21 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	REST	RE1 silencing transcription factor. (1097 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	YY1	YY1 transcription factor. (414 aa)
	SOX9	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa)
	GATA6	GATA binding protein 6. (594 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	ZNF512B	Zinc finger protein 512B. (892 aa)
	PDGFB	Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
	PPARA	Peroxisome proliferator-activated receptor alpha. (467 aa)
	SRF	Serum response factor (C-fos serum response element-binding transcription factor). (508 aa)
	RELA	V-rel reticuloendotheliosis viral oncogene homolog A (Avian). (551 aa)
	PPARD	Peroxisome proliferator-activated receptor delta. (441 aa)
	RARA	RARA isoform 4. (624 aa)
	NFIB	Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
	ZNF512	Zinc finger protein 512. (564 aa)
	ENSPTRP00000068326	annotation not available (488 aa)
	LILRB4	LILRB4 isoform 7. (449 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma isoform X2. (505 aa)
	BMP4-2	Bone morphogenetic protein 4. (408 aa)
	NFATC3	Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3. (1075 aa)
	NFATC4	Nuclear factor of activated T cells 4. (933 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	GATA6	ENSPTRP00000010780	ENSPTRP00000016858	Bone morphogenetic protein 4.	GATA binding protein 6.	0.546
BMP4	SOX9	ENSPTRP00000010780	ENSPTRP00000016293	Bone morphogenetic protein 4.	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	0.509
BMP4-2	GATA6	ENSPTRP00000080656	ENSPTRP00000016858	Bone morphogenetic protein 4.	GATA binding protein 6.	0.546
BMP4-2	SOX9	ENSPTRP00000080656	ENSPTRP00000016293	Bone morphogenetic protein 4.	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	0.509
GATA6	BMP4	ENSPTRP00000016858	ENSPTRP00000010780	GATA binding protein 6.	Bone morphogenetic protein 4.	0.546
GATA6	BMP4-2	ENSPTRP00000016858	ENSPTRP00000080656	GATA binding protein 6.	Bone morphogenetic protein 4.	0.546
GATA6	SOX9	ENSPTRP00000016858	ENSPTRP00000016293	GATA binding protein 6.	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	0.662
GATA6	SRF	ENSPTRP00000016858	ENSPTRP00000031085	GATA binding protein 6.	Serum response factor (C-fos serum response element-binding transcription factor).	0.580
GATA6	YY1	ENSPTRP00000016858	ENSPTRP00000011451	GATA binding protein 6.	YY1 transcription factor.	0.415
NFATC3	NFATC4	ENSPTRP00000087510	ENSPTRP00000089263	Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3.	Nuclear factor of activated T cells 4.	0.908
NFATC3	SRF	ENSPTRP00000087510	ENSPTRP00000031085	Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3.	Serum response factor (C-fos serum response element-binding transcription factor).	0.919
NFATC4	NFATC3	ENSPTRP00000089263	ENSPTRP00000087510	Nuclear factor of activated T cells 4.	Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3.	0.908
NFATC4	SRF	ENSPTRP00000089263	ENSPTRP00000031085	Nuclear factor of activated T cells 4.	Serum response factor (C-fos serum response element-binding transcription factor).	0.910
NFATC4	YY1	ENSPTRP00000089263	ENSPTRP00000011451	Nuclear factor of activated T cells 4.	YY1 transcription factor.	0.464
PDGFB	TGFB1	ENSPTRP00000024791	ENSPTRP00000018930	Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.582
PPARA	PPARD	ENSPTRP00000025003	ENSPTRP00000044222	Peroxisome proliferator-activated receptor alpha.	Peroxisome proliferator-activated receptor delta.	0.686
PPARA	PPARG	ENSPTRP00000025003	ENSPTRP00000076701	Peroxisome proliferator-activated receptor alpha.	Peroxisome proliferator-activated receptor gamma isoform X2.	0.505
PPARA	RELA	ENSPTRP00000025003	ENSPTRP00000054405	Peroxisome proliferator-activated receptor alpha.	V-rel reticuloendotheliosis viral oncogene homolog A (Avian).	0.498
PPARA	TGFB1	ENSPTRP00000025003	ENSPTRP00000018930	Peroxisome proliferator-activated receptor alpha.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.596
PPARD	PPARA	ENSPTRP00000044222	ENSPTRP00000025003	Peroxisome proliferator-activated receptor delta.	Peroxisome proliferator-activated receptor alpha.	0.686