STRINGSTRING
MMRN2 MMRN2 SPRED1 SPRED1 MAP2K5 MAP2K5 HDAC5 HDAC5 RHOA RHOA PDCD10 PDCD10 MEOX2 MEOX2 KLF4 KLF4 NOTCH1 NOTCH1 TBXA2R TBXA2R THBS1 THBS1 DLL4 DLL4 STARD13 STARD13 ITGB1BP1 ITGB1BP1 CARD10 CARD10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MMRN2MMRN2 isoform 1. (949 aa)
SPRED1Sprouty-related, EVH1 domain containing 1. (444 aa)
MAP2K5Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (448 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1115 aa)
RHOARas homolog family member A. (193 aa)
PDCD10Programmed cell death 10. (212 aa)
MEOX2Mesenchyme homeobox 2. (302 aa)
KLF4Kruppel-like factor 4 (Gut). (479 aa)
NOTCH1NOTCH1 isoform 1. (2555 aa)
TBXA2RThromboxane A2 receptor; Belongs to the G-protein coupled receptor 1 family. (343 aa)
THBS1Thrombospondin 1. (1173 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (696 aa)
STARD13StAR-related lipid transfer (START) domain containing 13. (1113 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (200 aa)
CARD10Caspase recruitment domain family member 10. (1032 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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