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| | OSBP | Oxysterol-binding protein; Belongs to the OSBP family. (807 aa) |
| | ACER3 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (267 aa) |
| | TYR | TYR isoform 1. (529 aa) |
| | APOA5 | Apolipoprotein A5. (366 aa) |
| | APOA4 | Apolipoprotein A4. (396 aa) |
| | APOA1 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility (By similarity). (267 aa) |
| | CYP27B1 | Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa) |
| | PAH | Phenylalanine hydroxylase. (452 aa) |
| | MVK | Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (396 aa) |
| | KL | KL isoform 1. (1012 aa) |
| | PCK2 | Phosphoenolpyruvate carboxykinase 2, mitochondrial. (640 aa) |
| | ENSPTRP00000084510 | annotation not available (456 aa) |
| | ENSPTRP00000084501 | annotation not available (332 aa) |
| | ENSPTRP00000084413 | annotation not available (332 aa) |
| | PDXK | Pyridoxal (Pyridoxine, vitamin B6) kinase. (309 aa) |
| | TRPC1 | TRPC1 isoform 3; Belongs to the transient receptor (TC 1.A.4) family. (795 aa) |
| | ENSPTRP00000082047 | annotation not available (353 aa) |
| | TM7SF2 | Transmembrane 7 superfamily member 2. (418 aa) |
| | CYP3A4 | Cytochrome P450 family 3 subfamily A member 4. (507 aa) |
| | CYB5R3 | NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (334 aa) |
| | LOC466046 | 3-keto-steroid reductase-like. (305 aa) |
| | ENSPTRP00000065447 | annotation not available (354 aa) |
| | NSDHL-2 | NAD(P) dependent steroid dehydrogenase-like. (373 aa) |
| | CK820_G0033603 | PPIP5K1 isoform 7. (1160 aa) |
| | ENSPTRP00000081042 | annotation not available (262 aa) |
| | ENSPTRP00000080550 | Apolipoprotein A-I Proapolipoprotein A-I Truncated apolipoprotein A-I. (267 aa) |
| | SQLE | Squalene epoxidase. (574 aa) |
| | DCT | Dopachrome tautomerase. (552 aa) |
| | OSBPL9 | Oxysterol-binding protein; Belongs to the OSBP family. (746 aa) |
| | ENSPTRP00000079214 | annotation not available (345 aa) |
| | SPTSSA | Serine palmitoyltransferase small subunit A. (71 aa) |
| | GATA3 | GATA binding protein 3. (444 aa) |
| | CYP7B1 | Cytochrome P450, family 7, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (506 aa) |
| | LSS | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (732 aa) |
| | ASAH1 | Acid ceramidase subunit alpha; Lysosomal ceramidase that hydrolyzes sphingolipid ceramides into sphingosine and free fatty acids at acidic pH (By similarity). Ceramides, sphingosine, and its phosphorylated form sphingosine-1- phosphate are bioactive lipids that mediate cellular signaling pathways regulating several biological processes including cell proliferation, apoptosis and differentiation (By similarity). Has a higher catalytic efficiency towards C12-ceramides versus other ceramides (By similarity). Also catalyzes the reverse reaction allowing the synthesis of ceramides from fatt [...] (411 aa) |
| | HSD3B7 | Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7; Belongs to the 3-beta-HSD family. (369 aa) |
| | LOC100612404 | Glucosylceramidase-like. (495 aa) |
| | ENSPTRP00000062399 | annotation not available (83 aa) |
| | LOC741304 | Dehydrodolichyl diphosphate synthase complex subunit NUS1. (278 aa) |
| | PGP | Phosphoglycolate phosphatase; Belongs to the HAD-like hydrolase superfamily. (321 aa) |
| | SPTLC3 | Serine palmitoyltransferase, long chain base subunit 3. (552 aa) |
| | MFSD12 | Major facilitator superfamily domain containing 12. (480 aa) |
| | GCH1 | GTP cyclohydrolase 1. (250 aa) |
| | SPHK1 | Sphingosine kinase 1. (470 aa) |
| | GBA | Lysosomal acid glucosylceramidase; Glucosylceramidase that catalyzes, within the lysosomal compartment, the hydrolysis of glucosylceramide/GlcCer into free ceramide and glucose. Thereby, plays a central role in the degradation of complex lipids and the turnover of cellular membranes. Through the production of ceramides, participates to the PKC-activated salvage pathway of ceramide formation. Also plays a role in cholesterol metabolism. May either catalyze the glucosylation of cholesterol, through a transglucosylation reaction that transfers glucose from glucosylceramide to cholesterol. [...] (536 aa) |
| | HAND2 | Heart and neural crest derivatives expressed 2. (217 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (574 aa) |
| | NPC1L1 | NPC1 like intracellular cholesterol transporter 1. (1359 aa) |
| | PTS | 6-pyruvoyl tetrahydrobiopterin synthase. (145 aa) |
| | CCDC160 | Coiled-coil domain containing 160. (325 aa) |
| | ACLY | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. (1134 aa) |
| | CES1 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (537 aa) |
| | DHCR7 | 7-dehydrocholesterol reductase. (475 aa) |
| | OSBPL7 | Oxysterol-binding protein; Belongs to the OSBP family. (842 aa) |
| | PPIP5K1 | Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1429 aa) |
| | G6PD | Glucose-6-phosphate dehydrogenase. (560 aa) |
| | NSDHL | NAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family. (373 aa) |
| | CITED1 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (219 aa) |
| | CYP11B1 | CYP11B1 isoform 5; Belongs to the cytochrome P450 family. (577 aa) |
| | ACER2 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa) |
| | PSAT1 | Phosphoserine aminotransferase. (370 aa) |
| | IPPK | Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (501 aa) |
| | DBH | Dopamine beta-hydroxylase. (617 aa) |
| | HSD17B10 | Hydroxysteroid (17-beta) dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa) |
| | CYP39A1 | Cytochrome P450, family 39, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (471 aa) |
| | AKR1C3 | Aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II). (323 aa) |
| | PARK7 | PARK7 isoform 1. (189 aa) |
| | ENSPTRP00000078503 | annotation not available (351 aa) |
| | TPH1 | Tryptophan hydroxylase 1. (444 aa) |
| | PPIP5K2 | Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1278 aa) |
| | SPTLC1 | Aminotran_1_2 domain-containing protein. (463 aa) |
| | PRKAG2-2 | PRKAG2 isoform 10. (204 aa) |
| | SPTSSB | Serine palmitoyltransferase small subunit B. (76 aa) |
| | DDT | DDT isoform 2. (166 aa) |
| | HMGCR | 3-hydroxy-3-methylglutaryl coenzyme A reductase. (888 aa) |
| | ENSPTRP00000076636 | annotation not available (229 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) |
| | CYB5R2 | NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (276 aa) |
| | SREBF1 | SREBF1 isoform 6. (1177 aa) |
| | OSBPL3 | Oxysterol-binding protein; Belongs to the OSBP family. (888 aa) |
| | ENSPTRP00000075411 | annotation not available (325 aa) |
| | ERG28 | Chromosome 14 open reading frame 1. (140 aa) |
| | SPTLC2 | Serine palmitoyltransferase, long chain base subunit 2. (564 aa) |
| | CYP46A1 | Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family. (500 aa) |
| | ITPKA | Kinase; Belongs to the inositol phosphokinase (IPK) family. (461 aa) |
| | SLC24A5 | Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (500 aa) |
| | SLC27A2 | Solute carrier family 27 member 2. (620 aa) |
| | HDC | Histidine decarboxylase. (662 aa) |
| | CYP19A1 | Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. (503 aa) |
| | CACNA1H | CACNA1H isoform 1. (2240 aa) |
| | MVD | Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (400 aa) |
| | CTNS | Cystinosin, lysosomal cystine transporter. (400 aa) |
| | ALOX15 | Arachidonate 15-lipoxygenase. (662 aa) |
| | ALOX12 | Arachidonate 12-lipoxygenase, 12S type. (663 aa) |
| | ALOX15B | Arachidonate 15-lipoxygenase, type B. (676 aa) |
| | PNMT | Phenylethanolamine N-methyltransferase. (282 aa) |
| | PNPO | Pyridoxamine 5'-phosphate oxidase. (261 aa) |
| | IMPA2 | Inositol-1-monophosphatase. (288 aa) |
| | OSBPL1A | Oxysterol-binding protein; Belongs to the OSBP family. (950 aa) |
| | ACAA2 | Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa) |
| | ACER1 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (264 aa) |
| | ENSPTRP00000092461 | annotation not available (453 aa) |
| | ENSPTRP00000092441 | Inositol monophosphatase 1-like isoform X1. (313 aa) |
| | ENSPTRP00000091576 | annotation not available (261 aa) |
| | ENSPTRP00000091066 | annotation not available (366 aa) |
| | DDC | Dopa decarboxylase. (489 aa) |
| | SNCA | Alpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...] (140 aa) |
| | ASAH2 | Neutral ceramidase. (780 aa) |
| | PRKAG2 | PRKAG2 isoform 4. (445 aa) |
| | ENSPTRP00000090023 | annotation not available (349 aa) |
| | ENSPTRP00000089932 | annotation not available (392 aa) |
| | BAAT | Bile acid-CoA:amino acid N-acyltransferase. (418 aa) |
| | PMEL | PMEL isoform 1. (705 aa) |
| | NR4A2 | Nuclear receptor subfamily 4, group A, member 2. (598 aa) |
| | OSBPL6 | Oxysterol-binding protein; Belongs to the OSBP family. (967 aa) |
| | ABCB11 | ATP binding cassette subfamily B member 11. (1321 aa) |
| | ENSPTRP00000088589 | annotation not available (206 aa) |
| | TPH2 | Tryptophan hydroxylase 2. (490 aa) |
| | MOXD1 | MOXD1 isoform 1. (613 aa) |
| | FDFT1 | Farnesyl-diphosphate farnesyltransferase 1. (468 aa) |
| | OCA2 | OCA2 isoform 2. (838 aa) |
| | LOC747294 | D-dopachrome decarboxylase. (147 aa) |
| | ENSPTRP00000086066 | annotation not available (83 aa) |
| | ENSPTRP00000085845 | annotation not available (486 aa) |
| | SRD5A2 | 3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (254 aa) |
| | PLPP6 | Phosphatidic acid phosphatase type 2 domain containing 2. (300 aa) |
| | DAO | D-amino acid oxidase. (347 aa) |
| | HNF1A | HNF1 homeobox A. (662 aa) |
| | ISYNA1 | ISYNA1 isoform 6. (547 aa) |
| | ITPKC | Kinase; Belongs to the inositol phosphokinase (IPK) family. (683 aa) |
| | SPHK2 | Sphingosine kinase 2. (255 aa) |
| | SLC27A5 | SLC27A5 isoform 3. (690 aa) |
| | INSIG2 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa) |
| | CYP27A1 | Cytochrome P450, family 27, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (531 aa) |
| | TMEM130 | Transmembrane protein 130. (435 aa) |
| | ENSPTRP00000075003 | annotation not available (254 aa) |
| | SPR | Sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase). (261 aa) |
| | AMACR | Alpha-methylacyl-CoA racemase isoform X2. (394 aa) |
| | ABCA2 | ABCA2 isoform 8. (2364 aa) |
| | HSD17B3 | Hydroxysteroid 17-beta dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (310 aa) |
| | ENSPTRP00000072545 | annotation not available (345 aa) |
| | EBP | Emopamil binding protein (Sterol isomerase). (230 aa) |
| | ENSPTRP00000072249 | annotation not available (396 aa) |
| | TYRP1 | TYRP1 isoform 6. (578 aa) |
| | SLC45A2 | Solute carrier family 45 member 2. (530 aa) |
| | IP6K2 | Kinase; Belongs to the inositol phosphokinase (IPK) family. (481 aa) |
| | ENSPTRP00000070902 | annotation not available (168 aa) |
| | PER2 | Period circadian regulator 2. (1255 aa) |
| | ACOT8 | Acyl-CoA thioesterase 8. (319 aa) |
| | PCK1 | Phosphoenolpyruvate carboxykinase 1. (622 aa) |
| | OSBPL2 | Oxysterol-binding protein; Belongs to the OSBP family. (480 aa) |
| | CYP8B1 | Cytochrome P450 family 8 subfamily B member 1; Belongs to the cytochrome P450 family. (496 aa) |
| | IP6K1 | Kinase; Belongs to the inositol phosphokinase (IPK) family. (441 aa) |
| | QDPR | Quinoid dihydropteridine reductase. (244 aa) |
| | SRD5A3 | Steroid 5 alpha-reductase 3. (318 aa) |
| | PTAFR | Platelet activating factor receptor; Belongs to the G-protein coupled receptor 1 family. (342 aa) |
| | MSMO1 | Sterol-C4-methyl oxidase-like; Belongs to the sterol desaturase family. (293 aa) |
| | CYP51A1-2 | Cytochrome P450 family 51 subfamily A member 1. (509 aa) |
| | GATD1 | Glutamine amidotransferase like class 1 domain containing 1. (220 aa) |
| | CK820_G0027885 | HSD17B7 isoform 10. (84 aa) |
| | IMPA1 | Inositol-1-monophosphatase. (332 aa) |
| | PLTP | PLTP isoform 3. (500 aa) |
| | CK820_G0026077 | ISYNA1 isoform 5. (541 aa) |
| | DHDDS | Dehydrodolichyl diphosphate synthase subunit. (334 aa) |
| | DDTL | DDT isoform 5. (134 aa) |
| | SC5D | Sterol-C5-desaturase; Belongs to the sterol desaturase family. (299 aa) |
| | ABCD3 | ATP-binding cassette, sub-family D (ALD), member 3. (659 aa) |
| | SLC6A3 | Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (620 aa) |
| | HMGCS1 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (601 aa) |
| | DHFR | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. (187 aa) |
| | PCBD2 | Pterin-4 alpha-carbinolamine dehydratase 2. (130 aa) |
| | FAXDC2 | Fatty acid hydroxylase domain containing 2; Belongs to the sterol desaturase family. (310 aa) |
| | IP6K3 | Kinase; Belongs to the inositol phosphokinase (IPK) family. (410 aa) |
| | NUS1 | Nuclear undecaprenyl pyrophosphate synthase 1 homolog. (293 aa) |
| | CYP51A1 | Cytochrome P450, family 51, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (509 aa) |
| | CFTR | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1480 aa) |
| | GPR37 | G protein-coupled receptor 37. (613 aa) |
| | AKR1D1 | Aldo-keto reductase family 1 member D1. (326 aa) |
| | INSIG1 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (277 aa) |
| | CYP7A1 | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (504 aa) |
| | SCP2 | Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. (547 aa) |
| | DHCR24 | 24-dehydrocholesterol reductase. (516 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (552 aa) |
| | HMGCS2 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa) |
| | PMVK | Phosphomevalonate kinase. (192 aa) |
| | FDPS | Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. (419 aa) |
| | CYB5R1 | NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (305 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | LBR | Lamin B receptor. (615 aa) |
| | ITPKB | Kinase; Belongs to the inositol phosphokinase (IPK) family. (946 aa) |
| | ARV1 | ARV1 homolog, fatty acid homeostasis modulator. (271 aa) |
| | IDI1 | Isopentenyl-diphosphate delta isomerase 1. (284 aa) |
| | AKR1C4 | Aldo-keto reductase family 1 member C4. (323 aa) |
| | HSD17B7 | Hydroxysteroid (17-beta) dehydrogenase 7. (362 aa) |
| | IPMK | Kinase; Belongs to the inositol phosphokinase (IPK) family. (416 aa) |
| | PCBD1 | Pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha. (104 aa) |
| | CH25H | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. (272 aa) |
| | GOT1 | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] (413 aa) |
| | TH | Tyrosine hydroxylase. (528 aa) |
| | CYP2R1 | Cytochrome P450 family 2 subfamily R member 1; Belongs to the cytochrome P450 family. (501 aa) |
| | LDHC | L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (311 aa) |
