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CK820_G0042363 CK820_G0042363 KCNJ5 KCNJ5 RYR1 RYR1 ENSPTRP00000091918 ENSPTRP00000091918 GRIA1 GRIA1 ENSPTRP00000091352 ENSPTRP00000091352 RYR3 RYR3 KCNJ10 KCNJ10 CK820_G0030361 CK820_G0030361 GRIK3 GRIK3 CNGA1 CNGA1 CHRNA4 CHRNA4 HCN2 HCN2 KCNH6 KCNH6 KCNN1 KCNN1 CK820_G0056661 CK820_G0056661 ENSPTRP00000086934 ENSPTRP00000086934 KCNK1 KCNK1 GRIK1 GRIK1 ENSPTRP00000085296 ENSPTRP00000085296 GRIA4 GRIA4 ASIC1 ASIC1 P2RX2 P2RX2 HTR3A HTR3A ASIC3 ASIC3 CNGA3 CNGA3 KCNJ12 KCNJ12 CK820_G0013720 CK820_G0013720 CHRNA3 CHRNA3 CNGA2-2 CNGA2-2 GRIK4 GRIK4 GRIA3 GRIA3 TRPM8 TRPM8 ENSPTRP00000074534 ENSPTRP00000074534 KCNJ4 KCNJ4 CNGB1 CNGB1 GRIN2C GRIN2C CK820_G0010776 CK820_G0010776 ENSPTRP00000068927 ENSPTRP00000068927 TRPM2 TRPM2 RYR2 RYR2 GRIN2D GRIN2D SCNN1A SCNN1A PEX5L PEX5L KCNJ15 KCNJ15 KCNJ1 KCNJ1 TPCN2 TPCN2 TMEM177 TMEM177 P2RX3 P2RX3 CK820_G0015936 CK820_G0015936 GRIN2A GRIN2A CHRNB3 CHRNB3 SCNN1D SCNN1D KCNE2 KCNE2 CFAP299 CFAP299 P2RX5 P2RX5 MCOLN2 MCOLN2 P2RX7 P2RX7 CNGA4 CNGA4 KCNJ11 KCNJ11 ABCC8 ABCC8 KCNH2 KCNH2 TRPA1 TRPA1 CHRNG CHRNG TRPM5 TRPM5 GRIN1 GRIN1 KCNJ13 KCNJ13 GRIN3A GRIN3A KCNN3 KCNN3 CNGA2 CNGA2 CNGB3 CNGB3 CHRNA6 CHRNA6 CHRNA2 CHRNA2 PTK2B PTK2B AQP1 AQP1 GRIK2 GRIK2 ITPR3 ITPR3 KCNN2 KCNN2 HCN1 HCN1 GRIA2 GRIA2 ASIC5 ASIC5 PKD2 PKD2 CNGA1-2 CNGA1-2 CHRNA9 CHRNA9 HTR3E HTR3E HTR3C HTR3C HTR3D HTR3D CCDC51 CCDC51 ITPR1 ITPR1 ITPR2 ITPR2 P2RX6 P2RX6 CHRND CHRND ASIC4 ASIC4 CHRNA1 CHRNA1 KCNH7 KCNH7 KCNJ3 KCNJ3 TRPM4 TRPM4 KCNJ14 KCNJ14 GRIK5 GRIK5 KCNK6 KCNK6 MCOLN1 MCOLN1 KCNJ2 KCNJ2 KCNJ16 KCNJ16 ASIC2 ASIC2 CHRNB1 CHRNB1 CHRNE CHRNE P2RX1 P2RX1 TRPV1 TRPV1 SCNN1B SCNN1B SCNN1G SCNN1G CHRNB4 CHRNB4 CHRNA5 CHRNA5 HCN4 HCN4 CHRNA7 CHRNA7 RASA3 RASA3 P2RX4 P2RX4 TPCN1 TPCN1 KCNJ8 KCNJ8 GRIN2B GRIN2B KCNJ6 KCNJ6 HTR3B HTR3B CHRNA10 CHRNA10 KCNJ9 KCNJ9 CHRNB2 CHRNB2 KCNA10 KCNA10 MCOLN3 MCOLN3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CK820_G0042363TRPM4 isoform 1. (1251 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (419 aa)
RYR1RYR1 isoform 3. (5037 aa)
ENSPTRP00000091918annotation not available (454 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (916 aa)
ENSPTRP00000091352annotation not available (87 aa)
RYR3Ryanodine receptor 3. (4873 aa)
KCNJ10KCNJ10 isoform 1. (207 aa)
CK820_G0030361RYR1 isoform 5. (4901 aa)
GRIK3Glutamate ionotropic receptor kainate type subunit 3. (919 aa)
CNGA1Cyclic nucleotide gated channel subunit alpha 1. (672 aa)
CHRNA4Neuronal acetylcholine receptor subunit alpha-4; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions. (640 aa)
HCN2Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (775 aa)
KCNH6Potassium voltage-gated channel subfamily H member 6. (994 aa)
KCNN1Potassium calcium-activated channel subfamily N member 1. (543 aa)
CK820_G0056661KCNJ18 isoform 1. (433 aa)
ENSPTRP00000086934annotation not available (467 aa)
KCNK1Potassium channel subfamily K member. (337 aa)
GRIK1Glutamate ionotropic receptor kainate type subunit 1. (949 aa)
ENSPTRP00000085296Uncharacterized protein LOC107966511 isoform X1. (87 aa)
GRIA4Glutamate ionotropic receptor AMPA type subunit 4. (902 aa)
ASIC1ASIC1 isoform 4; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (562 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (497 aa)
HTR3A5-hydroxytryptamine receptor 3A; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (516 aa)
ASIC3Acid sensing ion channel subunit 3; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (549 aa)
CNGA3Cyclic nucleotide gated channel subunit alpha 3. (698 aa)
KCNJ12Potassium inwardly-rectifying channel, subfamily J, member 12. (433 aa)
CK820_G0013720HCN2 isoform 1. (847 aa)
CHRNA3Cholinergic receptor nicotinic alpha 3 subunit. (503 aa)
CNGA2-2Cyclic nucleotide gated channel subunit alpha 2. (664 aa)
GRIK4Glutamate receptor ionotropic, kainate 4; Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists (By similarity). (959 aa)
GRIA3Glutamate ionotropic receptor AMPA type subunit 3. (894 aa)
TRPM8TRPM8 isoform 2. (1104 aa)
ENSPTRP00000074534annotation not available (441 aa)
KCNJ4Potassium voltage-gated channel subfamily J member 4. (445 aa)
CNGB1Cyclic nucleotide gated channel subunit beta 1. (1251 aa)
GRIN2CGRIN2C isoform 4. (1240 aa)
CK820_G0010776TRPM8 isoform 5. (1112 aa)
ENSPTRP00000068927annotation not available (480 aa)
TRPM2TRPM2 isoform 4. (1393 aa)
RYR2RYR2 isoform 1. (4941 aa)
GRIN2DGRIN2D isoform 1. (1265 aa)
SCNN1AAmiloride-sensitive sodium channel subunit alpha; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and eccrine sweat glands. Also plays a role in taste perception. (692 aa)
PEX5LPeroxisomal biogenesis factor 5 like. (650 aa)
KCNJ15Potassium inwardly-rectifying channel, subfamily J, member 15. (375 aa)
KCNJ1Potassium voltage-gated channel subfamily J member 1. (420 aa)
TPCN2Two pore segment channel 2. (752 aa)
TMEM177TMEM177 isoform 1. (108 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (397 aa)
CK820_G0015936C12orf76 isoform 1. (107 aa)
GRIN2AGlutamate receptor ionotropic, NMDA 2A; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition; channels containing GRIN1 and GRIN2A have higher sensitivity to glutamate and faster kineti [...] (1471 aa)
CHRNB3Neuronal acetylcholine receptor subunit beta-3; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. (458 aa)
SCNN1DAmiloride-sensitive sodium channel subunit delta; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception. (802 aa)
KCNE2KCNE2 isoform 1. (123 aa)
CFAP299Cilia and flagella associated protein 299. (250 aa)
P2RX5P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (431 aa)
MCOLN2MCOLN2 isoform 1. (566 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
CNGA4Cyclic nucleotide gated channel subunit alpha 4. (575 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (390 aa)
ABCC8ABCC8 isoform 2. (1582 aa)
KCNH2Potassium voltage-gated channel subfamily H member 2. (1159 aa)
TRPA1Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1119 aa)
CHRNGCholinergic receptor nicotinic gamma subunit. (517 aa)
TRPM5Transient receptor potential cation channel subfamily M member 5. (1172 aa)
GRIN1Glutamate receptor, ionotropic, N-methyl D-aspartate 1. (845 aa)
KCNJ13Potassium voltage-gated channel subfamily J member 13. (360 aa)
GRIN3AGRIN3A isoform 1. (1115 aa)
KCNN3KCNN3 isoform 2. (756 aa)
CNGA2Cyclic nucleotide gated channel subunit alpha 2. (664 aa)
CNGB3CNGB3 isoform 2. (809 aa)
CHRNA6Neuronal acetylcholine receptor subunit alpha-6; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. (494 aa)
CHRNA2Neuronal acetylcholine receptor subunit alpha-2; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. (529 aa)
PTK2BPTK2B protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
AQP1Aquaporin-1 isoform X2. (269 aa)
GRIK2Glutamate ionotropic receptor kainate type subunit 2. (908 aa)
ITPR3ITPR3 isoform 1. (2677 aa)
KCNN2Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2. (843 aa)
HCN1HCN1 isoform 1. (886 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
ASIC5Acid sensing ion channel subunit family member 5; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (505 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (968 aa)
CNGA1-2Cyclic nucleotide gated channel subunit alpha 1. (759 aa)
CHRNA9Cholinergic receptor nicotinic alpha 9 subunit. (479 aa)
HTR3E5-hydroxytryptamine receptor 3E; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (482 aa)
HTR3CHTR3C isoform 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (447 aa)
HTR3DHTR3D isoform 3. (233 aa)
CCDC51Coiled-coil domain containing 51. (411 aa)
ITPR1ITPR1 isoform 3. (2700 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor, type 2. (2727 aa)
P2RX6P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (441 aa)
CHRNDCholinergic receptor nicotinic delta subunit. (517 aa)
ASIC4Acid sensing ion channel subunit family member 4; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (666 aa)
CHRNA1Cholinergic receptor, nicotinic, alpha 1 (Muscle). (482 aa)
KCNH7Potassium voltage-gated channel subfamily H member 7. (1196 aa)
KCNJ3Potassium voltage-gated channel subfamily J member 3. (501 aa)
TRPM4Transient receptor potential cation channel, subfamily M, member 4. (1306 aa)
KCNJ14Potassium voltage-gated channel subfamily J member 14. (436 aa)
GRIK5GRIK5 isoform 1. (980 aa)
KCNK6Potassium channel subfamily K member. (313 aa)
MCOLN1MCOLN1 isoform 1. (601 aa)
KCNJ2Potassium inwardly-rectifying channel, subfamily J, member 2. (427 aa)
KCNJ16Potassium voltage-gated channel subfamily J member 16. (457 aa)
ASIC2Acid sensing ion channel subunit 2; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (563 aa)
CHRNB1Cholinergic receptor, nicotinic, beta 1 (Muscle). (501 aa)
CHRNECholinergic receptor nicotinic epsilon subunit. (493 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (850 aa)
SCNN1BAmiloride-sensitive sodium channel subunit beta; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception; Belongs to the amiloride-sensit [...] (685 aa)
SCNN1GAmiloride-sensitive sodium channel subunit gamma; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception. (649 aa)
CHRNB4Cholinergic receptor nicotinic beta 4 subunit. (498 aa)
CHRNA5Neuronal acetylcholine receptor subunit alpha-5; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. (468 aa)
HCN4Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1203 aa)
CHRNA7CHRNA7 isoform 7. (511 aa)
RASA3RAS p21 protein activator 3. (740 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (346 aa)
TPCN1TPCN1 isoform 2. (888 aa)
KCNJ8Potassium inwardly-rectifying channel, subfamily J, member 8. (424 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
KCNJ6KCNJ6 isoform 1. (323 aa)
HTR3B5-hydroxytryptamine receptor 3B; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (441 aa)
CHRNA10Cholinergic receptor nicotinic alpha 10 subunit. (450 aa)
KCNJ9Potassium voltage-gated channel subfamily J member 9. (393 aa)
CHRNB2CHRNB2 isoform 2. (502 aa)
KCNA10Potassium voltage-gated channel subfamily A member 10; Belongs to the potassium channel family. (511 aa)
MCOLN3MCOLN3 isoform 1. (553 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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