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ENSPTRP00000079594 ENSPTRP00000079594 PACC1 PACC1 ANO2 ANO2 GABRB3 GABRB3 SLC1A3 SLC1A3 ENSPTRP00000082726 ENSPTRP00000082726 ENSPTRP00000082912 ENSPTRP00000082912 ENSPTRP00000082975 ENSPTRP00000082975 CLCN3 CLCN3 CLCNKA CLCNKA SLC6A2 SLC6A2 GABRA5 GABRA5 GABRQ-2 GABRQ-2 TTYH3-2 TTYH3-2 GLRA2 GLRA2 GABRG3 GABRG3 GABRA3-2 GABRA3-2 GABRB2 GABRB2 CLCN6 CLCN6 CLCNKB CLCNKB CLIC4 CLIC4 BEST4 BEST4 BSND BSND CLCA2 CLCA2 CLCA4 CLCA4 CLCA1 CLCA1 CLCC1 CLCC1 SLC18A2 SLC18A2 ANO5 ANO5 SLC4A8 SLC4A8 BEST3 BEST3 CLCN7 CLCN7 SLC12A3 SLC12A3 SLC6A4 SLC6A4 SLC4A1 SLC4A1 TTYH2 TTYH2 BEST2 BEST2 ANO8 ANO8 FXYD1 FXYD1 SLC17A7 SLC17A7 SLC1A4 SLC1A4 PCYOX1 PCYOX1 ANO7 ANO7 CLDN17 CLDN17 SLC6A1 SLC6A1 ANO10 ANO10 SLC26A6 SLC26A6 GABRG1 GABRG1 GABRA4 GABRA4 GABRB1 GABRB1 GLRA3 GLRA3 SLC12A7 SLC12A7 SLC6A3 SLC6A3 SLC12A2 SLC12A2 GLRA1 GLRA1 NMUR2 NMUR2 GABRA6 GABRA6 GABRP GABRP CLIC1 CLIC1 GABRR1 GABRR1 SLC22A1 SLC22A1 TTYH3 TTYH3 SLC26A4 SLC26A4 CFTR CFTR CLCN1 CLCN1 LRRC8A LRRC8A CLIC3 CLIC3 GLRA4 GLRA4 GABRE GABRE GABRA3 GABRA3 GABRQ GABRQ SLC26A3 SLC26A3 CLCN5 CLCN5 CASR CASR SLC26A8 SLC26A8 SLC26A1 SLC26A1 SLC17A6 SLC17A6 SLC12A9 SLC12A9 CLIC2 CLIC2 TTYH1 TTYH1 SLC1A1 SLC1A1 SLC26A9 SLC26A9 SLC18A1 SLC18A1 SLC26A7 SLC26A7 SLC12A8 SLC12A8 GABRG2 GABRG2 SLC12A1 SLC12A1 ANO4 ANO4 ANO9 ANO9 GABRA2 GABRA2 CLDN4 CLDN4 SLC12A4 SLC12A4 LOC469373 LOC469373 CLCN1-2 CLCN1-2 SLC26A10 SLC26A10 GABRD GABRD ANO6 ANO6 CK820_G0035770 CK820_G0035770 CLIC2-2 CLIC2-2 CLCN2 CLCN2 CLIC5 CLIC5 ENSPTRP00000068002 ENSPTRP00000068002 BEST1 BEST1 CLIC6 CLIC6 GLRB GLRB SLC26A5 SLC26A5 GABRR3 GABRR3 GABRA1 GABRA1 CLDN4-2 CLDN4-2 CLCN4 CLCN4 PPP1R7 PPP1R7 ENSPTRP00000076491 ENSPTRP00000076491 GABRR2 GABRR2 ANO1 ANO1 SLC26A2 SLC26A2 ANO3 ANO3 SLC17A8 SLC17A8 SLC12A6 SLC12A6 SLC12A5 SLC12A5 FXYD3 FXYD3
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPTRP00000079594annotation not available (460 aa)
PACC1TMEM206 isoform 1. (411 aa)
ANO2Anoctamin. (999 aa)
GABRB3Gamma-aminobutyric acid type A receptor beta3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (529 aa)
SLC1A3Amino acid transporter. (542 aa)
ENSPTRP00000082726annotation not available (506 aa)
ENSPTRP00000082912annotation not available (153 aa)
ENSPTRP00000082975annotation not available (212 aa)
CLCN3Chloride channel protein. (866 aa)
CLCNKAChloride channel protein. (686 aa)
SLC6A2Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (617 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
GABRQ-2Gamma-aminobutyric acid type A receptor theta subunit. (632 aa)
TTYH3-2Protein tweety homolog; Probable chloride channel. (526 aa)
GLRA2Glycine receptor alpha 2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (452 aa)
GABRG3Gamma-aminobutyric acid type A receptor gamma3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (467 aa)
GABRA3-2Gamma-aminobutyric acid type A receptor alpha3 subunit. (492 aa)
GABRB2Gamma-aminobutyric acid type A receptor beta2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (512 aa)
CLCN6CLCN6 isoform 4; Belongs to the chloride channel (TC 2.A.49) family. (952 aa)
CLCNKBChloride channel protein. (699 aa)
CLIC4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (253 aa)
BEST4Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (473 aa)
BSNDBSND isoform 1. (320 aa)
CLCA2CLCA2 isoform 1. (943 aa)
CLCA4CLCA4 isoform 1. (939 aa)
CLCA1CLCA1 isoform 1. (914 aa)
CLCC1Chloride channel CLIC-like 1. (551 aa)
SLC18A2Solute carrier family 18 member A2. (514 aa)
ANO5Anoctamin. (913 aa)
SLC4A8Anion exchange protein. (1093 aa)
BEST3Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (668 aa)
CLCN7Chloride channel protein. (805 aa)
SLC12A3SLC12A3 isoform 1. (1030 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (630 aa)
SLC4A1Anion exchange protein. (921 aa)
TTYH2Protein tweety homolog; Probable chloride channel; Belongs to the tweety family. (534 aa)
BEST2Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (509 aa)
ANO8Anoctamin. (1234 aa)
FXYD1FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (81 aa)
SLC17A7SLC17A7 isoform 1. (570 aa)
SLC1A4Solute carrier family 1 (Glutamate/neutral amino acid transporter), member 4. (532 aa)
PCYOX1Prenylcysteine oxidase 1. (505 aa)
ANO7Anoctamin. (933 aa)
CLDN17Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa)
SLC6A1Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (599 aa)
ANO10Anoctamin. (660 aa)
SLC26A6Solute carrier family 26, member 6. (761 aa)
GABRG1Gamma-aminobutyric acid type A receptor gamma1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (465 aa)
GABRA4Gamma-aminobutyric acid type A receptor alpha4 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (554 aa)
GABRB1Gamma-aminobutyric acid type A receptor beta1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (474 aa)
GLRA3Glycine receptor alpha 3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (464 aa)
SLC12A7SLC12A7 isoform 4. (1058 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (620 aa)
SLC12A2SLC12A2 isoform 1. (1211 aa)
GLRA1GLRA1 isoform 3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (451 aa)
NMUR2Neuromedin U receptor 2; Belongs to the G-protein coupled receptor 1 family. (415 aa)
GABRA6GABRA6 isoform 3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (453 aa)
GABRPGamma-aminobutyric acid type A receptor pi subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (440 aa)
CLIC1Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (241 aa)
GABRR1Gamma-aminobutyric acid type A receptor rho1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (479 aa)
SLC22A1SLC22A1 isoform 2. (552 aa)
TTYH3Protein tweety homolog; Probable chloride channel; Belongs to the tweety family. (523 aa)
SLC26A4Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (780 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1480 aa)
CLCN1Chloride channel protein. (989 aa)
LRRC8ALeucine rich repeat containing 8 family, member A. (810 aa)
CLIC3Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (236 aa)
GLRA4Glycine receptor alpha 4; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (418 aa)
GABREGamma-aminobutyric acid type A receptor epsilon subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (506 aa)
GABRA3Gamma-aminobutyric acid type A receptor alpha3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (492 aa)
GABRQGamma-aminobutyric acid type A receptor theta subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (632 aa)
SLC26A3Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (762 aa)
CLCN5Chloride channel protein. (816 aa)
CASRCalcium sensing receptor. (1078 aa)
SLC26A8Testis anion transporter 1. (969 aa)
SLC26A1Sulfate anion transporter 1; Mediates sulfate transport with high affinity. Mediates oxalate transport. Mediates bicarbonate transport. Does not accept succinate as cosubstrate; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (701 aa)
SLC17A6Solute carrier family 17 member 6. (582 aa)
SLC12A9SLC12A9 isoform 1. (914 aa)
CLIC2Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (247 aa)
TTYH1Protein tweety homolog; Probable chloride channel; Belongs to the tweety family. (460 aa)
SLC1A1Amino acid transporter. (524 aa)
SLC26A9Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (887 aa)
SLC18A1Solute carrier family 18 member A1. (525 aa)
SLC26A7Anion exchange transporter. (663 aa)
SLC12A8Solute carrier family 12 (Potassium/chloride transporters), member 8. (714 aa)
GABRG2Gamma-aminobutyric acid type A receptor gamma2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (515 aa)
SLC12A1Solute carrier family 12 member 1. (1099 aa)
ANO4Anoctamin. (955 aa)
ANO9Anoctamin. (760 aa)
GABRA2Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (511 aa)
CLDN4Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
SLC12A4Solute carrier family 12 member 4. (1085 aa)
LOC469373LOW QUALITY PROTEIN: calcium-activated chloride channel regulator 1-like. (317 aa)
CLCN1-2Chloride voltage-gated channel 1. (989 aa)
SLC26A10SLC26A10 isoform 6. (553 aa)
GABRDGABRD isoform 6; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (501 aa)
ANO6Anoctamin. (931 aa)
CK820_G0035770GLRA2 isoform 4; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (338 aa)
CLIC2-2Chloride intracellular channel 2. (247 aa)
CLCN2Chloride channel protein. (898 aa)
CLIC5Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (410 aa)
ENSPTRP00000068002annotation not available (297 aa)
BEST1Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (664 aa)
CLIC6Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (674 aa)
GLRBGlycine receptor, beta; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (497 aa)
SLC26A5Prestin; Motor protein that converts auditory stimuli to length changes in outer hair cells and mediates sound amplification in the mammalian hearing organ; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (744 aa)
GABRR3Gamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene); Belongs to the ligand-gated ion channel (TC 1.A.9) family. (467 aa)
GABRA1Gamma-aminobutyric acid type A receptor alpha1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (471 aa)
CLDN4-2Claudin 4. (209 aa)
CLCN4Chloride channel protein. (760 aa)
PPP1R7Protein phosphatase 1, regulatory (Inhibitor) subunit 7. (376 aa)
ENSPTRP00000076491annotation not available (91 aa)
GABRR2Ubiquitin conjugating enzyme E2 J1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (465 aa)
ANO1Anoctamin. (986 aa)
SLC26A2Sulfate transporter; Sulfate transporter. May play a role in endochondral bone formation; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (739 aa)
ANO3Anoctamin. (1042 aa)
SLC17A8SLC17A8 isoform 1. (589 aa)
SLC12A6Solute carrier family 12 (Potassium/chloride transporters), member 6. (1151 aa)
SLC12A5Solute carrier family 12 member 5. (1139 aa)
FXYD3FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (143 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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