STRINGSTRING
DRAXIN DRAXIN TNFRSF1B TNFRSF1B PINK1 PINK1 POU4F1 POU4F1 GCLM GCLM NES NES KIF14 KIF14 BTG2 BTG2 PM20D1 PM20D1 IL10 IL10 CD34 CD34 NENF NENF SLC30A10 SLC30A10 NRP1 NRP1 SIRT1 SIRT1 HRAS HRAS BTBD10 BTBD10 CNTF CNTF ZPR1 ZPR1 HYOU1 HYOU1 CBL CBL SORL1 SORL1 TIGAR TIGAR LRRK2 LRRK2 WNT1 WNT1 FAIM2 FAIM2 ERBB3 ERBB3 KDM2B KDM2B PARP2 PARP2 SNX6 SNX6 HIF1A HIF1A PSEN1 PSEN1 TGFB3 TGFB3 ALKBH1 ALKBH1 PSMC1 PSMC1 LGMN LGMN CHGA CHGA TYRO3 TYRO3 FOXB1 FOXB1 CORO1A CORO1A VPS35 VPS35 MT3 MT3 CX3CL1 CX3CL1 MEAK7 MEAK7 SERPINF1 SERPINF1 ARRB2 ARRB2 MAP2K4 MAP2K4 GRN GRN HDGF HDGF FGF21 FGF21 NTF4 NTF4 PRKCG PRKCG UCN UCN STAMBP STAMBP BCL2L1 BCL2L1 GDF5 GDF5 VSTM2L VSTM2L ADNP ADNP BHLHE23 BHLHE23 SOD1 SOD1 ADORA2A ADORA2A PLA2G3 PLA2G3 FBXO7 FBXO7 HMOX1 HMOX1 ATF4 ATF4 PPARA PPARA CHL1 CHL1 RHOA RHOA GBE1 GBE1 PLXND1 PLXND1 EIF4G1 EIF4G1 PPARGC1A PPARGC1A KDR KDR TERT-2 TERT-2 RETREG1 RETREG1 ISL1 ISL1 F2R F2R RASA1 RASA1 PCDHGA4-2 PCDHGA4-2 CPEB4 CPEB4 SNCB SNCB HSP90AB1 HSP90AB1 TFAP2D TFAP2D GCLC GCLC GFRAL GFRAL GRIK2 GRIK2 PRKN PRKN HIPK2 HIPK2 PTK2B PTK2B DNAJC5B DNAJC5B CNTFR CNTFR BARHL1 BARHL1 TRAF2 TRAF2 NONO NONO CITED1 CITED1 DLX1 DLX1 REST REST CSF3 CSF3 NCOA7 NCOA7 VPS54 VPS54 LIG4 LIG4 XRCC2 XRCC2 SIX4 SIX4 CTNNB1 CTNNB1 BHLHB9 BHLHB9 PTPRZ1 PTPRZ1 MTNR1B MTNR1B FZD9 FZD9 VEGFB VEGFB GDNF GDNF NAIP NAIP CD22-2 CD22-2 CRLF1 CRLF1 EN1 EN1 SLC1A1 SLC1A1 FOXQ1 FOXQ1 WNT3A WNT3A GBA GBA AARS1 AARS1 APOE APOE PATR-F PATR-F KIR2DL3 KIR2DL3 CX3CR1 CX3CR1 LOC100614689 LOC100614689 ENSPTRP00000060289 ENSPTRP00000060289 BDNF BDNF NMNAT3-2 NMNAT3-2 BIRC5 BIRC5 TERT TERT SYNGAP1 SYNGAP1 CD200 CD200 ENSPTRP00000062484 ENSPTRP00000062484 LOC100612404 LOC100612404 LOC101057146 LOC101057146 LOC737549 LOC737549 CK820_G0054728 CK820_G0054728 TSC1 TSC1 CHMP4B CHMP4B ADAM8 ADAM8 IL6ST IL6ST ENO2 ENO2 ENSPTRP00000065777 ENSPTRP00000065777 SEMA3E SEMA3E MSH2 MSH2 PRKCI PRKCI DTNBP1 DTNBP1 ENSPTRP00000067920 ENSPTRP00000067920 SLC7A11 SLC7A11 CCL2 CCL2 GFER GFER LOC100611078 LOC100611078 CSF1 CSF1 SIX1 SIX1 NGF NGF ENSPTRP00000070567 ENSPTRP00000070567 ENSPTRP00000070902 ENSPTRP00000070902 ENSPTRP00000071419 ENSPTRP00000071419 EN2 EN2 LOC470312 LOC470312 SLC23A2 SLC23A2 IL27RA IL27RA EN2-2 EN2-2 ENSPTRP00000073361 ENSPTRP00000073361 NRBP2 NRBP2 MAP3K12 MAP3K12 HTRA2 HTRA2 OXR1 OXR1 GHR GHR CLN8 CLN8 TMEM130 TMEM130 ENSPTRP00000075170 ENSPTRP00000075170 LOC454204 LOC454204 KIR3DL5 KIR3DL5 FGF8 FGF8 LOC100610002 LOC100610002 ENSPTRP00000076582 ENSPTRP00000076582 NEFL NEFL AGAP2 AGAP2 NTRK2 NTRK2 TFAP2B TFAP2B PARK7 PARK7 TMEM259 TMEM259 OXR1-2 OXR1-2 BRAF BRAF WFS1 WFS1 CDK5 CDK5 TOX3 TOX3 ENSPTRP00000081322 ENSPTRP00000081322 GABRB2 GABRB2 LOC100613849 LOC100613849 GSK3B GSK3B ATP13A2 ATP13A2 MECP2 MECP2 RACK1 RACK1 CK820_G0057017 CK820_G0057017 JAK2 JAK2 IKBKG IKBKG ENSPTRP00000082515 ENSPTRP00000082515 AKT1 AKT1 ENSPTRP00000082911 ENSPTRP00000082911 NTRK1 NTRK1 SOD2 SOD2 NR4A3 NR4A3 KRAS KRAS XRCC4 XRCC4 PIK3CA PIK3CA ROCK1 ROCK1 NRBP2-2 NRBP2-2 LOC454364 LOC454364 MDK MDK TAC1 TAC1 CEBPB CEBPB FGF20 FGF20 CCND1 CCND1 ENSPTRP00000086173 ENSPTRP00000086173 AMBRA1 AMBRA1 ENSPTRP00000086525 ENSPTRP00000086525 STXBP1 STXBP1 GPNMB GPNMB AXL AXL NMNAT1 NMNAT1 ENSPTRP00000087425 ENSPTRP00000087425 HSF1 HSF1 FZD1 FZD1 ENSPTRP00000088518 ENSPTRP00000088518 THAP11 THAP11 NR4A2 NR4A2 GABRA5 GABRA5 CLCF1 CLCF1 GPI GPI BRAF-2 BRAF-2 NFATC4 NFATC4 NTF3 NTF3 BCL2 BCL2 ENSPTRP00000090382 ENSPTRP00000090382 MEF2C MEF2C SNCA SNCA UNC5B UNC5B ENSPTRP00000091341 ENSPTRP00000091341 INPP5A INPP5A ANGPT1 ANGPT1 NDNF NDNF DNAJC5 DNAJC5 BAX BAX FZD1-2 FZD1-2 SIRT1-2 SIRT1-2 PPT1 PPT1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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DRAXINDraxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (349 aa)
TNFRSF1BTumor necrosis factor receptor superfamily, member 1B. (461 aa)
PINK1PTEN induced putative kinase 1. (581 aa)
POU4F1POU domain protein. (350 aa)
GCLMGlutamate-cysteine ligase, modifier subunit. (274 aa)
NESNES isoform 1; Belongs to the intermediate filament family. (1620 aa)
KIF14Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1648 aa)
BTG2BTG anti-proliferation factor 2. (158 aa)
PM20D1Peptidase M20 domain containing 1. (502 aa)
IL10Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (178 aa)
CD34CD34 isoform 1. (328 aa)
NENFNeuron derived neurotrophic factor; Belongs to the cytochrome b5 family. (172 aa)
SLC30A10Solute carrier family 30 member 10. (485 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
SIRT1SIRT1 isoform 2. (751 aa)
HRASV-Ha-ras Harvey rat sarcoma viral oncogene homolog. (189 aa)
BTBD10BTB (POZ) domain containing 10. (475 aa)
CNTFCiliary neurotrophic factor. (200 aa)
ZPR1Zinc finger protein 259. (459 aa)
HYOU1Hypoxia up-regulated 1. (999 aa)
CBLCas-Br-M (Murine) ecotropic retroviral transforming sequence. (906 aa)
SORL1Sortilin related receptor 1. (2214 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (270 aa)
LRRK2Leucine-rich repeat kinase 2. (2527 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
FAIM2FAIM2 isoform 2; Belongs to the BI1 family. (316 aa)
ERBB3V-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (Avian). (1353 aa)
KDM2BLysine (K)-specific demethylase 2B. (1336 aa)
PARP2Poly [ADP-ribose] polymerase. (570 aa)
SNX6Sorting nexin; Involved in several stages of intracellular trafficking. (418 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
ALKBH1AlkB homolog 1, histone H2A dioxygenase. (389 aa)
PSMC1Proteasome (Prosome, macropain) 26S subunit, ATPase, 1; Belongs to the AAA ATPase family. (440 aa)
LGMNLGMN isoform 1. (433 aa)
CHGACHGA isoform 1. (459 aa)
TYRO3TYRO3 protein tyrosine kinase. (890 aa)
FOXB1FOXB1 isoform 3. (325 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (796 aa)
MT3MT3 isoform 5; Belongs to the metallothionein superfamily. Type 1 family. (113 aa)
CX3CL1Chemokine (C-X3-C motif) ligand 1. (397 aa)
MEAK7MTOR associated protein, eak-7 homolog. (456 aa)
SERPINF1SERPINF1 isoform 1; Belongs to the serpin family. (418 aa)
ARRB2ARRB2 isoform 2. (430 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (410 aa)
GRNGranulin precursor. (593 aa)
HDGFHepatoma-derived growth factor. (256 aa)
FGF21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
NTF4NTF4 isoform 1; Belongs to the NGF-beta family. (210 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
UCNUCN isoform 1. (124 aa)
STAMBPSTAM binding protein. (424 aa)
BCL2L1BCL2L1 isoform 6. (233 aa)
GDF5GDF5 isoform 1. (501 aa)
VSTM2LV-set and transmembrane domain containing 2 like. (204 aa)
ADNPActivity-dependent neuroprotector homeobox. (1102 aa)
BHLHE23Basic helix-loop-helix family member e23. (241 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa)
PLA2G3PLA2G3 isoform 1. (509 aa)
FBXO7F-box protein 7. (522 aa)
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (311 aa)
ATF4Activating transcription factor 4 (Tax-responsive enhancer element B67). (351 aa)
PPARAPeroxisome proliferator-activated receptor alpha. (467 aa)
CHL1Cell adhesion molecule with homology to L1CAM (Close homolog of L1). (1225 aa)
RHOARas homolog family member A. (193 aa)
GBE1Glucan (1,4-alpha-), branching enzyme 1. (818 aa)
PLXND1PLXND1 isoform 1. (1925 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1. (1559 aa)
PPARGC1APPARG coactivator 1 alpha. (809 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
TERT-2Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (762 aa)
RETREG1Family with sequence similarity 134, member B. (497 aa)
ISL1ISL LIM homeobox 1. (349 aa)
F2RCoagulation factor II (Thrombin) receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa)
RASA1RAS p21 protein activator (GTPase activating protein) 1. (1047 aa)
PCDHGA4-2Protocadherin gamma-C5; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. (944 aa)
CPEB4Cytoplasmic polyadenylation element binding protein 4. (729 aa)
SNCBBeta-synuclein; Belongs to the synuclein family. (134 aa)
HSP90AB1HSP90AB1 isoform 1. (688 aa)
TFAP2DTranscription factor AP-2 delta. (452 aa)
GCLCGlutamate-cysteine ligase, catalytic subunit. (637 aa)
GFRALGDNF family receptor alpha like. (394 aa)
GRIK2Glutamate ionotropic receptor kainate type subunit 2. (908 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
HIPK2Homeodomain interacting protein kinase 2. (1198 aa)
PTK2BPTK2B protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
DNAJC5BDnaJ heat shock protein family (Hsp40) member C5 beta. (199 aa)
CNTFRCNTFR isoform 1. (372 aa)
BARHL1BarH like homeobox 1. (327 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
NONOnon-POU domain containing octamer binding. (471 aa)
CITED1Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (219 aa)
DLX1Distal-less homeobox 1. (255 aa)
RESTRE1 silencing transcription factor. (1097 aa)
CSF3Colony stimulating factor 3 (Granulocyte). (204 aa)
NCOA7Nuclear receptor coactivator 7. (942 aa)
VPS54Vacuolar protein sorting 54 homolog. (977 aa)
LIG4DNA ligase. (911 aa)
XRCC2X-ray repair complementing defective repair in Chinese hamster cells 2. (280 aa)
SIX4SIX homeobox 4. (781 aa)
CTNNB1Catenin (Cadherin-associated protein), beta 1, 88kDa. (781 aa)
BHLHB9Basic helix-loop-helix domain containing, class B, 9. (547 aa)
PTPRZ1Protein tyrosine phosphatase receptor type Z1. (2315 aa)
MTNR1BMelatonin receptor 1B; Belongs to the G-protein coupled receptor 1 family. (362 aa)
FZD9Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (591 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (207 aa)
GDNFGlial cell derived neurotrophic factor. (228 aa)
NAIPNLR family apoptosis inhibitory protein. (1403 aa)
CD22-2B-cell receptor CD22. (626 aa)
CRLF1Cytokine receptor like factor 1. (459 aa)
EN1Homeobox protein engrailed-like. (396 aa)
SLC1A1Amino acid transporter. (524 aa)
FOXQ1FOXQ1 isoform 1. (403 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
GBALysosomal acid glucosylceramidase; Glucosylceramidase that catalyzes, within the lysosomal compartment, the hydrolysis of glucosylceramide/GlcCer into free ceramide and glucose. Thereby, plays a central role in the degradation of complex lipids and the turnover of cellular membranes. Through the production of ceramides, participates to the PKC-activated salvage pathway of ceramide formation. Also plays a role in cholesterol metabolism. May either catalyze the glucosylation of cholesterol, through a transglucosylation reaction that transfers glucose from glucosylceramide to cholesterol. [...] (536 aa)
AARS1Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (968 aa)
APOEApolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (317 aa)
PATR-FPatr class I histocompatibility antigen, CH28 alpha chain; Involved in the presentation of foreign antigens to the immune system. (442 aa)
KIR2DL3KIR2DL3 isoform 1. (441 aa)
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (387 aa)
LOC100614689BCL2-related ovarian killer. (207 aa)
ENSPTRP00000060289annotation not available (844 aa)
BDNFBrain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (329 aa)
NMNAT3-2Nicotinamide nucleotide adenylyltransferase 3. (261 aa)
BIRC5Baculoviral IAP repeat containing 5. (165 aa)
TERTTelomerase reverse transcriptase. (360 aa)
SYNGAP1Synaptic Ras GTPase activating protein 1. (1345 aa)
CD200CD200 isoform 4. (294 aa)
ENSPTRP00000062484annotation not available (224 aa)
LOC100612404Glucosylceramidase-like. (495 aa)
LOC101057146Putative charged multivesicular body protein 4B-like protein CHMP4BP1. (194 aa)
LOC737549Battenin. (418 aa)
CK820_G0054728MECP2 isoform 14. (493 aa)
TSC1TSC complex subunit 1. (1164 aa)
CHMP4BCharged multivesicular body protein 4B. (271 aa)
ADAM8ADAM metallopeptidase domain 8. (824 aa)
IL6STInterleukin 6 signal transducer (Gp130, oncostatin M receptor). (918 aa)
ENO2Enolase 2 (Gamma, neuronal). (434 aa)
ENSPTRP00000065777annotation not available (412 aa)
SEMA3ESEMA3E isoform 1; Belongs to the semaphorin family. (775 aa)
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (865 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)
DTNBP1Dystrobrevin binding protein 1. (351 aa)
ENSPTRP00000067920annotation not available (392 aa)
SLC7A11Solute carrier family 7, (Cationic amino acid transporter, y+ system) member 11. (515 aa)
CCL2C-C motif chemokine. (109 aa)
GFERSulfhydryl oxidase. (204 aa)
LOC100611078Cyclic AMP-dependent transcription factor ATF-4 pseudogene. (318 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (585 aa)
SIX1SIX homeobox 1. (284 aa)
NGFBeta-nerve growth factor; Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival (By similarity). The immature NGF precursor (proNGF) functions as ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone colla [...] (123 aa)
ENSPTRP00000070567annotation not available (277 aa)
ENSPTRP00000070902annotation not available (168 aa)
ENSPTRP00000071419annotation not available (371 aa)
EN2Engrailed homeobox 2. (338 aa)
LOC47031226S proteasome regulatory subunit 4 pseudogene. (374 aa)
SLC23A2Solute carrier family 23 (Nucleobase transporters), member 2. (650 aa)
IL27RAInterleukin 27 receptor subunit alpha. (554 aa)
EN2-2Homeobox protein engrailed-like. (336 aa)
ENSPTRP00000073361annotation not available (388 aa)
NRBP2Nuclear receptor binding protein 2. (501 aa)
MAP3K12Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (893 aa)
HTRA2HtrA serine peptidase 2. (458 aa)
OXR1OXR1 isoform 3. (872 aa)
GHRGrowth hormone receptor. (645 aa)
CLN8Ceroid-lipofuscinosis neuronal protein 8. (286 aa)
TMEM130Transmembrane protein 130. (435 aa)
ENSPTRP00000075170annotation not available (461 aa)
LOC454204Non-POU domain-containing octamer-binding protein. (445 aa)
KIR3DL5Pan troglodytes killer cell immunoglobulin-like receptor (KIR3DL5), mRNA. (436 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
LOC100610002IKBKG isoform 9. (401 aa)
ENSPTRP00000076582annotation not available (377 aa)
NEFLNeurofilament light; Belongs to the intermediate filament family. (543 aa)
AGAP2ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (1192 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
TFAP2BTranscription factor AP-2 beta. (467 aa)
PARK7PARK7 isoform 1. (189 aa)
TMEM259Chromosome 19 open reading frame 6. (620 aa)
OXR1-2Oxidation resistance 1. (198 aa)
BRAFBRAF isoform 1; Belongs to the protein kinase superfamily. (767 aa)
WFS1WFS1 isoform 1. (890 aa)
CDK5Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (311 aa)
TOX3TOX high mobility group box family member 3. (589 aa)
ENSPTRP00000081322annotation not available (396 aa)
GABRB2Gamma-aminobutyric acid type A receptor beta2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (512 aa)
LOC100613849Uncharacterized LOC100613849. (148 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (481 aa)
ATP13A2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1195 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
RACK1Receptor for activated C kinase 1. (321 aa)
CK820_G0057017CLN3 isoform 55. (42 aa)
JAK2Tyrosine-protein kinase. (1143 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (487 aa)
ENSPTRP00000082515annotation not available (336 aa)
AKT1AKT1 isoform 3; Belongs to the protein kinase superfamily. (480 aa)
ENSPTRP00000082911annotation not available (354 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
SOD2Superoxide dismutase [Mn], mitochondrial; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (238 aa)
NR4A3Nuclear receptor subfamily 4 group A member 3. (637 aa)
KRASV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
XRCC4X-ray repair complementing defective repair in Chinese hamster cells 4. (334 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1034 aa)
ROCK1Rho-associated protein kinase 1; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of DAPK3, GFAP, LIMK1, LIMK2, MYL9/MLC2, TPPP, PFN1 and PPP1R12A. Phosphorylates FHOD1 and acts synergistically with it to promote SRC-dependent non-apoptotic plasma membrane blebbing. Phosphorylates JIP3 and regulates the recruitment of JNK to JIP3 upon UVB-induced stress (By simi [...] (1368 aa)
NRBP2-2Nuclear receptor binding protein 2. (501 aa)
LOC454364Sulfotransferase; Belongs to the sulfotransferase 1 family. (295 aa)
MDKMidkine (Neurite growth-promoting factor 2). (143 aa)
TAC1TAC1 isoform 1. (134 aa)
CEBPBCCAAT/enhancer-binding protein. (347 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
CCND1CCND1 isoform 1; Belongs to the cyclin family. (295 aa)
ENSPTRP00000086173annotation not available (566 aa)
AMBRA1AMBRA1 isoform 6. (1298 aa)
ENSPTRP00000086525annotation not available (336 aa)
STXBP1Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family. (603 aa)
GPNMBGPNMB isoform 2. (574 aa)
AXLAXL receptor tyrosine kinase. (894 aa)
NMNAT1Nicotinamide-nucleotide adenylyltransferase. (279 aa)
ENSPTRP00000087425annotation not available (336 aa)
HSF1Heat shock transcription factor 1. (529 aa)
FZD1FZD1 isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (580 aa)
ENSPTRP00000088518annotation not available (428 aa)
THAP11THAP11 isoform 1. (308 aa)
NR4A2Nuclear receptor subfamily 4, group A, member 2. (598 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
CLCF1Cardiotrophin-like cytokine factor 1 isoform X1. (225 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (597 aa)
BRAF-2BRAF isoform 2. (766 aa)
NFATC4Nuclear factor of activated T cells 4. (933 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (275 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
ENSPTRP00000090382annotation not available (493 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
SNCAAlpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...] (140 aa)
UNC5BUNC5B isoform 2. (945 aa)
ENSPTRP00000091341annotation not available (379 aa)
INPP5AINPP5A isoform 1. (398 aa)
ANGPT1ANGPT1 isoform 2. (498 aa)
NDNFNDNF isoform 1. (568 aa)
DNAJC5DnaJ heat shock protein family (Hsp40) member C5. (198 aa)
BAXBAX isoform 7. (123 aa)
FZD1-2Frizzled class receptor 1. (580 aa)
SIRT1-2Sirtuin 1. (751 aa)
PPT1Palmitoyl-protein thioesterase 1. (335 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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