STRINGSTRING
SOX9 SOX9 BMP4 BMP4 NFATC4 NFATC4 NFATC3 NFATC3 BMP4-2 BMP4-2 PPARG PPARG LILRB4 LILRB4 ENSPTRP00000068326 ENSPTRP00000068326 ZNF512 ZNF512 NFIB NFIB RELA RELA RARA RARA PPARD PPARD REST REST SRF SRF PPARA PPARA PDGFB PDGFB ZNF512B ZNF512B TGFB1 TGFB1 GATA6 GATA6 YY1 YY1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SOX9Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
NFATC4Nuclear factor of activated T cells 4. (933 aa)
NFATC3Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3. (1075 aa)
BMP4-2Bone morphogenetic protein 4. (408 aa)
PPARGPeroxisome proliferator-activated receptor gamma isoform X2. (505 aa)
LILRB4LILRB4 isoform 7. (449 aa)
ENSPTRP00000068326annotation not available (488 aa)
ZNF512Zinc finger protein 512. (564 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
RELAV-rel reticuloendotheliosis viral oncogene homolog A (Avian). (551 aa)
RARARARA isoform 4. (624 aa)
PPARDPeroxisome proliferator-activated receptor delta. (441 aa)
RESTRE1 silencing transcription factor. (1097 aa)
SRFSerum response factor (C-fos serum response element-binding transcription factor). (508 aa)
PPARAPeroxisome proliferator-activated receptor alpha. (467 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
ZNF512BZinc finger protein 512B. (892 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
GATA6GATA binding protein 6. (594 aa)
YY1YY1 transcription factor. (414 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (38%) [HD]