15 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DLG5	Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1919 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	AKR1B1	Aldo-keto reductase family 1, member B1 (Aldose reductase). (316 aa)
	WNT7B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
	PAX2	PAX2 isoform 1. (417 aa)
	PTCH1	PTCH1 isoform 8. (1428 aa)
	LOC743215	AKR1B1 isoform 13. (294 aa)
	CK820_G0054628	PKD1 isoform 4. (3384 aa)
	BMP4-2	Bone morphogenetic protein 4. (408 aa)
	CK820_G0056924	NPIPA2 isoform 1. (277 aa)
	ENSPTRP00000067500	annotation not available (264 aa)
	ENSPTRP00000070319	annotation not available (244 aa)
	AQP2	AQP2 isoform 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
	CALB1	CALB1 isoform 3. (261 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	PTCH1	ENSPTRP00000010780	ENSPTRP00000087586	Bone morphogenetic protein 4.	PTCH1 isoform 8.	0.454
BMP4	SHH	ENSPTRP00000010780	ENSPTRP00000075730	Bone morphogenetic protein 4.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.720
BMP4-2	PTCH1	ENSPTRP00000080656	ENSPTRP00000087586	Bone morphogenetic protein 4.	PTCH1 isoform 8.	0.454
BMP4-2	SHH	ENSPTRP00000080656	ENSPTRP00000075730	Bone morphogenetic protein 4.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.720
CK820_G0054628	CK820_G0056924	ENSPTRP00000083743	ENSPTRP00000064672	PKD1 isoform 4.	NPIPA2 isoform 1.	0.444
CK820_G0056924	CK820_G0054628	ENSPTRP00000064672	ENSPTRP00000083743	NPIPA2 isoform 1.	PKD1 isoform 4.	0.444
PAX2	SHH	ENSPTRP00000091068	ENSPTRP00000075730	PAX2 isoform 1.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.479
PTCH1	BMP4	ENSPTRP00000087586	ENSPTRP00000010780	PTCH1 isoform 8.	Bone morphogenetic protein 4.	0.454
PTCH1	BMP4-2	ENSPTRP00000087586	ENSPTRP00000080656	PTCH1 isoform 8.	Bone morphogenetic protein 4.	0.454
PTCH1	SHH	ENSPTRP00000087586	ENSPTRP00000075730	PTCH1 isoform 8.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.999
SHH	BMP4	ENSPTRP00000075730	ENSPTRP00000010780	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Bone morphogenetic protein 4.	0.720
SHH	BMP4-2	ENSPTRP00000075730	ENSPTRP00000080656	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Bone morphogenetic protein 4.	0.720
SHH	PAX2	ENSPTRP00000075730	ENSPTRP00000091068	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	PAX2 isoform 1.	0.479
SHH	PTCH1	ENSPTRP00000075730	ENSPTRP00000087586	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	PTCH1 isoform 8.	0.999
SHH	WNT7B	ENSPTRP00000075730	ENSPTRP00000063618	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.401
WNT7B	SHH	ENSPTRP00000063618	ENSPTRP00000075730	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.401