STRINGSTRING
IHH IHH OSR1 OSR1 SHOX2 SHOX2 OSR2 OSR2 HOXC11 HOXC11 NOG NOG BMP4 BMP4 WNT9A WNT9A COL2A1 COL2A1 CTNNB1 CTNNB1 ENSPTRP00000077262 ENSPTRP00000077262 BMP4-2 BMP4-2 EXT1 EXT1 HOXA11 HOXA11 HYAL1 HYAL1 BMP7 BMP7 SLC2A10 SLC2A10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
OSR1Odd-skipped related transcription factor 1. (266 aa)
SHOX2SHOX2 isoform 2. (343 aa)
OSR2Protein odd-skipped-related 2 isoform X4. (433 aa)
HOXC11HOXC11 isoform 1. (304 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
COL2A1Collagen type II alpha 1 chain. (1487 aa)
CTNNB1Catenin (Cadherin-associated protein), beta 1, 88kDa. (781 aa)
ENSPTRP00000077262annotation not available (314 aa)
BMP4-2Bone morphogenetic protein 4. (408 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
HOXA11HOXA11 isoform 2. (313 aa)
HYAL1Hyaluronidase. (435 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
SLC2A10Solute carrier family 2 (Facilitated glucose transporter), member 10; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (541 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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