STRINGSTRING
DHRS3 DHRS3 KIF17 KIF17 GNAT2 GNAT2 ATP1A4 ATP1A4 KIFAP3 KIFAP3 PDC PDC RD3 RD3 OPN3 OPN3 SDCCAG8 SDCCAG8 STX3 STX3 ROM1 ROM1 SHANK2 SHANK2 PDE6H PDE6H CEP290 CEP290 GRK1 GRK1 CK820_G0025122 CK820_G0025122 RAB27A RAB27A CIB2 CIB2 IFT140 IFT140 RPGRIP1L RPGRIP1L GUCY2D GUCY2D RCVRN RCVRN USH1G USH1G BSG BSG C2AH2orf71 C2AH2orf71 CERKL CERKL INHA INHA SAG SAG IFT52 IFT52 CFAP410 CFAP410 MYRIP MYRIP GNAT1 GNAT1 CCDC66 CCDC66 IFT57 IFT57 IQCB1 IQCB1 IFT122 IFT122 RHO RHO GRK4 GRK4 LYAR LYAR PROM1 PROM1 WDR19 WDR19 CNGA1-2 CNGA1-2 PPEF2 PPEF2 RRH RRH BBS7 BBS7 MAP1B MAP1B VCAN VCAN CETN3 CETN3 PCDHB15 PCDHB15 PDE6A PDE6A GUCA1A GUCA1A GUCA1B GUCA1B PRPH2 PRPH2 TBCC TBCC PEX6 PEX6 LCA5 LCA5 MAGI2 MAGI2 GNGT1 GNGT1 NAPEPLD NAPEPLD OPN1SW OPN1SW KIAA1549 KIAA1549 RP1 RP1 CNGB3 CNGB3 CACNA1F CACNA1F ARR3 ARR3 GUCY2F GUCY2F CETN2 CETN2 GUCA1C GUCA1C MAK MAK NXNL1 NXNL1 SEPTIN2 SEPTIN2 CDHR1 CDHR1 CRB1 CRB1 OPN1LW OPN1LW USH1C USH1C GNAQ GNAQ TOPORS TOPORS CETN1 CETN1 GNAT3 GNAT3 BBS4 BBS4 USH2A USH2A TMEM237 TMEM237 ABCA4 ABCA4 RGS9BP RGS9BP CK820_G0043405 CK820_G0043405 GRK7 GRK7 TTC8 TTC8 GNB1 GNB1 WHRN WHRN CK820_G0051040 CK820_G0051040 OCRL OCRL PDE6B PDE6B PIP4K2A PIP4K2A CNGB1 CNGB1 FAM161A FAM161A RPGRIP1 RPGRIP1 NPHP1 NPHP1 GNA11 GNA11 ENSPTRP00000075783 ENSPTRP00000075783 SPTBN5 SPTBN5 MYO7A MYO7A MERTK MERTK PRCD PRCD ENSPTRP00000077377 ENSPTRP00000077377 IFT20 IFT20 TSGA10IP TSGA10IP OPN4 OPN4 PCDH15 PCDH15 RPGR RPGR CETN2-2 CETN2-2 PTGS1 PTGS1 ARL3 ARL3 PDE6G PDE6G HNF1A HNF1A ROM1-2 ROM1-2 EYS EYS CEP250 CEP250 PHLPP2 PHLPP2 CNGA1 CNGA1 SPATA7 SPATA7 RGR RGR RP1L1 RP1L1 TULP1 TULP1 NPHP4 NPHP4 IMPG1 IMPG1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DHRS3Dehydrogenase/reductase (SDR family) member 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
KIF17KIF17 isoform 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (929 aa)
GNAT2G protein subunit alpha transducin 2. (354 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1029 aa)
KIFAP3Kinesin-associated protein 3. (792 aa)
PDCPDC isoform 1. (246 aa)
RD3Retinal degeneration 3, GUCY2D regulator. (195 aa)
OPN3CHML isoform 2. (402 aa)
SDCCAG8Serologically defined colon cancer antigen 8. (713 aa)
STX3STX3 isoform 2; Belongs to the syntaxin family. (290 aa)
ROM1Retinal outer segment membrane protein 1. (351 aa)
SHANK2SH3 and multiple ankyrin repeat domains 2. (1849 aa)
PDE6HPhosphodiesterase 6H. (83 aa)
CEP290CEP290 isoform 5. (2454 aa)
GRK1G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (563 aa)
CK820_G0025122SLC24A4 isoform 1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (343 aa)
RAB27ARAB27A, member RAS oncogene family. (221 aa)
CIB2Calcium and integrin binding family member 2. (187 aa)
IFT140Intraflagellar transport 140 homolog. (1471 aa)
RPGRIP1LRPGRIP1L isoform 4. (1269 aa)
GUCY2DGuanylate cyclase. (1103 aa)
RCVRNRCVRN isoform 1. (200 aa)
USH1GUSH1 protein network component sans. (461 aa)
BSGBSG isoform 8. (383 aa)
C2AH2orf71C2orf71 isoform 1. (1289 aa)
CERKLCeramide kinase like. (558 aa)
INHAInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (366 aa)
SAGS-antigen visual arrestin. (405 aa)
IFT52Intraflagellar transport 52 homolog. (437 aa)
CFAP410Cilia and flagella associated protein 410. (376 aa)
MYRIPMYRIP isoform 1. (805 aa)
GNAT1G protein subunit alpha transducin 1. (350 aa)
CCDC66Coiled-coil domain containing 66. (949 aa)
IFT57Intraflagellar transport 57 homolog. (429 aa)
IQCB1IQ motif containing B1. (598 aa)
IFT122IFT122 isoform 10. (1286 aa)
RHORhodopsin. (348 aa)
GRK4G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (578 aa)
LYARLYAR isoform 2. (405 aa)
PROM1PROM1 isoform 12. (865 aa)
WDR19WD repeat domain 19. (1342 aa)
CNGA1-2Cyclic nucleotide gated channel subunit alpha 1. (759 aa)
PPEF2Serine/threonine-protein phosphatase with EF-hands. (753 aa)
RRHRetinal pigment epithelium-derived rhodopsin homolog; Belongs to the G-protein coupled receptor 1 family. (337 aa)
BBS7Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. (715 aa)
MAP1BMicrotubule associated protein 1B. (2468 aa)
VCANVCAN isoform 3. (3396 aa)
CETN3CETN3 isoform 3. (191 aa)
PCDHB15Protocadherin beta-15; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. (787 aa)
PDE6APhosphodiesterase. (876 aa)
GUCA1AGUCA1A isoform 1. (207 aa)
GUCA1BGuanylate cyclase activator 1B. (200 aa)
PRPH2PRPH2 isoform 1. (346 aa)
TBCCTubulin folding cofactor C. (377 aa)
PEX6PEX6 isoform 1. (980 aa)
LCA5Leber congenital amaurosis 5. (697 aa)
MAGI2Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1283 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
NAPEPLDN-acyl phosphatidylethanolamine phospholipase D. (393 aa)
OPN1SWShort-wave-sensitive opsin 1; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal (By similarity). Required for the maintenance of cone outer segment organization in the ventral retina, but not essential for the maintenance of functioning cone photoreceptors (By similarity). Involved in ensuring correct abundance and localization of retinal membrane proteins (By similarity). May increase spectral sensitivity in dim light (By similarity). (348 aa)
KIAA1549KIAA1549 isoform 2. (1950 aa)
RP1RP1 axonemal microtubule associated. (2156 aa)
CNGB3CNGB3 isoform 2. (809 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1984 aa)
ARR3ARR3 isoform 1. (388 aa)
GUCY2FGuanylate cyclase. (1108 aa)
CETN2Centrin 2. (176 aa)
GUCA1CGuanylate cyclase activator 1C. (209 aa)
MAKMale germ cell associated kinase. (648 aa)
NXNL1Nucleoredoxin like 1. (212 aa)
SEPTIN2SEPT2 isoform 11; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (396 aa)
CDHR1Cadherin related family member 1. (859 aa)
CRB1Crumbs cell polarity complex component 1. (1406 aa)
OPN1LWOPN1MW2 isoform 1. (364 aa)
USH1CUSH1C isoform 4. (899 aa)
GNAQGuanine nucleotide binding protein (G protein), q polypeptide. (359 aa)
TOPORSTopoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase. (1045 aa)
CETN1CETN1 isoform 1. (172 aa)
GNAT3G protein subunit alpha transducin 3. (354 aa)
BBS4Bardet-Biedl syndrome 4. (519 aa)
USH2AUSH2A isoform 2. (5202 aa)
TMEM237Amyotrophic lateral sclerosis 2 (Juvenile) chromosome region, candidate 4. (408 aa)
ABCA4ABCA4 isoform 2. (2282 aa)
RGS9BPRegulator of G protein signaling 9 binding protein. (235 aa)
CK820_G0043405RPGR isoform 4. (902 aa)
GRK7G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (553 aa)
TTC8Tetratricopeptide repeat domain 8. (531 aa)
GNB1Guanine nucleotide binding protein (G protein), beta polypeptide 1. (340 aa)
WHRNWHRN isoform 2. (907 aa)
CK820_G0051040EYS isoform 4. (318 aa)
OCRLOCRL inositol polyphosphate-5-phosphatase. (901 aa)
PDE6BPDE6B isoform 6. (747 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase, type II, alpha. (406 aa)
CNGB1Cyclic nucleotide gated channel subunit beta 1. (1251 aa)
FAM161AFAM161A isoform 2. (716 aa)
RPGRIP1RPGR interacting protein 1. (1287 aa)
NPHP1NPHP1 isoform 1. (729 aa)
GNA11Guanine nucleotide binding protein (G protein), alpha 11 (Gq class). (359 aa)
ENSPTRP00000075783annotation not available (149 aa)
SPTBN5LOW QUALITY PROTEIN: spectrin beta chain, non-erythrocytic 5. (3705 aa)
MYO7AMYO7A isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2222 aa)
MERTKMERTK isoform 1. (963 aa)
PRCDPhotoreceptor disc component. (54 aa)
ENSPTRP00000077377annotation not available (149 aa)
IFT20IFT20 isoform 5. (164 aa)
TSGA10IPTestis specific 10 interacting protein. (556 aa)
OPN4OPN4 isoform 3. (495 aa)
PCDH15Protocadherin related 15. (1954 aa)
RPGRRPGR isoform 3. (1020 aa)
CETN2-2Centrin, EF-hand protein, 2. (172 aa)
PTGS1Prostaglandin-endoperoxide synthase 1 (Prostaglandin G/H synthase and cyclooxygenase). (599 aa)
ARL3ADP-ribosylation factor-like 3; Belongs to the small GTPase superfamily. Arf family. (151 aa)
PDE6GPhosphodiesterase 6G. (137 aa)
HNF1AHNF1 homeobox A. (662 aa)
ROM1-2Retinal outer segment membrane protein 1. (351 aa)
EYSEYS isoform 1. (3144 aa)
CEP250CEP250 isoform 4. (2443 aa)
PHLPP2PHLPP2 isoform 2. (1358 aa)
CNGA1Cyclic nucleotide gated channel subunit alpha 1. (672 aa)
SPATA7Spermatogenesis associated 7. (599 aa)
RGRRGR isoform 4; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. (291 aa)
RP1L1RP1L1 isoform 1. (2257 aa)
TULP1Tubby-like protein; Belongs to the TUB family. (542 aa)
NPHP4NPHP4 isoform 5. (1426 aa)
IMPG1IMPG1 isoform 1. (800 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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