Your Input: | |
| | CTNND1 | CTNND1 isoform 23. (975 aa) |
| | FZD1-2 | Frizzled class receptor 1. (580 aa) |
| | NPHP4 | NPHP4 isoform 5. (1426 aa) |
| | CDH2 | Cadherin 2, type 1, N-cadherin (Neuronal); Cadherins are calcium-dependent cell adhesion proteins. (914 aa) |
| | HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1. (1608 aa) |
| | DKK3 | Dickkopf WNT signaling pathway inhibitor 3. (413 aa) |
| | ENSPTRP00000089297 | annotation not available (265 aa) |
| | SOSTDC1-2 | Sclerostin domain containing 1. (206 aa) |
| | APC2 | APC2 isoform 1. (2301 aa) |
| | PRICKLE1 | PRICKLE1 isoform 11. (831 aa) |
| | FERMT1 | Fermitin family member 1. (677 aa) |
| | FZD1 | FZD1 isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (580 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | MDK | Midkine (Neurite growth-promoting factor 2). (143 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (544 aa) |
| | ENSPTRP00000083999 | annotation not available (92 aa) |
| | ENSPTRP00000083721 | annotation not available (394 aa) |
| | FRMD8 | FERM domain containing 8. (464 aa) |
| | LZTS2 | Leucine zipper putative tumor suppressor 2; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta- catenin. (669 aa) |
| | CYLD | CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (956 aa) |
| | MCC | Colorectal mutant cancer protein isoform X6. (1015 aa) |
| | EMD | EMD isoform 1. (254 aa) |
| | LRP4 | Low density lipoprotein receptor-related protein 4. (1906 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (481 aa) |
| | TCF7L2 | Transcription factor 7 like 2. (619 aa) |
| | STK3 | Serine/threonine kinase 3. (519 aa) |
| | CTNNBIP1 | Catenin, beta interacting protein 1. (81 aa) |
| | ANKRD6 | Ankyrin repeat domain 6. (727 aa) |
| | SCYL2 | SCYL2 isoform 1. (962 aa) |
| | PTPRO | Protein tyrosine phosphatase receptor type O. (1216 aa) |
| | CK820_G0051198 | TLE2 isoform 3. (113 aa) |
| | GLI1 | GLI family zinc finger 1. (1106 aa) |
| | LOC465674 | LOW QUALITY PROTEIN: putative FERM domain-containing protein FRMD8P1. (452 aa) |
| | G3BP1 | GTPase activating protein (SH3 domain) binding protein 1. (496 aa) |
| | TLE7 | TLE family member 7. (441 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa) |
| | BICC1 | Bicaudal C homolog 1. (1074 aa) |
| | AMFR | Autocrine motility factor receptor. (643 aa) |
| | ENSPTRP00000071968 | annotation not available (115 aa) |
| | TLE4 | TLE family member 4, transcriptional corepressor. (805 aa) |
| | DAB2 | Disabled homolog 2, mitogen-responsive phosphoprotein. (770 aa) |
| | PTPRU | Protein tyrosine phosphatase receptor type U. (1454 aa) |
| | TLE5 | AES isoform 1. (203 aa) |
| | CBY1 | Chibby family member 1, beta catenin antagonist. (169 aa) |
| | NKD2 | NKD inhibitor of WNT signaling pathway 2. (464 aa) |
| | ENSPTRP00000068492 | annotation not available (777 aa) |
| | JADE1 | Jade family PHD finger 1. (842 aa) |
| | SOSTDC1 | Sclerostin domain containing 1. (230 aa) |
| | ENSPTRP00000067619 | annotation not available (224 aa) |
| | SFRP5 | Secreted frizzled related protein 5. (317 aa) |
| | LOC748850 | HDAC2 isoform 9. (445 aa) |
| | CSNK1A1 | Casein kinase 1, alpha 1; Belongs to the protein kinase superfamily. (353 aa) |
| | RUVBL2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa) |
| | STK4 | Serine/threonine-protein kinase 4. (487 aa) |
| | MLLT3 | MLLT3 isoform 1. (570 aa) |
| | PFDN5-2 | Prefoldin subunit 5. (127 aa) |
| | TPBGL | Trophoblast glycoprotein like. (382 aa) |
| | CSNK1A1L | Casein kinase 1 alpha 1 like; Belongs to the protein kinase superfamily. (337 aa) |
| | DAB2IP | DAB2 interacting protein. (1189 aa) |
| | APOE | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (317 aa) |
| | AMER2 | APC membrane recruitment protein 2. (552 aa) |
| | NKD1 | NKD inhibitor of WNT signaling pathway 1. (470 aa) |
| | UBAC2 | Phosphoglycerate dehydrogenase-like protein 1. (344 aa) |
| | SFRP1 | Secreted frizzled-related protein 1. (314 aa) |
| | SHISA6 | Shisa family member 6. (551 aa) |
| | NOTUM | Notum, palmitoleoyl-protein carboxylesterase. (496 aa) |
| | TMEM170B | Transmembrane protein 170B. (132 aa) |
| | KREMEN1 | Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (450 aa) |
| | DACT3 | Dishevelled binding antagonist of beta catenin 3. (181 aa) |
| | AMER1 | APC membrane recruitment protein 1. (805 aa) |
| | SOX2 | SRY-box transcription factor 2. (319 aa) |
| | TLE2 | Transducin-like enhancer of split 2. (716 aa) |
| | TLE1 | Transducin-like enhancer of split 1. (814 aa) |
| | WWTR1 | WW domain containing transcription regulator 1. (400 aa) |
| | CTNNB1 | Catenin (Cadherin-associated protein), beta 1, 88kDa. (781 aa) |
| | FZD6 | Frizzled homolog 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (192 aa) |
| | AXIN1 | AXIN1 isoform 2. (859 aa) |
| | SOX10 | SRY-box transcription factor 10. (466 aa) |
| | OTUD5 | OTU deubiquitinase 5. (598 aa) |
| | NOTCH1 | NOTCH1 isoform 1. (2555 aa) |
| | INVS | INVS isoform 1. (1065 aa) |
| | CTHRC1 | Collagen triple helix repeat containing 1. (243 aa) |
| | TMEM64 | Transmembrane protein 64. (380 aa) |
| | SOX17 | SOX17 isoform 1. (416 aa) |
| | SNAI2 | Snail family transcriptional repressor 2. (268 aa) |
| | DKK4 | Dickkopf WNT signaling pathway inhibitor 4. (224 aa) |
| | CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa) |
| | IGFBP1 | IGFBP1 isoform 1. (281 aa) |
| | GLI3 | Transcriptional repressor GLI3R; Has a dual function as a transcriptional activator and a repressor of the sonic hedgehog (Shh) pathway, and plays a role in limb development. The full-length GLI3 form (GLI3FL) after phosphorylation and nuclear translocation, acts as an activator (GLI3A) while GLI3R, its C-terminally truncated form, acts as a repressor. A proper balance between the GLI3 activator and the repressor GLI3R, rather than the repressor gradient itself or the activator/repressor ratio gradient, specifies limb digit number and identity. In concert with TRPS1, plays a role in re [...] (1580 aa) |
| | SFRP4 | SFRP4 isoform 1. (368 aa) |
| | PRKN | E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa) |
| | LATS1 | LATS, large tumor suppressor, homolog 1. (1130 aa) |
| | TBX18 | T-box transcription factor 18. (607 aa) |
| | TPBG | Trophoblast glycoprotein. (420 aa) |
| | MAPK14 | Mitogen-activated protein kinase 14; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are a [...] (360 aa) |
| | NKX2-5 | NKX2-5 isoform 1. (325 aa) |
| | APC | Adenomatous polyposis coli protein isoform X10. (2844 aa) |
| | ISL1 | ISL LIM homeobox 1. (349 aa) |
| | SFRP2 | Secreted frizzled-related protein 2. (295 aa) |
| | TMEM131L | TMEM131L isoform 3. (1617 aa) |
| | DKK2 | Dickkopf WNT signaling pathway inhibitor 2. (259 aa) |
| | SHISA3 | Shisa family member 3. (238 aa) |
| | SIAH2 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (324 aa) |
| | PPP2R3A | PPP2R3A isoform 1. (1150 aa) |
| | LIMD1 | LIM domains containing 1. (676 aa) |
| | RBMS3 | RNA binding motif, single stranded interacting protein 3. (437 aa) |
| | RBX1 | Ring-box 1, E3 ubiquitin protein ligase. (108 aa) |
| | ZNRF3 | ZNRF3 isoform 1. (920 aa) |
| | BMP2 | Bone morphogenetic protein 2. (398 aa) |
| | FRZB | Frizzled-related protein. (325 aa) |
| | FUZ | Fuzzy planar cell polarity protein. (418 aa) |
| | DKKL1 | Dickkopf like acrosomal protein 1. (242 aa) |
| | GSK3A | Glycogen synthase kinase 3 alpha. (483 aa) |
| | TLE6 | TLE family member 6, subcortical maternal complex member. (572 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (307 aa) |
| | SLC9A3R1 | Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (358 aa) |
| | SOX9 | Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa) |
| | AXIN2 | AXIN2 isoform 1. (843 aa) |
| | NOG | Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa) |
| | SOST | SOST isoform 1. (213 aa) |
| | IGFBP4 | Insulin like growth factor binding protein 4. (258 aa) |
| | TMEM88 | Transmembrane protein 88. (159 aa) |
| | MESP1 | Mesoderm posterior bHLH transcription factor 1. (268 aa) |
| | TLE3 | TLE family member 3, transcriptional corepressor. (782 aa) |
| | CCDC88C | CCDC88C isoform 3. (2028 aa) |
| | DACT1 | Dishevelled binding antagonist of beta catenin 1. (836 aa) |
| | CHD8 | Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2589 aa) |
| | FOXO1 | FOXO1 isoform 1. (655 aa) |
| | LATS2 | Non-specific serine/threonine protein kinase. (1088 aa) |
| | CK820_G0016130 | SCYL2 isoform 5. (871 aa) |
| | PFDN5 | Prefoldin subunit 5. (154 aa) |
| | LMBR1L | Limb development membrane protein 1 like; Belongs to the LIMR family. (489 aa) |
| | FZD4 | FZD4 isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (540 aa) |
| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) |
| | DKK1 | Dickkopf-like protein 1. (289 aa) |
| | SOX13 | SRY (Sex determining region Y)-box 13. (622 aa) |
| | TNN | TNN isoform 1. (1299 aa) |
| | NPPA | Natriuretic peptide A. (153 aa) |
| | DRAXIN | Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (349 aa) |
| | MAD2L2 | MAD2 mitotic arrest deficient-like 2. (211 aa) |
