STRINGSTRING
CDCA8 CDCA8 PCID2-2 PCID2-2 XRCC3 XRCC3 AURKB AURKB NDC80 NDC80 DYNC1LI1 DYNC1LI1 MAD2L1 MAD2L1 TPR TPR MAD1L1 MAD1L1 BIRC5 BIRC5 INCENP INCENP AURKB-2 AURKB-2 ENSPTRP00000079401 ENSPTRP00000079401 GEN1 GEN1 PCID2 PCID2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CDCA8Cell division cycle associated 8. (280 aa)
PCID2-2PCI domain-containing protein 2. (399 aa)
XRCC3DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (348 aa)
AURKBAURKB isoform 1; Belongs to the protein kinase superfamily. (344 aa)
NDC80NDC80 homolog, kinetochore complex component. (642 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (523 aa)
MAD2L1MAD2 mitotic arrest deficient-like 1. (205 aa)
TPRTranslocated promoter region (To activated MET oncogene). (2363 aa)
MAD1L1MAD1 mitotic arrest deficient-like 1. (718 aa)
BIRC5Baculoviral IAP repeat containing 5. (165 aa)
INCENPInner centromere protein antigens 135/155kDa. (913 aa)
AURKB-2Aurora kinase B. (344 aa)
ENSPTRP00000079401annotation not available (162 aa)
GEN1GEN1 Holliday junction 5' flap endonuclease. (908 aa)
PCID2PCI domain containing 2. (398 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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