Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATM | ATR | ENSPTRP00000054216 | ENSPTRP00000051017 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Ataxia telangiectasia and Rad3 related; Belongs to the PI3/PI4-kinase family. | 0.995 |
| ATM | EP300 | ENSPTRP00000054216 | ENSPTRP00000024841 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | E1A binding protein p300. | 0.732 |
| ATM | GSK3B | ENSPTRP00000054216 | ENSPTRP00000081705 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. | 0.465 |
| ATM | MTOR | ENSPTRP00000054216 | ENSPTRP00000000280 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. | 0.531 |
| ATM | SIRT1 | ENSPTRP00000054216 | ENSPTRP00000004394 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | SIRT1 isoform 2. | 0.620 |
| ATM | SIRT1-2 | ENSPTRP00000054216 | ENSPTRP00000093057 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Sirtuin 1. | 0.620 |
| ATR | ATM | ENSPTRP00000051017 | ENSPTRP00000054216 | Ataxia telangiectasia and Rad3 related; Belongs to the PI3/PI4-kinase family. | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | 0.995 |
| CREBBP | EP300 | ENSPTRP00000074980 | ENSPTRP00000024841 | CREB binding protein. | E1A binding protein p300. | 0.999 |
| CREBBP | HSF1 | ENSPTRP00000074980 | ENSPTRP00000087591 | CREB binding protein. | Heat shock transcription factor 1. | 0.470 |
| CREBBP | SIRT1 | ENSPTRP00000074980 | ENSPTRP00000004394 | CREB binding protein. | SIRT1 isoform 2. | 0.565 |
| CREBBP | SIRT1-2 | ENSPTRP00000074980 | ENSPTRP00000093057 | CREB binding protein. | Sirtuin 1. | 0.565 |
| DNAJB1 | DNAJB6 | ENSPTRP00000018078 | ENSPTRP00000074825 | DnaJ heat shock protein family (Hsp40) member B1. | DnaJ heat shock protein family (Hsp40) member B6. | 0.448 |
| DNAJB1 | DNAJC2 | ENSPTRP00000018078 | ENSPTRP00000047719 | DnaJ heat shock protein family (Hsp40) member B1. | DnaJ heat shock protein family (Hsp40) member C2. | 0.604 |
| DNAJB1 | DNAJC7 | ENSPTRP00000018078 | ENSPTRP00000015651 | DnaJ heat shock protein family (Hsp40) member B1. | DnaJ heat shock protein family (Hsp40) member C7. | 0.563 |
| DNAJB1 | HSF1 | ENSPTRP00000018078 | ENSPTRP00000087591 | DnaJ heat shock protein family (Hsp40) member B1. | Heat shock transcription factor 1. | 0.678 |
| DNAJB1 | SIRT1 | ENSPTRP00000018078 | ENSPTRP00000004394 | DnaJ heat shock protein family (Hsp40) member B1. | SIRT1 isoform 2. | 0.550 |
| DNAJB1 | SIRT1-2 | ENSPTRP00000018078 | ENSPTRP00000093057 | DnaJ heat shock protein family (Hsp40) member B1. | Sirtuin 1. | 0.550 |
| DNAJB6 | DNAJB1 | ENSPTRP00000074825 | ENSPTRP00000018078 | DnaJ heat shock protein family (Hsp40) member B6. | DnaJ heat shock protein family (Hsp40) member B1. | 0.448 |
| DNAJC2 | DNAJB1 | ENSPTRP00000047719 | ENSPTRP00000018078 | DnaJ heat shock protein family (Hsp40) member C2. | DnaJ heat shock protein family (Hsp40) member B1. | 0.604 |
| DNAJC7 | DNAJB1 | ENSPTRP00000015651 | ENSPTRP00000018078 | DnaJ heat shock protein family (Hsp40) member C7. | DnaJ heat shock protein family (Hsp40) member B1. | 0.563 |
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