Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSPTRP00000070902 | FBXO7 | ENSPTRP00000070902 | ENSPTRP00000024607 | annotation not available | F-box protein 7. | 0.571 |
| ENSPTRP00000070902 | LRRK2 | ENSPTRP00000070902 | ENSPTRP00000008254 | annotation not available | Leucine-rich repeat kinase 2. | 0.686 |
| ENSPTRP00000070902 | NFE2L2 | ENSPTRP00000070902 | ENSPTRP00000064585 | annotation not available | Nuclear factor (Erythroid-derived 2)-like 2. | 0.468 |
| ENSPTRP00000070902 | PINK1 | ENSPTRP00000070902 | ENSPTRP00000000500 | annotation not available | PTEN induced putative kinase 1. | 0.748 |
| FBXO7 | ENSPTRP00000070902 | ENSPTRP00000024607 | ENSPTRP00000070902 | F-box protein 7. | annotation not available | 0.571 |
| FBXO7 | LRRK2 | ENSPTRP00000024607 | ENSPTRP00000008254 | F-box protein 7. | Leucine-rich repeat kinase 2. | 0.657 |
| FBXO7 | PARK7 | ENSPTRP00000024607 | ENSPTRP00000078598 | F-box protein 7. | PARK7 isoform 1. | 0.670 |
| FBXO7 | PINK1 | ENSPTRP00000024607 | ENSPTRP00000000500 | F-box protein 7. | PTEN induced putative kinase 1. | 0.909 |
| GPR37 | GPR37L1 | ENSPTRP00000033642 | ENSPTRP00000003086 | G protein-coupled receptor 37. | G protein-coupled receptor 37 like 1. | 0.519 |
| GPR37L1 | GPR37 | ENSPTRP00000003086 | ENSPTRP00000033642 | G protein-coupled receptor 37 like 1. | G protein-coupled receptor 37. | 0.519 |
| HGF | IL10 | ENSPTRP00000072810 | ENSPTRP00000003208 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | 0.634 |
| HGF | MET | ENSPTRP00000072810 | ENSPTRP00000083162 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | 0.999 |
| IL10 | HGF | ENSPTRP00000003208 | ENSPTRP00000072810 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | 0.634 |
| LRRK2 | ENSPTRP00000070902 | ENSPTRP00000008254 | ENSPTRP00000070902 | Leucine-rich repeat kinase 2. | annotation not available | 0.686 |
| LRRK2 | FBXO7 | ENSPTRP00000008254 | ENSPTRP00000024607 | Leucine-rich repeat kinase 2. | F-box protein 7. | 0.657 |
| LRRK2 | PARK7 | ENSPTRP00000008254 | ENSPTRP00000078598 | Leucine-rich repeat kinase 2. | PARK7 isoform 1. | 0.879 |
| LRRK2 | PINK1 | ENSPTRP00000008254 | ENSPTRP00000000500 | Leucine-rich repeat kinase 2. | PTEN induced putative kinase 1. | 0.826 |
| LRRK2 | TRAP1 | ENSPTRP00000008254 | ENSPTRP00000013166 | Leucine-rich repeat kinase 2. | TNF receptor-associated protein 1. | 0.435 |
| MET | HGF | ENSPTRP00000083162 | ENSPTRP00000072810 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | 0.999 |
| MET | TRAP1 | ENSPTRP00000083162 | ENSPTRP00000013166 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | TNF receptor-associated protein 1. | 0.453 |
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