STRINGSTRING
ESD ESD SELENOW SELENOW ENSPTRP00000093174 ENSPTRP00000093174 GSTK1-2 GSTK1-2 ENSPTRP00000092300 ENSPTRP00000092300 PRDX4 PRDX4 PXDN PXDN HBA2 HBA2 ENSPTRP00000090441 ENSPTRP00000090441 ENSPTRP00000089965 ENSPTRP00000089965 UPK3BL1 UPK3BL1 GSTO2 GSTO2 ENSPTRP00000084468 ENSPTRP00000084468 MT1HL1 MT1HL1 SOD2 SOD2 PRXL2B PRXL2B ENSPTRP00000082718 ENSPTRP00000082718 AKR1A1 AKR1A1 PTGS1 PTGS1 TXNL1 TXNL1 ENSPTRP00000081633 ENSPTRP00000081633 GSTM3 GSTM3 MT1L MT1L ENSPTRP00000079953 ENSPTRP00000079953 ENSPTRP00000079686 ENSPTRP00000079686 SLC30A1 SLC30A1 PARK7 PARK7 HBQ1 HBQ1 RDH11 RDH11 SELENOW-2 SELENOW-2 TPO TPO SRXN1 SRXN1 LOC100615743 LOC100615743 ENSPTRP00000074383 ENSPTRP00000074383 GSTZ1 GSTZ1 ENSPTRP00000073959 ENSPTRP00000073959 GLRX GLRX GPX5 GPX5 GPX8 GPX8 SLC22A18 SLC22A18 AKR7A3 AKR7A3 ENSPTRP00000072249 ENSPTRP00000072249 LOC101058101 LOC101058101 ALDH1A1 ALDH1A1 TXNRD1 TXNRD1 ENSPTRP00000070902 ENSPTRP00000070902 ENSPTRP00000070073 ENSPTRP00000070073 LOC736283 LOC736283 ADH4 ADH4 SLC47A2 SLC47A2 SELENOF SELENOF MGST1 MGST1 GSTK1 GSTK1 ABCB6 ABCB6 HBA1 HBA1 GSTM3-2 GSTM3-2 HP HP ENSPTRP00000066724 ENSPTRP00000066724 ENSPTRP00000065779 ENSPTRP00000065779 CLIC2-2 CLIC2-2 DUOX1 DUOX1 SLC22A5 SLC22A5 OSCP1 OSCP1 MT1M MT1M NFE2L2 NFE2L2 ATP7A ATP7A ENSPTRP00000063234 ENSPTRP00000063234 ENSPTRP00000062913 ENSPTRP00000062913 GSTO1 GSTO1 MT1H MT1H ENSPTRP00000061305 ENSPTRP00000061305 SELENOT SELENOT SELENOS SELENOS MT1H-2 MT1H-2 PRDX6 PRDX6 HBG2 HBG2 SLC47A1 SLC47A1 TXNRD2 TXNRD2 ALB ALB AKR1B10 AKR1B10 CK820_G0040173 CK820_G0040173 HBD HBD APOE APOE DHRS12 DHRS12 MT1E MT1E UBIAD1 UBIAD1 GPX2 GPX2 GPX1 GPX1 GPX6 GPX6 IPCEF1 IPCEF1 TXNDC2 TXNDC2 RALBP1 RALBP1 PRXL2C PRXL2C GPX4 GPX4 HBG1 HBG1 GPX3 GPX3 GSTP1 GSTP1 CLIC2 CLIC2 MFSD11 MFSD11 PDZK1 PDZK1 HBM HBM SLC17A3 SLC17A3 GPX7 GPX7 PTGES PTGES AMBP AMBP TXN TXN FANCC FANCC TP53INP1 TP53INP1 PXDNL PXDNL GSR GSR NOS3 NOS3 ABCB1 ABCB1 SESN1 SESN1 GSTA1 GSTA1 PIM1 PIM1 APOM APOM LTC4S LTC4S MGST2 MGST2 ADH5 ADH5 ABCG2 ABCG2 MT2A MT2A SOD3 SOD3 TXNRD3 TXNRD3 SLC15A2 SLC15A2 LOC470264 LOC470264 SOD1 SOD1 FABP1 FABP1 PRDX2 PRDX2 CYGB CYGB MPO MPO LPO LPO EPX EPX TXNDC17 TXNDC17 NXN NXN NQO1 NQO1 MT1X MT1X MT1A MT1A LOC467981 LOC467981 MT1F MT1F MT3 MT3 MT4 MT4 HBZ HBZ ENSPTRP00000012856 ENSPTRP00000012856 DUOX2 DUOX2 RDH12 RDH12 ATP7B ATP7B ALOX5AP ALOX5AP MGST1-2 MGST1-2 APOA4 APOA4 CCS CCS PRDX5 PRDX5 CAT CAT HBE1 HBE1 HBB HBB PRDX3 PRDX3 PRXL2A PRXL2A MARC1 MARC1 MARC2 MARC2 SLC30A10 SLC30A10 PTGS2 PTGS2 MGST3 MGST3 S100A9 S100A9 GSTM1 GSTM1 PRDX1 PRDX1 SESN2 SESN2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ESDS-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (282 aa)
SELENOWSELENOW isoform 2. (88 aa)
ENSPTRP00000093174annotation not available (208 aa)
GSTK1-2Glutathione S-transferase kappa 1. (282 aa)
ENSPTRP00000092300annotation not available (252 aa)
PRDX4PRDX4 isoform 2. (271 aa)
PXDNPeroxidasin homolog. (1479 aa)
HBA2Pan troglodytes hemoglobin subunit alpha 2 (HBA2), mRNA. (145 aa)
ENSPTRP00000090441annotation not available (111 aa)
ENSPTRP00000089965annotation not available (106 aa)
UPK3BL1Uroplakin-3b-like protein 1 isoform X2. (263 aa)
GSTO2Glutathione S-transferase omega 2; Belongs to the GST superfamily. (243 aa)
ENSPTRP00000084468annotation not available (154 aa)
MT1HL1Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (61 aa)
SOD2Superoxide dismutase [Mn], mitochondrial; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (238 aa)
PRXL2BFAM213B isoform 6. (288 aa)
ENSPTRP00000082718annotation not available (235 aa)
AKR1A1Aldo-keto reductase family 1, member A1 (Aldehyde reductase). (324 aa)
PTGS1Prostaglandin-endoperoxide synthase 1 (Prostaglandin G/H synthase and cyclooxygenase). (599 aa)
TXNL1Thioredoxin-like 1. (292 aa)
ENSPTRP00000081633annotation not available (139 aa)
GSTM3Glutathione S-transferase mu 3. (225 aa)
MT1LMetallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (79 aa)
ENSPTRP00000079953annotation not available (70 aa)
ENSPTRP00000079686annotation not available (213 aa)
SLC30A1Solute carrier family 30 (Zinc transporter), member 1. (507 aa)
PARK7PARK7 isoform 1. (189 aa)
HBQ1Hemoglobin subunit theta 1; Belongs to the globin family. (142 aa)
RDH11Retinol dehydrogenase 11 (All-trans/9-cis/11-cis); Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa)
SELENOW-2Selenoprotein W. (92 aa)
TPOTPO isoform 5. (847 aa)
SRXN1Sulfiredoxin. (165 aa)
LOC100615743Peroxiredoxin-1-like. (171 aa)
ENSPTRP00000074383annotation not available (55 aa)
GSTZ1Glutathione S-transferase zeta 1; Belongs to the GST superfamily. (217 aa)
ENSPTRP00000073959annotation not available (76 aa)
GLRXGlutaredoxin (Thioltransferase). (106 aa)
GPX5Glutathione peroxidase 5. (211 aa)
GPX8Glutathione peroxidase; Belongs to the glutathione peroxidase family. (209 aa)
SLC22A18Solute carrier family 22, member 18. (424 aa)
AKR7A3Aldo-keto reductase family 7 member A3. (354 aa)
ENSPTRP00000072249annotation not available (396 aa)
LOC101058101Metallothionein 1/2. (52 aa)
ALDH1A1Aldehyde dehydrogenase 1 family, member A1; Belongs to the aldehyde dehydrogenase family. (532 aa)
TXNRD1TXNRD1 isoform 3. (648 aa)
ENSPTRP00000070902annotation not available (168 aa)
ENSPTRP00000070073annotation not available (155 aa)
LOC736283Glutathione peroxidase 1 pseudogene. (188 aa)
ADH4Alcohol dehydrogenase 4 (class II), pi polypeptide. (399 aa)
SLC47A2Multidrug and toxin extrusion protein; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. (602 aa)
SELENOFSELENOF isoform 6. (164 aa)
MGST1Microsomal glutathione S-transferase 1. (155 aa)
GSTK1Glutathione S-transferase kappa. (281 aa)
ABCB6ATP-binding cassette, sub-family B (MDR/TAP), member 6. (854 aa)
HBA1Hemoglobin subunit alpha; Involved in oxygen transport from the lung to the various peripheral tissues; Belongs to the globin family. (142 aa)
GSTM3-2Glutathione S-transferase. (225 aa)
HPHP isoform 15. (92 aa)
ENSPTRP00000066724annotation not available (166 aa)
ENSPTRP00000065779annotation not available (204 aa)
CLIC2-2Chloride intracellular channel 2. (247 aa)
DUOX1DUOX1 isoform 1. (1551 aa)
SLC22A5Solute carrier family 22 member 5. (581 aa)
OSCP1OSCP1 isoform 4. (377 aa)
MT1MMetallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (69 aa)
NFE2L2Nuclear factor (Erythroid-derived 2)-like 2. (605 aa)
ATP7AATPase, Cu++ transporting, alpha polypeptide. (1500 aa)
ENSPTRP00000063234annotation not available (365 aa)
ENSPTRP00000062913annotation not available (169 aa)
GSTO1Glutathione S-transferase omega 1. (241 aa)
MT1HMetallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (85 aa)
ENSPTRP00000061305annotation not available (112 aa)
SELENOTSelenoprotein T; Belongs to the SelWTH family. Selenoprotein T subfamily. (189 aa)
SELENOSSELENOS isoform 5. (218 aa)
MT1H-2Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (61 aa)
PRDX6PRDX6 isoform 1. (224 aa)
HBG2Hemoglobin subunit gamma-2; Gamma chains make up the fetal hemoglobin F, in combination with alpha chains. (147 aa)
SLC47A1Multidrug and toxin extrusion protein; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. (586 aa)
TXNRD2TXNRD2 isoform 6. (517 aa)
ALBALB isoform 2. (609 aa)
AKR1B10AKR1B10 isoform 1. (316 aa)
CK820_G0040173HP isoform 11. (376 aa)
HBDHemoglobin subunit delta; Belongs to the globin family. (147 aa)
APOEApolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (317 aa)
DHRS12Dehydrogenase/reductase 12. (317 aa)
MT1EMT1E isoform 3; Belongs to the metallothionein superfamily. Type 1 family. (126 aa)
UBIAD1UbiA prenyltransferase domain containing 1. (338 aa)
GPX2GPX2 isoform 4. (150 aa)
GPX1Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown. (200 aa)
GPX6Glutathione peroxidase 6 precursor. (220 aa)
IPCEF1Interaction protein for cytohesin exchange factors 1. (438 aa)
TXNDC2TXNDC2 isoform 2. (520 aa)
RALBP1RalA binding protein 1. (655 aa)
PRXL2CAAED1 isoform 2. (226 aa)
GPX4Glutathione peroxidase; Belongs to the glutathione peroxidase family. (233 aa)
HBG1Hemoglobin subunit gamma-1; Gamma chains make up the fetal hemoglobin F, in combination with alpha chains. (147 aa)
GPX3GPX3 isoform 3. (225 aa)
GSTP1Glutathione S-transferase pi 1; Belongs to the GST superfamily. (210 aa)
CLIC2Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (247 aa)
MFSD11Major facilitator superfamily domain containing 11. (449 aa)
PDZK1PDZK1 isoform 1. (519 aa)
HBMHemoglobin subunit mu; Belongs to the globin family. (141 aa)
SLC17A3Solute carrier family 17 member 3. (498 aa)
GPX7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (187 aa)
PTGESProstaglandin E synthase. (152 aa)
AMBPAlpha-1-microglobulin/bikunin precursor. (364 aa)
TXNThioredoxin; Belongs to the thioredoxin family. (105 aa)
FANCCFanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. (558 aa)
TP53INP1TP53INP1 isoform 1. (240 aa)
PXDNLPXDNL isoform 2. (1463 aa)
GSRGlutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (522 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1203 aa)
ABCB1ATP binding cassette subfamily B member 1. (1280 aa)
SESN1SESN1 isoform 1. (551 aa)
GSTA1Glutathione S-transferase. (222 aa)
PIM1Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (535 aa)
APOMApolipoprotein M. (188 aa)
LTC4SLeukotriene C4 synthase. (150 aa)
MGST2Microsomal glutathione S-transferase 2. (147 aa)
ADH5S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (383 aa)
ABCG2ATP-binding cassette, sub-family G (WHITE), member 2. (655 aa)
MT2AMetallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (61 aa)
SOD3Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (240 aa)
TXNRD3TXNRD3 isoform 1. (642 aa)
SLC15A2Solute carrier family 15 member 2. (729 aa)
LOC470264Glutathione S-transferase theta 1; Belongs to the GST superfamily. (240 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
FABP1Fatty acid binding protein 1. (127 aa)
PRDX2PRDX2 isoform 1. (198 aa)
CYGBCYGB isoform 1; Belongs to the globin family. (190 aa)
MPOMyeloperoxidase. (745 aa)
LPOLPO isoform 1. (712 aa)
EPXEosinophil peroxidase. (715 aa)
TXNDC17Thioredoxin domain containing 17. (123 aa)
NXNNXN isoform 1. (435 aa)
NQO1NAD(P)H quinone dehydrogenase 1. (274 aa)
MT1XMetallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (61 aa)
MT1AMetallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (61 aa)
LOC467981Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (61 aa)
MT1FMetallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (61 aa)
MT3MT3 isoform 5; Belongs to the metallothionein superfamily. Type 1 family. (113 aa)
MT4Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (62 aa)
HBZHemoglobin subunit zeta; The zeta chain is an alpha-type chain of mammalian embryonic hemoglobin; Belongs to the globin family. (142 aa)
ENSPTRP00000012856annotation not available (109 aa)
DUOX2DUOX2 isoform 1. (1548 aa)
RDH12Retinol dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (316 aa)
ATP7BATPase copper transporting beta. (1465 aa)
ALOX5APArachidonate 5-lipoxygenase activating protein. (218 aa)
MGST1-2Microsomal glutathione S-transferase 1. (155 aa)
APOA4Apolipoprotein A4. (396 aa)
CCSCopper chaperone for superoxide dismutase. (274 aa)
PRDX5Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (214 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
HBE1Hemoglobin subunit epsilon; The epsilon chain is a beta-type chain of early mammalian embryonic hemoglobin. (147 aa)
HBBHemoglobin subunit beta; Involved in oxygen transport from the lung to the various peripheral tissues. (147 aa)
PRDX3PRDX3 isoform 1. (256 aa)
PRXL2AChromosome 10 open reading frame 58. (229 aa)
MARC1MOCO sulfurase C-terminal domain containing 1. (337 aa)
MARC2MARC2 isoform 1. (335 aa)
SLC30A10Solute carrier family 30 member 10. (485 aa)
PTGS2Prostaglandin-endoperoxide synthase 2 (Prostaglandin G/H synthase and cyclooxygenase). (604 aa)
MGST3Microsomal glutathione S-transferase 3. (165 aa)
S100A9Protein S100; Belongs to the S-100 family. (114 aa)
GSTM1GSTM1 isoform 3; Belongs to the GST superfamily. (218 aa)
PRDX1PRDX1 isoform 1. (199 aa)
SESN2SESN2 isoform 1. (480 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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