STRINGSTRING
ENSPTRP00000085680 ENSPTRP00000085680 SUMO1-3 SUMO1-3 ENSPTRP00000085903 ENSPTRP00000085903 SLN SLN CACNB1 CACNB1 SELENON SELENON CACNB3 CACNB3 CAMK2D CAMK2D ENSPTRP00000088766 ENSPTRP00000088766 SUMO1 SUMO1 ENSPTRP00000090392 ENSPTRP00000090392 ENSPTRP00000090501 ENSPTRP00000090501 STAC2 STAC2 NOS1 NOS1 CK820_G0029100 CK820_G0029100 R3HDM2 R3HDM2 NPPA NPPA HPCA HPCA CASQ2 CASQ2 CASQ1 CASQ1 ATP1B1 ATP1B1 PPP3CA PPP3CA PDE4D PDE4D SLC9A1 SLC9A1 CABP2 CABP2 PDE4B PDE4B DRD4 DRD4 DRD2 DRD2 CABP1 CABP1 CACNA2D1 CACNA2D1 NIPSNAP2-2 NIPSNAP2-2 CABP4 CABP4 STRIT1 STRIT1 REM1-2 REM1-2 R3HDM1 R3HDM1 RGN-2 RGN-2 P2RY6 P2RY6 CRACR2A CRACR2A STAC3 STAC3 AKAP6 AKAP6 GNB5 GNB5 STIM2 STIM2 RRAD RRAD YWHAE YWHAE HAP1 HAP1 VMP1 VMP1 CBARP CBARP JSRP1 JSRP1 PRKACA PRKACA CALM3 CALM3 HRC HRC HPCAL1 HPCAL1 FKBP1B FKBP1B REM1 REM1 PLA2G6 PLA2G6 CAV3 CAV3 STAC STAC AHNAK AHNAK PKD2 PKD2 GEM GEM RGN RGN CACNA1F CACNA1F FMR1 FMR1 NOS1AP NOS1AP PPP3CC PPP3CC UBQLN1 UBQLN1 CACNB2 CACNB2 ANK2 ANK2 CLIC2 CLIC2 CABP5 CABP5 DMD DMD AKAP5 AKAP5 JPH1 JPH1 ASPH ASPH JPH3 JPH3 KCNE2 KCNE2 CACNB4 CACNB4 TRDN TRDN C4H4orf3 C4H4orf3 JPH4 JPH4 GPR35 GPR35 ADRA2A ADRA2A JPH2 JPH2 DRD3 DRD3 GSTO1 GSTO1 ENSPTRP00000063671 ENSPTRP00000063671 RYR2 RYR2 PPP3CB PPP3CB MRLN MRLN HTT HTT CLIC2-2 CLIC2-2 ENSPTRP00000075494 ENSPTRP00000075494 PLN PLN PLCG2 PLCG2 STIM1 STIM1 THADA THADA REM2 REM2 SMIM6 SMIM6 CDK5 CDK5 HSPA2 HSPA2 SRI SRI SRI-2 SRI-2 ATP1A2 ATP1A2 ENSPTRP00000082446 ENSPTRP00000082446 ENSPTRP00000082718 ENSPTRP00000082718 ATP2A1 ATP2A1 CALM1 CALM1 EHD3 EHD3 SUMO1-2 SUMO1-2 DMD-2 DMD-2 ENSPTRP00000085085 ENSPTRP00000085085 LOC459638 LOC459638 NIPSNAP2 NIPSNAP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPTRP00000085680annotation not available (88 aa)
SUMO1-3Small ubiquitin-related modifier. (98 aa)
ENSPTRP00000085903annotation not available (98 aa)
SLNSLN isoform 1. (31 aa)
CACNB1Calcium voltage-gated channel auxiliary subunit beta 1. (626 aa)
SELENONT0161445 isoform 2. (581 aa)
CACNB3Calcium channel, voltage-dependent, beta 3 subunit. (487 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (446 aa)
ENSPTRP00000088766annotation not available (199 aa)
SUMO1SUMO1 isoform 3. (146 aa)
ENSPTRP00000090392annotation not available (93 aa)
ENSPTRP00000090501annotation not available (192 aa)
STAC2SH3 and cysteine rich domain 2. (411 aa)
NOS1Nitric oxide synthase 1. (1468 aa)
CK820_G0029100SRI isoform 2. (98 aa)
R3HDM2R3HDM2 isoform 5. (1035 aa)
NPPANatriuretic peptide A. (153 aa)
HPCAHPCA isoform 3. (193 aa)
CASQ2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (399 aa)
CASQ1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (396 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane (By similarity). (303 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
PDE4DPhosphodiesterase. (809 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
CABP2Calcium binding protein 2. (229 aa)
PDE4BPhosphodiesterase. (736 aa)
DRD4DRD4 isoform 1; Belongs to the G-protein coupled receptor 1 family. (415 aa)
DRD2D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. (490 aa)
CABP1Calcium binding protein 1. (370 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1103 aa)
NIPSNAP2-2Glioblastoma amplified sequence. (286 aa)
CABP4Calcium binding protein 4. (275 aa)
STRIT1Small transmembrane regulator of ion transport 1. (35 aa)
REM1-2RRAD and GEM like GTPase 1. (298 aa)
R3HDM1R3H domain containing 1. (1102 aa)
RGN-2Regucalcin. (299 aa)
P2RY6Pyrimidinergic receptor P2Y6. (328 aa)
CRACR2ACRACR2A isoform 3. (732 aa)
STAC3SH3 and cysteine rich domain 3. (364 aa)
AKAP6A-kinase anchoring protein 6. (2319 aa)
GNB5GNB5 isoform 1. (409 aa)
STIM2STIM2 isoform 3. (841 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide; Belongs to the 14-3-3 family. (255 aa)
HAP1HAP1 isoform 2. (667 aa)
VMP1Vacuole membrane protein 1. (401 aa)
CBARPChromosome 19 open reading frame 26. (427 aa)
JSRP1Junctional sarcoplasmic reticulum protein 1. (331 aa)
PRKACAPRKACA isoform 7; Belongs to the protein kinase superfamily. (289 aa)
CALM3Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family. (149 aa)
HRCHRC isoform 2. (693 aa)
HPCAL1Hippocalcin-like protein 1. (193 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (298 aa)
PLA2G6Phospholipase A2 group VI. (806 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
STACSH3 and cysteine rich domain. (402 aa)
AHNAKAHNAK isoform 5. (5891 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (968 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (295 aa)
RGNRegucalcin (Senescence marker protein-30). (299 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1984 aa)
FMR1Fragile X mental retardation 1. (632 aa)
NOS1APNitric oxide synthase 1 adaptor protein. (506 aa)
PPP3CCSerine/threonine-protein phosphatase. (521 aa)
UBQLN1UBQLN1 isoform 1. (589 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (660 aa)
ANK2ANK2 isoform 1. (3957 aa)
CLIC2Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (247 aa)
CABP5Calcium binding protein 5. (173 aa)
DMDDMD isoform 3. (3685 aa)
AKAP5A-kinase anchoring protein 5. (427 aa)
JPH1Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (661 aa)
ASPHASPH isoform 1. (762 aa)
JPH3Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (748 aa)
KCNE2KCNE2 isoform 1. (123 aa)
CACNB4Calcium voltage-gated channel auxiliary subunit beta 4. (520 aa)
TRDNTRDN isoform 1. (730 aa)
C4H4orf3Chromosome 4 C4orf3 homolog. (199 aa)
JPH4Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (628 aa)
GPR35G protein-coupled receptor 35; Belongs to the G-protein coupled receptor 1 family. (340 aa)
ADRA2AAdrenergic, alpha-2A-, receptor. (465 aa)
JPH2Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (696 aa)
DRD3D(3) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation (By similarity). (400 aa)
GSTO1Glutathione S-transferase omega 1. (241 aa)
ENSPTRP00000063671annotation not available (122 aa)
RYR2RYR2 isoform 1. (4941 aa)
PPP3CBSerine/threonine-protein phosphatase. (526 aa)
MRLNMRLN isoform 2. (46 aa)
HTTHTT isoform 1. (3131 aa)
CLIC2-2Chloride intracellular channel 2. (247 aa)
ENSPTRP00000075494annotation not available (194 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
STIM1Stromal interaction molecule 1. (791 aa)
THADAThyroid adenoma associated. (1953 aa)
REM2GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (340 aa)
SMIM6Small integral membrane protein 6. (62 aa)
CDK5Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (311 aa)
HSPA2Heat shock 70kDa protein 2; Belongs to the heat shock protein 70 family. (642 aa)
SRISRI isoform 1. (205 aa)
SRI-2SRI isoform 5. (237 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
ENSPTRP00000082446annotation not available (194 aa)
ENSPTRP00000082718annotation not available (235 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1068 aa)
CALM1CALM1 isoform 3; Belongs to the calmodulin family. (150 aa)
EHD3EH domain containing 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (553 aa)
SUMO1-2Small ubiquitin-related modifier. (82 aa)
DMD-2Dystrophin. (643 aa)
ENSPTRP00000085085annotation not available (84 aa)
LOC45963814-3-3 protein epsilon-like. (255 aa)
NIPSNAP2Nipsnap homolog 2. (286 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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