PAX8	PAX8 isoform 1. (456 aa)
	BMP4-2	Bone morphogenetic protein 4. (408 aa)
	WNT4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
	ENSPTRP00000069764	annotation not available (1213 aa)
	SMO-2	Smoothened, frizzled class receptor. (786 aa)
	GDNF	Glial cell derived neurotrophic factor. (228 aa)
	CTNNB1	Catenin (Cadherin-associated protein), beta 1, 88kDa. (781 aa)
	SMO	SMO isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
	SIX2	SIX homeobox 2. (291 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	KIF26B	KIF26B isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2108 aa)
	SALL1	SALL1 isoform 2. (1326 aa)
	LHX1	LIM/homeobox protein Lhx1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis (By similarity). (406 aa)
	PAX2	PAX2 isoform 1. (417 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	CTNNB1	ENSPTRP00000010780	ENSPTRP00000044466	Bone morphogenetic protein 4.	Catenin (Cadherin-associated protein), beta 1, 88kDa.	0.551
BMP4-2	CTNNB1	ENSPTRP00000080656	ENSPTRP00000044466	Bone morphogenetic protein 4.	Catenin (Cadherin-associated protein), beta 1, 88kDa.	0.551
CTNNB1	BMP4	ENSPTRP00000044466	ENSPTRP00000010780	Catenin (Cadherin-associated protein), beta 1, 88kDa.	Bone morphogenetic protein 4.	0.551
CTNNB1	BMP4-2	ENSPTRP00000044466	ENSPTRP00000080656	Catenin (Cadherin-associated protein), beta 1, 88kDa.	Bone morphogenetic protein 4.	0.551
CTNNB1	SMO	ENSPTRP00000044466	ENSPTRP00000033707	Catenin (Cadherin-associated protein), beta 1, 88kDa.	SMO isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family.	0.479
CTNNB1	SMO-2	ENSPTRP00000044466	ENSPTRP00000067533	Catenin (Cadherin-associated protein), beta 1, 88kDa.	Smoothened, frizzled class receptor.	0.479
CTNNB1	WNT4	ENSPTRP00000044466	ENSPTRP00000063328	Catenin (Cadherin-associated protein), beta 1, 88kDa.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.753
ENSPTRP00000069764	SIX2	ENSPTRP00000069764	ENSPTRP00000020407	annotation not available	SIX homeobox 2.	0.579
LHX1	PAX2	ENSPTRP00000054548	ENSPTRP00000091068	LIM/homeobox protein Lhx1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis (By similarity).	PAX2 isoform 1.	0.651
LHX1	PAX8	ENSPTRP00000054548	ENSPTRP00000085551	LIM/homeobox protein Lhx1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis (By similarity).	PAX8 isoform 1.	0.538
LHX1	SIX2	ENSPTRP00000054548	ENSPTRP00000020407	LIM/homeobox protein Lhx1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis (By similarity).	SIX homeobox 2.	0.503
LHX1	WNT4	ENSPTRP00000054548	ENSPTRP00000063328	LIM/homeobox protein Lhx1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis (By similarity).	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.497
PAX2	LHX1	ENSPTRP00000091068	ENSPTRP00000054548	PAX2 isoform 1.	LIM/homeobox protein Lhx1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis (By similarity).	0.651
PAX2	SALL1	ENSPTRP00000091068	ENSPTRP00000064582	PAX2 isoform 1.	SALL1 isoform 2.	0.497
PAX2	SIX2	ENSPTRP00000091068	ENSPTRP00000020407	PAX2 isoform 1.	SIX homeobox 2.	0.657
PAX2	WNT4	ENSPTRP00000091068	ENSPTRP00000063328	PAX2 isoform 1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.472
PAX8	LHX1	ENSPTRP00000085551	ENSPTRP00000054548	PAX8 isoform 1.	LIM/homeobox protein Lhx1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis (By similarity).	0.538
PAX8	SIX2	ENSPTRP00000085551	ENSPTRP00000020407	PAX8 isoform 1.	SIX homeobox 2.	0.463
SALL1	PAX2	ENSPTRP00000064582	ENSPTRP00000091068	SALL1 isoform 2.	PAX2 isoform 1.	0.497
SALL1	SIX2	ENSPTRP00000064582	ENSPTRP00000020407	SALL1 isoform 2.	SIX homeobox 2.	0.579