STRINGSTRING
F2 F2 C1QC C1QC FCN3 FCN3 OAZ3 OAZ3 CD5L CD5L APCS APCS SERPINC1 SERPINC1 C4BPA C4BPA HPX HPX ENSPTRP00000093626 ENSPTRP00000093626 SERPINF2 SERPINF2 ITIH4 ITIH4 ENSPTRP00000089678 ENSPTRP00000089678 ENSPTRP00000089475 ENSPTRP00000089475 ENSPTRP00000088582 ENSPTRP00000088582 SERPING1 SERPING1 MSN MSN INTS11 INTS11 ENSPTRP00000086563 ENSPTRP00000086563 CK820_G0055133 CK820_G0055133 JCHAIN JCHAIN ACTG2 ACTG2 FGG FGG STOM STOM ENSPTRP00000082975 ENSPTRP00000082975 LOC472599 LOC472599 LOC748740 LOC748740 ENSPTRP00000081955 ENSPTRP00000081955 DNPEP DNPEP TMPRSS13 TMPRSS13 GRIPAP1 GRIPAP1 HSPA2 HSPA2 ACTG1 ACTG1 LOC100615440 LOC100615440 GC GC PZP PZP EIF2A EIF2A ITIH2 ITIH2 SLC2A1 SLC2A1 LOC100611246 LOC100611246 LOC743313 LOC743313 HSPA8 HSPA8 YWHAZ YWHAZ ENSPTRP00000074124 ENSPTRP00000074124 ENSPTRP00000072249 ENSPTRP00000072249 LOC739666 LOC739666 ENSPTRP00000070878 ENSPTRP00000070878 ENSPTRP00000070303 ENSPTRP00000070303 ACSM1 ACSM1 LOC462577-2 LOC462577-2 HP HP ITIH1 ITIH1 F13A1 F13A1 KNG1 KNG1 LOC100616513 LOC100616513 LOC462577 LOC462577 SDCBP SDCBP ENSPTRP00000062406 ENSPTRP00000062406 LOC460532 LOC460532 HPR HPR ENSPTRP00000060619 ENSPTRP00000060619 LOC745166 LOC745166 A2M A2M PSMC5 PSMC5 ALB ALB CK820_G0040173 CK820_G0040173 C1S C1S C1R C1R ZBTB38 ZBTB38 CPN2 CPN2 HSPA1L HSPA1L TFRC TFRC CFHR1 CFHR1 A1BG A1BG ENG ENG GSN GSN ORM2 ORM2 AMBP AMBP CLU CLU PON1 PON1 PLG PLG CLIC1 CLIC1 C9 C9 FGA FGA FGB FGB ANXA5 ANXA5 AFM AFM HRG HRG BCHE BCHE CP CP PROS1 PROS1 TGFB1 TGFB1 ZNF177 ZNF177 ANGPTL4 ANGPTL4 C3 C3 LGALS3BP LGALS3BP ITGA2B ITGA2B SLC4A1 SLC4A1 PFN1 PFN1 CIB2 CIB2 SERPINA3 SERPINA3 C1RL C1RL APOA4 APOA4 KDM4D KDM4D
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (622 aa)
C1QCComplement C1q C chain. (245 aa)
FCN3FCN3 isoform 1. (212 aa)
OAZ3Ornithine decarboxylase antizyme 3. (235 aa)
CD5LCD5 molecule like. (347 aa)
APCSPentaxin. (223 aa)
SERPINC1Serpin family C member 1; Belongs to the serpin family. (464 aa)
C4BPAComplement component 4 binding protein alpha. (597 aa)
HPXHemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. (462 aa)
ENSPTRP00000093626annotation not available (450 aa)
SERPINF2Serpin family F member 2; Belongs to the serpin family. (491 aa)
ITIH4Inter-alpha-trypsin inhibitor heavy chain 4. (930 aa)
ENSPTRP00000089678annotation not available (488 aa)
ENSPTRP00000089475annotation not available (268 aa)
ENSPTRP00000088582annotation not available (66 aa)
SERPING1Serpin peptidase inhibitor, clade G (C1 inhibitor), member 1; Belongs to the serpin family. (496 aa)
MSNMSN isoform 1. (577 aa)
INTS11INTS11 isoform 7. (606 aa)
ENSPTRP00000086563annotation not available (245 aa)
CK820_G0055133IGHD isoform 2. (577 aa)
JCHAINJoining chain of multimeric IgA and IgM. (159 aa)
ACTG2ACTG2 isoform 7; Belongs to the actin family. (401 aa)
FGGFibrinogen gamma chain. (453 aa)
STOMSTOM isoform 3. (288 aa)
ENSPTRP00000082975annotation not available (212 aa)
LOC472599Heat shock cognate 71 kDa protein pseudogene. (400 aa)
LOC748740HSPA6 isoform 1; Belongs to the heat shock protein 70 family. (644 aa)
ENSPTRP00000081955annotation not available (66 aa)
DNPEPAspartyl aminopeptidase; Belongs to the peptidase M18 family. (493 aa)
TMPRSS13TMPRSS13 isoform 5; Belongs to the peptidase S1 family. (588 aa)
GRIPAP1GRIP1 associated protein 1. (828 aa)
HSPA2Heat shock 70kDa protein 2; Belongs to the heat shock protein 70 family. (642 aa)
ACTG1ACTG1 isoform 13. (375 aa)
LOC100615440Moesin pseudogene. (516 aa)
GCGC isoform 2. (504 aa)
PZPPZP alpha-2-macroglobulin like. (1482 aa)
EIF2AEukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. (591 aa)
ITIH2ITIH2 isoform 1. (992 aa)
SLC2A1Solute carrier family 2 (Facilitated glucose transporter), member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (492 aa)
LOC10061124614-3-3 protein zeta/delta pseudogene. (212 aa)
LOC743313LOW QUALITY PROTEIN: C4b-binding protein alpha chain-like. (589 aa)
HSPA8Heat shock protein family A (Hsp70) member 8; Belongs to the heat shock protein 70 family. (646 aa)
YWHAZTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide; Belongs to the 14-3-3 family. (245 aa)
ENSPTRP00000074124annotation not available (400 aa)
ENSPTRP00000072249annotation not available (396 aa)
LOC739666Syntenin-1-like. (289 aa)
ENSPTRP00000070878annotation not available (324 aa)
ENSPTRP00000070303annotation not available (117 aa)
ACSM1ACSM1 isoform 4. (501 aa)
LOC462577-2Complement C4-A. (1742 aa)
HPHP isoform 15. (92 aa)
ITIH1Inter-alpha-trypsin inhibitor heavy chain 1. (924 aa)
F13A1Coagulation factor XIII, A1 polypeptide. (811 aa)
KNG1KNG1 isoform 2. (644 aa)
LOC100616513Complement C4-A-like. (1750 aa)
LOC462577C4B isoform 1. (1750 aa)
SDCBPSyndecan binding protein. (324 aa)
ENSPTRP00000062406annotation not available (534 aa)
LOC460532LOW QUALITY PROTEIN: vitamin K-dependent protein S-like. (638 aa)
HPRHaptoglobin-related protein; Primate-specific plasma protein associated with apolipoprotein L-I (apoL-I)-containing high-density lipoprotein (HDL). Binds hemoglobin with high affinity and may contribute to the clearance of cell-free hemoglobin to allow hepatic recycling of heme iron. (348 aa)
ENSPTRP00000060619LOW QUALITY PROTEIN: heat shock 70 kDa protein 6. (632 aa)
LOC745166HSPA1A isoform 1; Belongs to the heat shock protein 70 family. (643 aa)
A2MAlpha-2-macroglobulin. (1474 aa)
PSMC5Proteasome (Prosome, macropain) 26S subunit, ATPase, 5; Belongs to the AAA ATPase family. (406 aa)
ALBALB isoform 2. (609 aa)
CK820_G0040173HP isoform 11. (376 aa)
C1SComplement component 1, s subcomponent; Belongs to the peptidase S1 family. (780 aa)
C1RComplement C1r subcomponent heavy chain; C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system; Belongs to the peptidase S1 family. (719 aa)
ZBTB38Zinc finger and BTB domain containing 38. (1195 aa)
CPN2Carboxypeptidase N subunit 2. (545 aa)
HSPA1LHSPA1L isoform 1; Belongs to the heat shock protein 70 family. (641 aa)
TFRCTransferrin receptor (P90, CD71). (760 aa)
CFHR1T0196413 isoform 1. (282 aa)
A1BGA1BG isoform 2. (496 aa)
ENGENG isoform 1. (658 aa)
GSNGSN isoform 3. (782 aa)
ORM2Alpha-1-acid glycoprotein; Functions as transport protein in the blood stream. Belongs to the calycin superfamily. Lipocalin family. (201 aa)
AMBPAlpha-1-microglobulin/bikunin precursor. (364 aa)
CLUClusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. (449 aa)
PON1PON1 isoform 1. (355 aa)
PLGPlasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (813 aa)
CLIC1Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (241 aa)
C9Complement C9. (559 aa)
FGAFibrinogen alpha chain. (866 aa)
FGBFibrinogen beta chain. (491 aa)
ANXA5Annexin A5; This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. (320 aa)
AFMAFM isoform 1. (599 aa)
HRGHistidine rich glycoprotein. (525 aa)
BCHECarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (643 aa)
CPCP isoform 1; Belongs to the multicopper oxidase family. (1069 aa)
PROS1Protein S (Alpha). (676 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
ZNF177Zinc finger protein 177. (481 aa)
ANGPTL4Angiopoietin-like 4. (406 aa)
C3Complement component 3. (465 aa)
LGALS3BPLectin, galactoside-binding, soluble, 3 binding protein. (585 aa)
ITGA2BITGA2B isoform 3; Belongs to the integrin alpha chain family. (1032 aa)
SLC4A1Anion exchange protein. (921 aa)
PFN1Profilin; Belongs to the profilin family. (140 aa)
CIB2Calcium and integrin binding family member 2. (187 aa)
SERPINA3Serpin peptidase inhibitor, clade A (Alpha-1 antiproteinase, antitrypsin), member 3; Belongs to the serpin family. (423 aa)
C1RLComplement component 1, r subcomponent-like; Belongs to the peptidase S1 family. (487 aa)
APOA4Apolipoprotein A4. (396 aa)
KDM4DLysine demethylase 4D. (523 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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