STRINGSTRING
NOTCH1 NOTCH1 SOSTDC1-2 SOSTDC1-2 RBPJ RBPJ NR2F2 NR2F2 ACVR1 ACVR1 ARX ARX SOSTDC1 SOSTDC1 HOXA13 HOXA13 RARA RARA PROX1 PROX1 HOXA13-2 HOXA13-2 DLL1 DLL1 SPDEF SPDEF NKX2-2 NKX2-2 NRP1 NRP1 PDPN PDPN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NOTCH1NOTCH1 isoform 1. (2555 aa)
SOSTDC1-2Sclerostin domain containing 1. (206 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (500 aa)
NR2F2Nuclear receptor subfamily 2, group F, member 2. (414 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
ARXARX isoform 1. (559 aa)
SOSTDC1Sclerostin domain containing 1. (230 aa)
HOXA13Homeobox A13. (388 aa)
RARARARA isoform 4. (624 aa)
PROX1Prospero homeobox 1. (737 aa)
HOXA13-2HOXA13 isoform 1. (388 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
SPDEFSAM pointed domain containing ETS transcription factor. (335 aa)
NKX2-2NKX2-2 isoform 1. (273 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
PDPNPDPN isoform 3. (238 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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