STRINGSTRING
ENSPTRP00000092784 ENSPTRP00000092784 ENSPTRP00000090392 ENSPTRP00000090392 FGF12 FGF12 SUMO1 SUMO1 CAMK2D CAMK2D HCN2 HCN2 CACNB3 CACNB3 GJA5 GJA5 ENSPTRP00000085903 ENSPTRP00000085903 SUMO1-3 SUMO1-3 ENSPTRP00000085085 ENSPTRP00000085085 ADRA1A ADRA1A SUMO1-2 SUMO1-2 CALM1 CALM1 CK820_G0013720 CK820_G0013720 TMEM130 TMEM130 CD36 CD36 ENSPTRP00000072925 ENSPTRP00000072925 CACNA2D1 CACNA2D1 SCN5A SCN5A FGF13 FGF13 SLC9A1 SLC9A1 DLG1 DLG1 ENSPTRP00000066578 ENSPTRP00000066578 KCNAB2 KCNAB2 ENSPTRP00000065655 ENSPTRP00000065655 AKAP9-2 AKAP9-2 RYR2 RYR2 FLNA FLNA LOC100612404 LOC100612404 CK820_G0042363 CK820_G0042363 KCNE3 KCNE3 GPR35 GPR35 NPS NPS RNF207 RNF207 GBA GBA AKAP9 AKAP9 MTNR1B MTNR1B ANK2 ANK2 CNR2 CNR2 NOS1AP NOS1AP FMR1 FMR1 CAV1 CAV1 TBX18 TBX18 DSP DSP TMEM161B TMEM161B HCN1 HCN1 CAV3 CAV3 CXADR CXADR CK820_G0037244 CK820_G0037244 KCNB1 KCNB1 SCN9A SCN9A BIN1 BIN1 TACR1 TACR1 TRPM4 TRPM4 ATP2A2 ATP2A2 HCN4 HCN4 RANGRF RANGRF JUP JUP KCNJ2 KCNJ2 DSC2 DSC2 CHRNB2 CHRNB2 DSG2 DSG2 HCN3 HCN3 CTNNA3 CTNNA3 CACNA1C CACNA1C PKP2 PKP2 PAWR PAWR ENSPTRP00000093588 ENSPTRP00000093588 SLC8A2 SLC8A2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPTRP00000092784annotation not available (75 aa)
ENSPTRP00000090392annotation not available (93 aa)
FGF12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
SUMO1SUMO1 isoform 3. (146 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (446 aa)
HCN2Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (775 aa)
CACNB3Calcium channel, voltage-dependent, beta 3 subunit. (487 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
ENSPTRP00000085903annotation not available (98 aa)
SUMO1-3Small ubiquitin-related modifier. (98 aa)
ENSPTRP00000085085annotation not available (84 aa)
ADRA1AAdrenoceptor alpha 1A. (495 aa)
SUMO1-2Small ubiquitin-related modifier. (82 aa)
CALM1CALM1 isoform 3; Belongs to the calmodulin family. (150 aa)
CK820_G0013720HCN2 isoform 1. (847 aa)
TMEM130Transmembrane protein 130. (435 aa)
CD36CD36 molecule (Thrombospondin receptor); Belongs to the CD36 family. (472 aa)
ENSPTRP00000072925annotation not available (372 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1103 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2016 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (926 aa)
ENSPTRP00000066578annotation not available (310 aa)
KCNAB2Potassium voltage-gated channel subfamily A regulatory beta subunit 2. (415 aa)
ENSPTRP00000065655annotation not available (349 aa)
AKAP9-2A-kinase anchoring protein 9. (3896 aa)
RYR2RYR2 isoform 1. (4941 aa)
FLNAFLNA isoform 8. (2711 aa)
LOC100612404Glucosylceramidase-like. (495 aa)
CK820_G0042363TRPM4 isoform 1. (1251 aa)
KCNE3Potassium voltage-gated channel subfamily E regulatory subunit 3. (103 aa)
GPR35G protein-coupled receptor 35; Belongs to the G-protein coupled receptor 1 family. (340 aa)
NPSNeuropeptide S. (89 aa)
RNF207Ring finger protein 207. (634 aa)
GBALysosomal acid glucosylceramidase; Glucosylceramidase that catalyzes, within the lysosomal compartment, the hydrolysis of glucosylceramide/GlcCer into free ceramide and glucose. Thereby, plays a central role in the degradation of complex lipids and the turnover of cellular membranes. Through the production of ceramides, participates to the PKC-activated salvage pathway of ceramide formation. Also plays a role in cholesterol metabolism. May either catalyze the glucosylation of cholesterol, through a transglucosylation reaction that transfers glucose from glucosylceramide to cholesterol. [...] (536 aa)
AKAP9A kinase (PRKA) anchor protein (Yotiao) 9. (3908 aa)
MTNR1BMelatonin receptor 1B; Belongs to the G-protein coupled receptor 1 family. (362 aa)
ANK2ANK2 isoform 1. (3957 aa)
CNR2Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. (360 aa)
NOS1APNitric oxide synthase 1 adaptor protein. (506 aa)
FMR1Fragile X mental retardation 1. (632 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
TBX18T-box transcription factor 18. (607 aa)
DSPDSP isoform 1. (2871 aa)
TMEM161BTransmembrane protein 161B. (502 aa)
HCN1HCN1 isoform 1. (886 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
CXADRCXADR Ig-like cell adhesion molecule. (365 aa)
CK820_G0037244NTSR1 isoform 1; Belongs to the G-protein coupled receptor 1 family. (350 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa)
SCN9ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1988 aa)
BIN1Bridging integrator 1. (597 aa)
TACR1Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (407 aa)
TRPM4Transient receptor potential cation channel, subfamily M, member 4. (1306 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
HCN4Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1203 aa)
RANGRFRAN guanine nucleotide release factor. (186 aa)
JUPJunction plakoglobin. (745 aa)
KCNJ2Potassium inwardly-rectifying channel, subfamily J, member 2. (427 aa)
DSC2DSC2 isoform 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (901 aa)
CHRNB2CHRNB2 isoform 2. (502 aa)
DSG2DSG2 isoform 1. (1118 aa)
HCN3Hyperpolarization activated cyclic nucleotide gated potassium channel 3. (774 aa)
CTNNA3CTNNA3 isoform 1. (895 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa)
PKP2PKP2 isoform 1. (837 aa)
PAWRPRKC, apoptosis, WT1, regulator. (340 aa)
ENSPTRP00000093588annotation not available (361 aa)
SLC8A2Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (921 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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